CNAP Accuracy Dependent on Hemodynamic Variables

Accuracy of Continuous Non-invasive Arterial Pressure (CNAP) With Invasive Measurements Dependent on Cardiac Function, Vascular Resistance and Volume Status

Agreement of CNAP pressure with invasive pressure is evaluated dependent on hemodynamic variables achieved by a PICCO monitor.

Hypothesis: Low cardiac output and volume status but not high vascular resistance affect the accuracy of CNAP.

Study Overview

• Status: Completed
• Conditions: Accuracy and Precision of Noninvasive Measurement

Detailed Description

Agreement of CNAP pressure with invasive pressure is evaluated dependent on hemodynamic variables achieved by a PICCO monitor.

Hypothesis: Low cardiac output and volume status but not high vascular resistance affect the accuracy of CNAP. Body mass index and age may have impact on the accuracy of PPV measured non-invasively on the basis of volume-clamp technique.

• Study Type: Observational
• Enrollment (Actual): 50

Contacts and Locations

Study Locations

• Germany
  • Kiel, Germany, 24106
    • University Hospital, Schleswig-Holstein. Departement of Anaesthesia and Intensive Care Medicine

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years to 99 years (Adult, Older Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

• Sampling Method: Probability Sample

Study Population

Patients undergoing major surgery under general anaesthesia

Description

Inclusion Criteria:

• need for invasive blood pressure measurement

Exclusion Criteria:

• age under 18
• emergencies
• cardiac dysrhythmia

Study Plan

How is the study designed?

Number of groups / cohorts

1

Cohorts and Interventions

Group / Cohort
Major Surgery; Patients undergoing major surgery

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
arterial pressure	Accuracy and precision of CNAP in comparison with the gold standard	intraoperative

Collaborators and Investigators

• Sponsor: University Hospital Schleswig-Holstein
• Investigators: Principal Investigator: Jochen Renner, PD Dr., University Hospital, Schleswig-Holstein. Departement of Anaesthesia and Intensive Care Medicine; Principal Investigator: Robert Hanss, Prof. Dr., University Hospital, Schleswig-Holstein. Departement of Anaesthesia and Intensive Care Medicine

Study record dates

Study Major Dates

• Study Start: January 1, 2014
• Primary Completion (Actual): July 1, 2015
• Study Completion (Actual): July 1, 2015

Study Registration Dates

• First Submitted: December 4, 2012
• First Submitted That Met QC Criteria: December 4, 2012
• First Posted (Estimate): December 6, 2012

Study Record Updates

• Last Update Posted (Estimate): December 8, 2015
• Last Update Submitted That Met QC Criteria: December 5, 2015
• Last Verified: December 1, 2015

More Information

Terms related to this study

• Other Study ID Numbers: CNAP 2010_3