Inspiratory Resistive Loading and Proprioceptive Postural Control

Inspiratory Resistive Loading and Proprioceptive Postural Control in Healthy Individuals and Individuals With Recurrent Low Back Pain

Proprioceptive weighting changes may explain differences in postural control performance. In addition, the respiratory movement has a disturbing effect on postural balance. Postural balance seems to be impaired in individuals with respiratory disorders. Besides the essential role of respiration, the diaphragm may also play an important role in the control of the trunk and postural balance. Deficits in proprioception are found in a subgroup of patients with low back pain. In addition, disorders of respiration have been identified as strongly related to low back pain.

The aim of the study is to clarify whether loading of the inspiratory muscles has a negative effect upon proprioceptive postural control in healthy individuals and individuals with recurrent low back pain.

Study Overview

• Status: Completed
• Conditions: Low Back Pain; Respiratory Loading; Proprioceptive Impairment

• Study Type: Observational
• Enrollment (Actual): 40

Contacts and Locations

Study Locations

• Belgium
  • Vlaams-Brabant
    • Leuven, Vlaams-Brabant, Belgium, 3000
      • Katholieke Universiteit Leuven

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years to 45 years (Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

• Sampling Method: Probability Sample

Study Population

young flemish volunteers

Description

Inclusion Criteria individuals with low back pain:

• Age: 18-45 years old
• At least 1 year of low back pain with/without referred pain in buttock/thigh
• At least 3 episodes of disabling low back pain
• At least a score of 20% on the Oswestry Disability Index
• Willingness to sign the informed consent

Inclusion Criteria healthy individuals:

• Age: 18-45 years old
• No history of low back pain
• A score of 0% on the Oswestry Disability Index
• Willingness to sign the informed consent

Exclusion Criteria:

• History of major trauma and/or major orthopedic surgery of the spine, the pelvis or the lower quadrant
• One of the following conditions: Parkinson, multiple sclerosis, stroke, history of vestibular disorder, respiratory disease, pregnancy
• Radicular symptoms
• Not Dutch-speaking
• Strong opioids
• Neck pain
• Smoking history

Study Plan

How is the study designed?

Design Details

• Observational Models: Case-Control
• Time Perspectives: Cross-Sectional

Number of groups / cohorts

2

Cohorts and Interventions

Group / Cohort
Healthy individuals
Individuals with low back pain

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Proprioceptive postural control	Center of pressure displacement (force plate) in standing in response to local muscle vibration on ankle and back muscles to specifically detect the role of proprioception in postural control.	1 year

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Back muscle oxygenation	Near infrared spectroscopy: tissue oxygenation index (TOI) and haemoglobin	1 year
Kinematics	piezoresistive accelerometers	1 year
Respiratory muscle force	maximal inspiratory pressure - maximal expiratory pressure	1 year

Collaborators and Investigators

• Sponsor: KU Leuven
• Collaborators: Universitaire Ziekenhuizen KU Leuven
• Investigators: Principal Investigator: Simon Brumagne, PhD, KU Leuven

Publications and helpful links

General Publications

• Janssens L, Brumagne S, Polspoel K, Troosters T, McConnell A. The effect of inspiratory muscles fatigue on postural control in people with and without recurrent low back pain. Spine (Phila Pa 1976). 2010 May 1;35(10):1088-94. doi: 10.1097/BRS.0b013e3181bee5c3.

Study record dates

Study Major Dates

• Study Start: January 1, 2011
• Primary Completion (Actual): December 1, 2013
• Study Completion (Actual): December 1, 2013

Study Registration Dates

• First Submitted: January 4, 2012
• First Submitted That Met QC Criteria: February 23, 2012
• First Posted (Estimate): February 29, 2012

Study Record Updates

• Last Update Posted (Estimate): December 5, 2013
• Last Update Submitted That Met QC Criteria: December 4, 2013
• Last Verified: January 1, 2012

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Pain; Neurologic Manifestations; Back Pain; Low Back Pain
• Other Study ID Numbers: 2011_SBrumagne_HealthyLBP; 1.5.104.03, G.0674.09 (Other Grant/Funding Number: Research Foundation Flanders (FWO))