Effects of Cognitive Intervention for Older Adults With Memory Decline: A Pilot Study

June 1, 2010 updated by: McGill University Health Centre/Research Institute of the McGill University Health Centre
The purpose of this study is to evaluate the effects of training in memory skills vs. use of external memory aids on everyday memory functioning in older people with mild cognitive impairment.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Detailed Description

Some older people experience memory loss that is worse than other people of their age, although they are not demented. This condition is known as mild cognitive impairment (MCI). Healthy older people can learn mnemonic strategies to improve their memory abilities. Can cognitive rehabilitation help people with MCI do better on mental tasks or maintain better functioning in everyday life? This study will evaluate the effects of two different rehabilitation programmes. Patients in the memory training group will learn mental strategies aimed at improving memory. Patients in the memory compensation group will learn to use external memory aids.

Study Type

Interventional

Enrollment (Anticipated)

30

Phase

  • Phase 1

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Canada
    • Quebec
      • Montreal, Quebec, Canada, H3A 1A1
        • McGill University Health Centre

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

65 years to 90 years (Older Adult)

Accepts Healthy Volunteers

No

Genders Eligible for Study

All

Description

Inclusion Criteria:

  • Clinical diagnosis of mild cognitive impairment

Exclusion Criteria:

  • Unable to speak and understand English
  • Unable to comply with treatment program due to significant comorbid illness; OR
  • Anticipated inability to attend all study sessions

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: Double

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: EA
Training in external memory aids
Behavioral: External memory aids training
8 weekly group sessions of training in the use of external memory aids, administered by clinical psychologist
Experimental: MT
Mnemonic training intervention
Behavioral: MEMO programme (Inst Universitaire de Geriatrie, Montreal)
8 weekly group training sessions in mnemonic strategies, administered by clinical psychologist.
No Intervention: WL
Wait-list control

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Time Frame
Rey Auditory Verbal Learning Test
Time Frame: 19-20 weeks
19-20 weeks
Wechsler Memory Scale - Logical Memory
Time Frame: 19-20 weeks
19-20 weeks
Face-name associations test
Time Frame: 19-20 weeks
19-20 weeks
Multifactorial Memory Questionnaire - Ability subscale
Time Frame: 19-20 weeks
19-20 weeks

Secondary Outcome Measures

Outcome Measure
Time Frame
Rivermead Behavioural Memory Test
Time Frame: 19-20 weeks
19-20 weeks
FAS test (non-memory)
Time Frame: 19-20 weeks
19-20 weeks
Category fluency (non-memory test)
Time Frame: 19-20 weeks
19-20 weeks
Victoria Stroop Test (non-memory test)
Time Frame: 19-20 weeks
19-20 weeks
Digit Span (non-memory test)
Time Frame: 19-20 weeks
19-20 weeks
Multifactorial Memory Questionnaire - Strategies and Contentment subscales
Time Frame: 19-20 weeks
19-20 weeks

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

McGill University Health Centre/Research Institute of the McGill University Health Centre

Investigators

  • Principal Investigator: Lisa Koski, PhD, Research Institute of the McGill University Health Centre

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start

May 1, 2008

Primary Completion (Actual)

May 1, 2010

Study Completion (Actual)

May 1, 2010

Study Registration Dates

First Submitted

January 24, 2008

First Submitted That Met QC Criteria

February 6, 2008

First Posted (Estimate)

February 7, 2008

Study Record Updates

Last Update Posted (Estimate)

June 2, 2010

Last Update Submitted That Met QC Criteria

June 1, 2010

Last Verified

June 1, 2010

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • PSY-07-015

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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