Prognosis and Survival Estimates in Palliative Therapy

August 22, 2016 updated by: Heinrich-Heine University, Duesseldorf

Prognosis in Palliative Therapy - a Prospective Study on Survival Prognostication in Advanced Stage Cancer Patients

The accuracy of clinical survival estimates is tested in comparison to objective prognostic scores.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Detailed Description

  • At presentation a clinical survival estimate is obtained in each patient.
  • Survival is also estimated using published prognostic scores in palliative care.
  • Prognostic scores based on blood samples, general symptoms, complaints, and performance status are calculated and validated, respectively
  • Each patient completes questionnaires on psychological distress
  • Survival estimates are limited to 6 months.
  • Each patient is followed for at least 6 months.

Study Type

Observational

Enrollment (Actual)

612

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Germany
    • NRW
      • Duesseldorf, NRW, Germany, 40225
        • University Hospital Duesseldorf, Radiation Oncology Dept.
      • Duesseldorf, NRW, Germany, 40593
        • Sana Kliniken Duesseldorf Benrath
      • Duesseldorf, NRW, Germany, 40625
        • Sana Kliniken Duesseldorf Gerresheim, MVZ Onkologie

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

18 years and older (Adult, Older Adult)

Accepts Healthy Volunteers

No

Genders Eligible for Study

All

Sampling Method

Non-Probability Sample

Study Population

Consecutive unselected cancer patients referred for palliative treatment to one of the participating institutions.

Description

Inclusion Criteria:

  • oncologic disease confirmed
  • incurable locally advanced or metastatic disease
  • palliative treatment intended
  • age > 18
  • able to understand the study protocol
  • able to complete the forms with assistance if necessary

Exclusion Criteria:

  • therapy with curative intent
  • regular clinical follow-up visit without disease progression
  • ongoing therapy

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Observational Models: Cohort
  • Time Perspectives: Prospective

Cohorts and Interventions

Group / Cohort
Intervention / Treatment
Palliative Therapy
Patients referred to the oncology / radiation oncology departments for palliative therapy.
Other: no specific interventions
There are no specific interventions in this observational study

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Time Frame
Survival
Time Frame: 6 months
6 months

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Heinrich-Heine University, Duesseldorf

Investigators

  • Principal Investigator: Stephan Gripp, Dr., Universtity Hospital Duesseldorf, Radiation Oncology Department

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start

April 1, 2008

Primary Completion (Actual)

December 1, 2011

Study Completion (Actual)

August 1, 2016

Study Registration Dates

First Submitted

March 27, 2009

First Submitted That Met QC Criteria

March 27, 2009

First Posted (Estimate)

March 30, 2009

Study Record Updates

Last Update Posted (Estimate)

August 23, 2016

Last Update Submitted That Met QC Criteria

August 22, 2016

Last Verified

August 1, 2016

More Information

Terms related to this study

Keywords

Other Study ID Numbers

  • Pro-08

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

Subscribe