Maintenance of Vitamin D Level by UVB Radiation

April 8, 2010 updated by: Bispebjerg Hospital

How Much UVB Radiation is Necessary to Maintain Summer Vitamin D Level During Winter?

The purpose of the study is to determine the frequency of UVB radiations necessary to maintain the Vitamin D level during winter time.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Detailed Description

The work is addressing vitamin D production after UVB exposure and explore how much UVB radiation which is necessary to maintain a sufficient vitamin D level during the winter period in Denmark. 4 different UVB exposure times and 2 different UVB doses to 2 different body surface areas.

Study Type

Interventional

Enrollment (Actual)

75

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Denmark
    • NV
      • Copenhagen, NV, Denmark, 2400
        • Bispebjerg Hospital

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

18 years to 65 years (Adult, Older Adult)

Accepts Healthy Volunteers

Yes

Genders Eligible for Study

All

Description

Inclusion Criteria:

  • 18-65 years
  • Healthy

Exclusion Criteria:

  • Sun bed use
  • Holiday or business travel south of 45 degrees latitude during trial
  • Illness
  • Drug addiction
  • Pregnancy
  • Lactating

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Basic Science
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: Double

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Active Comparator: Group 1
Body surface area: 88 %
Radiation: Broadband UVB
UVB dose: 1 SED every week
Radiation: Broadband UVB
UVB dose: 4 SED every second week
Radiation: Broadband UVB
UVB dose: 1 SED every second week
Radiation: Broadband UVB
UVB dose: 1 SED every month
Active Comparator: Group 2
Body surface area: 22 %
Radiation: Broadband UVB
UVB dose: 1 SED every week
Radiation: Broadband UVB
UVB dose: 4 SED every second week
Radiation: Broadband UVB
UVB dose: 1 SED every second week
Radiation: Broadband UVB
UVB dose: 1 SED every month
Active Comparator: Group 3
Body surface area: 88 %
Radiation: Broadband UVB
UVB dose: 1 SED every week
Radiation: Broadband UVB
UVB dose: 4 SED every second week
Radiation: Broadband UVB
UVB dose: 1 SED every second week
Radiation: Broadband UVB
UVB dose: 1 SED every month
Active Comparator: Group 4
Body surface area: 88 %
Radiation: Broadband UVB
UVB dose: 1 SED every week
Radiation: Broadband UVB
UVB dose: 4 SED every second week
Radiation: Broadband UVB
UVB dose: 1 SED every second week
Radiation: Broadband UVB
UVB dose: 1 SED every month
No Intervention: Group 5
Body surface area: 0 %
Other: Control group
No intervention

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Vitamin D (nmol/l)
Time Frame: Monthly during 4 months
Vitamin D measured in a blood sample to define the relationship between frequency of UVB radiations and the Vitamin D level.
Monthly during 4 months

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Parathyroideahormone (pmol/l)
Time Frame: 4 months
To investigate whether parathyroideahormone is influenced by the UVB radiations.
4 months

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Bispebjerg Hospital

Collaborators

The Danish Medical Research Council

Investigators

  • Study Chair: Hans Christian Wulf, Professor, Bispebjerg Hospital, Department of Dermatology

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start

October 1, 2008

Primary Completion (Actual)

March 1, 2009

Study Completion (Actual)

April 1, 2010

Study Registration Dates

First Submitted

April 8, 2010

First Submitted That Met QC Criteria

April 8, 2010

First Posted (Estimate)

April 9, 2010

Study Record Updates

Last Update Posted (Estimate)

April 9, 2010

Last Update Submitted That Met QC Criteria

April 8, 2010

Last Verified

April 1, 2010

More Information

Terms related to this study

Keywords

Other Study ID Numbers

  • H-C-2008-072

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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