Volume Responsiveness Before SBT Predicts the Outcome of Mechanical Ventilation Weaning in Critically Ill Patients (weaning)

June 3, 2013 updated by: Jianfeng Xie, Southeast University, China

Volume Responsiveness Before Spontaneous Breath Trial Predicts the Outcome of Mechanical Ventilation Weaning in Critically Ill Patients

To evaluate the performance of volume responsiveness in predicting the outcome of mechanical ventilation weaning in critically ill patients.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Detailed Description

82 patients, 61 succeed and 21 failed

Study Type

Observational

Enrollment (Actual)

82

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • China
    • Jiangsu
      • Nanjing, Jiangsu, China, 210009
        • Zhongda Hospital

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

18 years and older (Adult, Older Adult)

Accepts Healthy Volunteers

Yes

Genders Eligible for Study

All

Sampling Method

Probability Sample

Study Population

The patients were mechanically ventilated and ready to undergo a spontaneous breathing trial (SBT) with a T-piece

Description

Inclusion Criteria:

  • mechanical ventilation

Exclusion Criteria:

  • pregnancy or breast-feeding
  • tracheostomy at baseline
  • myasthenia gravis or acute polyradiculoneuropathy
  • end-stage chronic illness

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

Cohorts and Interventions

Group / Cohort
Intervention / Treatment
successful weaning
the SUCCESS of SBT or not need for reintubation or noninvasive ventilation within 48 h following extubation
Device: PLR
passive leg raising test was done before and at the end of SBT
Other Names:
  • passive leg raising
failed weaning
the failure of SBT or the need for reintubation or noninvasive ventilation within 48 h following extubation
Device: PLR
passive leg raising test was done before and at the end of SBT
Other Names:
  • passive leg raising

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Time Frame
changes of cardiac index
Time Frame: 30 minutes
30 minutes

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Southeast University, China

Collaborators

Zhongda Hospital

Investigators

  • Principal Investigator: Zhimin DOU, Southeast university

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start

October 1, 2012

Primary Completion (Actual)

March 1, 2013

Study Completion (Actual)

March 1, 2013

Study Registration Dates

First Submitted

May 6, 2013

First Submitted That Met QC Criteria

May 29, 2013

First Posted (Estimate)

June 4, 2013

Study Record Updates

Last Update Posted (Estimate)

June 5, 2013

Last Update Submitted That Met QC Criteria

June 3, 2013

Last Verified

June 1, 2013

More Information

Terms related to this study

Additional Relevant MeSH Terms

Other Study ID Numbers

  • 10286

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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