Effect of Water Rinsing After Topical Fluoride Application on Dental Plaque pH

March 30, 2012 updated by: Fatemeh Mazhari, Mashhad University of Medical Sciences

Effect of Water Rinsing After APF Application on Dental Plaque Acidogenicity

The aim of this study was to determine whether rinsing with water or cleansing teeth after topical fluoride therapy affect the dental plaque pH.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Study Type

Interventional

Enrollment (Actual)

25

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Iran, Islamic Republic of
    • Khorasan Razavi
      • Mashhad, Khorasan Razavi, Iran, Islamic Republic of
        • Dental School - Mashhad University of Medical Siences

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

21 years to 29 years (Adult)

Accepts Healthy Volunteers

Yes

Genders Eligible for Study

All

Description

Inclusion Criteria:

  • healthy people (Without any systemic disease)
  • normal unstimulated salivary rate

Exclusion Criteria:

  • Active dental caries
  • taking any medication with any effect on saliva rate
  • taking antibiotic (or antibacterial mouth rinses) during last 4 weeks
  • usig fluoride mouth rinses during last 2 weeks.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Prevention
  • Allocation: Randomized
  • Interventional Model: Crossover Assignment
  • Masking: Single

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: washing after 30 min
washing with water after 30 min following APF treatment
Procedure: cleansing teeth after topical fluoride therapy
washing with water 0, 15 or 30 min after APF treatment or cleansing teeth with cotton roll immediately following APF treatment.
Experimental: washing after 15 min
washing with water after 15 min following APF treatment
Procedure: cleansing teeth after topical fluoride therapy
washing with water 0, 15 or 30 min after APF treatment or cleansing teeth with cotton roll immediately following APF treatment.
Experimental: immediately washing with water
immediately washing with water after APF treatment
Procedure: cleansing teeth after topical fluoride therapy
washing with water 0, 15 or 30 min after APF treatment or cleansing teeth with cotton roll immediately following APF treatment.
Experimental: cleansing teeth with cotton roll
cleansing teeth with cotton roll immediately following APF treatment
Procedure: cleansing teeth after topical fluoride therapy
washing with water 0, 15 or 30 min after APF treatment or cleansing teeth with cotton roll immediately following APF treatment.
No Intervention: no fluoride therapy
control group

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Time Frame
dental plaque PH
Time Frame: the pH of 48-hour dental plaque was measured using plaque sampling method before (baseline pH) and after sucrose challenge at 5, 10,15,20,30 minutes
the pH of 48-hour dental plaque was measured using plaque sampling method before (baseline pH) and after sucrose challenge at 5, 10,15,20,30 minutes

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
maximum pH drop
Time Frame: 5,10,15,20 and 30 min after sucrose chalenge
5,10,15,20 and 30 min after sucrose chalenge
pH recovery time
Time Frame: within 30 min after sucrose challenge
time for returning to the baseline pH
within 30 min after sucrose challenge

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Mashhad University of Medical Sciences

Investigators

  • Principal Investigator: fatemeh mazhari, Associate Professor, Mashhad University of Medical Siences

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start

February 1, 2011

Primary Completion (Actual)

October 1, 2011

Study Completion (Actual)

November 1, 2011

Study Registration Dates

First Submitted

March 29, 2012

First Submitted That Met QC Criteria

March 30, 2012

First Posted (Estimate)

April 3, 2012

Study Record Updates

Last Update Posted (Estimate)

April 3, 2012

Last Update Submitted That Met QC Criteria

March 30, 2012

Last Verified

March 1, 2012

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • 89629

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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