- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT00192998
The Serotonergic Transmitter System in Dementia and Affective Disorders
September 26, 2007 updated by: Rigshospitalet, Denmark
The aim of this project is to examine the serotonergic transmitter system using functional imaging of the brain (positron emission tomography [PET]) to gain knowledge about early pathophysiological changes in Alzheimer's dementia and mood disorders.
Study Overview
Status
Unknown
Conditions
Study Type
Observational
Enrollment (Anticipated)
100
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
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Copenhagen, Denmark, 2100
- Recruiting
- Neurobiological Research Unit
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Contact:
- Vibe G. Frokjaer, MD
- Phone Number: +45 3545 6714
- Email: vibe@nru.dk
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Principal Investigator:
- Vibe G. Frokjaer, MD
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Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
18 years and older (Adult, Older Adult)
Accepts Healthy Volunteers
Yes
Genders Eligible for Study
All
Description
Inclusion Criteria:
- Moderate to severe Alzheimer's disease
- Individuals genetically predisposed to affective disorder
- Healthy gender and age matched controls
Exclusion Criteria:
- Contraindications to magnetic resonance imaging (MRI)
- Use of psychoactive drugs
- Past or present affective disorder
- Other systemic diseases that may affect brain function
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Sponsor
Investigators
- Principal Investigator: Vibe G. Frokjaer, MD, Neurobiological Research Unit, Copenhagen University Hospital, Denmark
Publications and helpful links
The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start
October 1, 2003
Study Registration Dates
First Submitted
September 13, 2005
First Submitted That Met QC Criteria
September 13, 2005
First Posted (Estimate)
September 19, 2005
Study Record Updates
Last Update Posted (Estimate)
September 27, 2007
Last Update Submitted That Met QC Criteria
September 26, 2007
Last Verified
September 1, 2005
More Information
Terms related to this study
Additional Relevant MeSH Terms
Other Study ID Numbers
- SERT-AD
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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