Constraint-Induced (CI) Movement Therapy for Progressive Multiple Sclerosis (MS)

June 10, 2008 updated by: National Multiple Sclerosis Society

Constraint-Induced Movement Therapy Trial for Progressive Multiple Sclerosis

This trial will evaluate whether progressive multiple sclerosis associated with hemiparesis may benefit from Constraint-Induced Movement Therapy.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Detailed Description

Constraint-Induced Movement Therapy was developed to treat stroke hemiparesis. Due to the similarity between multiple sclerosis and stroke in terms of chronic motor deficit, this trial will attempt to determine whether multiple sclerosis may benefit similarly from Constraint-Induced Movement Therapy.

Study Type

Interventional

Enrollment (Actual)

7

Phase

  • Phase 1

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • United States
    • Alabama
      • Birmingham, Alabama, United States, 35249
        • University of Alabama at Birmingham

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

21 years to 80 years (Adult, Older Adult)

Accepts Healthy Volunteers

No

Genders Eligible for Study

All

Description

Inclusion Criteria:

  • Chronic upper extremity motor deficit due to multiple sclerosis

Exclusion Criteria:

  • Relapse within 3 months of planned enrollment.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: N/A
  • Interventional Model: Single Group Assignment
  • Masking: None (Open Label)

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: 1
Treatment with Constraint-Induced Movement Therapy
Behavioral: Constraint-Induced Movement Therapy
Intensive practice with the hemiparetic arm for 30 contact hours
Other Names:
  • CI Therapy

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Time Frame
Improvement on the Motor Activity Log
Time Frame: One year
One year

Secondary Outcome Measures

Outcome Measure
Time Frame
Improvement on the Wolf Motor Function Test
Time Frame: Pre to post-treatment
Pre to post-treatment

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

National Multiple Sclerosis Society

Investigators

  • Principal Investigator: Victor W Mark, MD, University of Alabama at Birmingham

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start

March 1, 2007

Primary Completion (Actual)

April 1, 2008

Study Completion (Actual)

April 1, 2008

Study Registration Dates

First Submitted

June 9, 2008

First Submitted That Met QC Criteria

June 10, 2008

First Posted (Estimate)

June 11, 2008

Study Record Updates

Last Update Posted (Estimate)

June 11, 2008

Last Update Submitted That Met QC Criteria

June 10, 2008

Last Verified

June 1, 2008

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • CIMSTrial
  • PP1395

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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