Is Carotid Intima-media Thickness Affected by A1C Variability?

September 14, 2009 updated by: Yonsei University
This study was conducted to evaluate the effect of A1C variability on the progression of carotid artery intima-media thickness in type 2 diabetic patients.

Study Overview

Status

Completed

Conditions

Study Type

Observational

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

34 years to 79 years (Adult, Older Adult)

Accepts Healthy Volunteers

No

Genders Eligible for Study

All

Sampling Method

Probability Sample

Study Population

typeII, Fluroscopy in carotid once a year during 2 years.

Description

Inclusion Criteria:

  • type II
  • fluoroscopy in carotid once a year during 2 years

Exclusion Criteria:

  • type 1 diabetes
  • history or clinical evidence of coronary artery disease or cerebral or peripheral vascular disease
  • the presence of albuminuria (defined as 24 hour urine albumin excretion ≥ 30 mg)
  • renal dysfunction (defined as creatinine blood level ≥ 2.0 mg/dL)
  • hepatic dysfunction (defined as alanine aminotransferase and/or aspartate aminotransferase blood level ≥ 3 × upper normal limit)
  • smoking within the past 3 months prior to commencement of the study
  • use of any medication likely to alter IMT such as calcium channel blocker, thiazolidinedione, antiplatelet agent (clopidogrel, cilostazol)
  • use of glucocorticoid
  • pregnancy
  • severe concomitant disease such as cancer
  • infection
  • Cushing's syndrome
  • acromegaly, or any other disorder likely to alter glycemia
  • primary hypercholesterolemia
  • hypothyroidism or hyperthyroidism
  • use of any hormonal drugs
  • alcoholism or drug abuse

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Yonsei University

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

First Submitted

February 11, 2009

First Submitted That Met QC Criteria

February 11, 2009

First Posted (Estimate)

February 12, 2009

Study Record Updates

Last Update Posted (Estimate)

September 15, 2009

Last Update Submitted That Met QC Criteria

September 14, 2009

Last Verified

September 1, 2009

More Information

Terms related to this study

Other Study ID Numbers

  • 3-2006-0005

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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