- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT01128283
Indicators of Inflammation and Coagulation in Sepsis
September 11, 2014 updated by: Gary Kinasewitz, University of Oklahoma
Temporal Behavior of Coagulation Factors, Cytokines and Tissue Injury Markers in Sepsis
We will collect blood samples from patients with the diagnosis of sepsis and other ICU patients.
We will describe the course of different mediator levels and organ injury markers and follow their progression throughout the course of the study.
Study Overview
Status
Completed
Conditions
Detailed Description
After informed consent is obtained 5 cc of blood is collected on the day of admission and on days 0, 1, 3, and 7 thereafter.
Plasma is collected and frozen for the subsequent measurement of biomarkers.
Study Type
Observational
Enrollment (Actual)
500
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
-
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Oklahoma
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Oklahoma City, Oklahoma, United States, 73104
- OU Medical Center
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Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
18 years and older (Adult, Older Adult)
Accepts Healthy Volunteers
No
Genders Eligible for Study
All
Sampling Method
Non-Probability Sample
Study Population
ICU patients
Description
Inclusion Criteria:
- Admission to the ICU
Exclusion Criteria:
- No blood draws scheduled
- Hemoglobin level < 6,5 gm/dl
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
Cohorts and Interventions
Group / Cohort |
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Sepsis
Patients with severe sepsis
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Non-infected
ICU patients without evidence of infection
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
Death
Time Frame: 30 days
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Survival at 30 days
|
30 days
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Sponsor
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start
January 1, 2002
Primary Completion (Actual)
May 1, 2014
Study Completion (Actual)
May 1, 2014
Study Registration Dates
First Submitted
May 20, 2010
First Submitted That Met QC Criteria
May 20, 2010
First Posted (Estimate)
May 21, 2010
Study Record Updates
Last Update Posted (Estimate)
September 12, 2014
Last Update Submitted That Met QC Criteria
September 11, 2014
Last Verified
September 1, 2014
More Information
Terms related to this study
Keywords
Additional Relevant MeSH Terms
Other Study ID Numbers
- 09681
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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