Cardiovascular Function in Sub Maximal Exercise and Performance in Three Daily Activity Tests After Stroke

Cardiovascular Function in Sub Maximal Exercise and Performance in Three Daily Activity Tests in Persons With Post Stroke Conditions

The purpose of this study is to explore the relationship between cardiovascular function of persons with post stroke conditions and their performance in three field tests. This is a validation study, aiming to determine during which of two activities VO2 measurements better express the functional restrictions caused by stroke, And to find out whether the Total Heart Beat Index can be used in the case of stroke survivors for the prediction of mechanical efficiency when measured during stair-climbing and of energy cost during treadmill walking.

The hypothesis is that Stair Climbing (STC) is a more suitable form of exercise capacity testing compared to Treadmill Walk (TMW) since it potentially requires a greater amount of external work, and therefore will show stronger correlation with functional tests demonstrating the same ability, whereas TMW does not utilize the movement capability of participants to the fullest.

Another hypothesis is that cardiac response to the exertion can be used as a predictor of those measures during these exertions in the post stroke population.

Study Overview

• Status: Unknown
• Conditions: Stroke; Hemiplegia

• Study Type: Observational
• Enrollment (Anticipated): 30

Contacts and Locations

Study Locations

• Israel
  • Ramat Gan, Israel
    • Recruiting
    • Israel Sport Center for the Disabled
    • Contact: Yeshayahu Hutzler, Dr.

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 40 years to 69 years (Adult, Older Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

• Sampling Method: Non-Probability Sample

Study Population

Participants are recruited in community centers designated for Disabled populations. They are leading a physically active life style, usually facilitated by an assistant.

Description

Inclusion Criteria:

• Having acquired stroke at least 1 year before testing
• Chronic weakness and/or spasticity of the affected side
• Independent stair-climbers (with hand-rail)
• Received medical clearance from a physician
• With cognitive level sufficient to comprehend instructions
• Participants' age will range between 40-69
• Use of walking aid is permitted as long as the participant is able to walk on a treadmill with hand-rail.

Exclusion Criteria:

• Unable to understand instructions
• Unable to ambulate
• Severe aphasia
• Heart failure or other medical conditions that preclude participation in the study.

Study Plan

How is the study designed?

Number of groups / cohorts

1

Cohorts and Interventions

Group / Cohort

People with Post Stroke Conditions; (a) having acquired stroke at least 1 year before testing. (b) Chronic weakness and/or spasticity of the affected side. (c) Independent stair-climbers (with hand-rail). (d) With cognitive level sufficient to comprehend instructions. (e) age range between 40-69. (f) Use of walking aid is permitted as long as the participant is able to walk on a treadmill with hand-rail. (g) No heart failure or other medical conditions that preclude participation in the study.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Time Frame
Exercise VO2	60 days
Exercise HR	60 days
Mechanical efficiency	60 days
Time for-Up-and-go (TUG) Test	60 days
Time for 10 m walk test	60 days
Distance for 6 min walk test	60 days

Collaborators and Investigators

• Sponsor: Hillel Yaffe Medical Center
• Collaborators: Israel Sport Center for the Disabled; Zinman College of Physical Education and Sports Sciences
• Investigators: Study Chair: Yeshayahu Hutzler, Dr., The Wingate Institute for Physical Education and Sports; Principal Investigator: Avraham Katz, MD, Israel Sport Center for the Disabled; Study Director: Galia Modai, The Wingate Institute for Physical Education and Sports

Publications and helpful links

General Publications

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Study record dates

Study Major Dates

• Study Start: June 1, 2011

Study Registration Dates

• First Submitted: June 28, 2011
• First Submitted That Met QC Criteria: July 17, 2011
• First Posted (Estimate): July 19, 2011

Study Record Updates

• Last Update Posted (Estimate): July 19, 2011
• Last Update Submitted That Met QC Criteria: July 17, 2011
• Last Verified: July 1, 2011

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Cardiovascular Diseases; Vascular Diseases; Cerebrovascular Disorders; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Neurologic Manifestations; Paralysis; Stroke; Hemiplegia
• Other Study ID Numbers: 54-2011