Brain Imaging, Heart Rate Variability and Serum Fatty Acid in Subjects With Irritable Bowel Syndrome

July 1, 2014 updated by: Shin Kong Wu Ho-Su Memorial Hospital
This study is to analyze the relationship between brain structure, the heart rate variability and the serum fatty acid component of the irritable bowel syndrome patients.

Study Overview

Status

Completed

Conditions

Detailed Description

Several studies showed that the gray matter and white matter of the brain related to the symptoms of irritable bowel syndrome patients.

The investigators study is to analyse the relationship between thickness of cortex of irritable patients, the sympathetic tone and the serum fatty acid component of the irritable bowel syndrome patients. It is to clarify the mechanism of irritable bowel syndrome, whether the symptoms of irritable bowel syndrome are related to the thickness of cortex or inflammation status of the body.

Study Type

Observational

Enrollment (Actual)

69

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Taiwan
      • Taipei, Taiwan, 111
        • Shin Kong Wu Ho-Su Memorial Hospital

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

20 years to 50 years (Adult)

Accepts Healthy Volunteers

No

Genders Eligible for Study

Female

Sampling Method

Non-Probability Sample

Study Population

Irritable bowel syndrome patients, Control

Description

Inclusion Criteria:

  • female
  • between 20 and 50 years old
  • meet Rome III criteria

Exclusion Criteria:

  • colon and small intestinal disease
  • psychiatric disease patients
  • patients received major surgery in the past 5 years
  • diabetic patients
  • patients with metal implant

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Observational Models: Case-Control

Cohorts and Interventions

Group / Cohort
Irritable bowel syndrome, Control

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Time Frame
The relationship between brain structure, heart rate variability and fatty acid of the irritable bowel syndrome patients.
Time Frame: Patients who suffered from IBS for more than 5 years.
Patients who suffered from IBS for more than 5 years.

Secondary Outcome Measures

Outcome Measure
Time Frame
The relationship between thickness of brain cortex and the symptoms of irritable bowel syndrome
Time Frame: Patients who suffered from IBS for more than 5 years.
Patients who suffered from IBS for more than 5 years.

Other Outcome Measures

Outcome Measure
Time Frame
The relationship between heart rate variability and symptoms of irritable bowel syndrome patients.
Time Frame: Patients who suffered from IBS for more than 5 years.
Patients who suffered from IBS for more than 5 years.
The relationship between component of fatty acid and symptoms of irritable bowel syndrome patients.
Time Frame: Patients who suffered from IBS for more than 5 years.
Patients who suffered from IBS for more than 5 years.

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Shin Kong Wu Ho-Su Memorial Hospital

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start

January 1, 2013

Primary Completion (Actual)

September 1, 2013

Study Completion (Actual)

September 1, 2013

Study Registration Dates

First Submitted

June 4, 2014

First Submitted That Met QC Criteria

July 1, 2014

First Posted (Estimate)

July 2, 2014

Study Record Updates

Last Update Posted (Estimate)

July 2, 2014

Last Update Submitted That Met QC Criteria

July 1, 2014

Last Verified

June 1, 2014

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • SKH-8302-102-DR-14

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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