- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT02577653
Posturographic Characteristics of Eccentric, Isometric and Concentric Movements
February 16, 2017 updated by: Frederick Carrick, PhD, FACCN, Carrick Institute for Graduate Studies
Determine the posturographic characteristics of eccentric, isometric and concentric movements in healthy subjects as well as in subjects with chronic, orthopedic conditions / pain not involving the lower extremities.
The squatting movement (going down from a stand up position, bending the ankle, knee and hip joints, and then returning to the stand up position, while not lifting the feet from the supporting ground surface) is a simple motion that involves all three types of movements: eccentric (the going down), isometric (holding the down position for a couple of seconds) and concentric (the coming up).
It is hypothesized that non-healthy subjects will not have "smooth" movements, and posturography could be used to separate between healthy and non-healthy subjects.
Study Overview
Status
Withdrawn
Conditions
Intervention / Treatment
Detailed Description
Subjects will undergo Computerized Dynamic Posturography (CDP) testing using the modified Clinical Testing of Sensory Integration in Balance (mCTSIB) protocol: the subjects will be required to stand on a hard or compliant surface (a 4" tall foam cushion of known mechanical properties) in a comfortable posture, feet shoulder width, with eyes open or closed, head straight and arms to the side and free to move, gazing forward, and breathing normally.
Subsequently, subjects will be asked to stand first on the right leg and then on the left leg, raising the other leg (flexing the hip about 45 degrees), bending (flexing) the knee 90 degrees, keeping the arms extended and moving them laterally (abduct shoulders to 45 degrees and extend both elbows) to help maintaining balance with eyes open.
Finally, subjects will be asked to perform 10 repetition of the squatting movement, with the operator pacing them (telling them when to start and when to stop the movements).
The results of the mCTSIB, combined with an initial physical and neurological examination will be used to classify the subjects into the healthy and non healthy group.
Study Type
Interventional
Phase
- Not Applicable
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
-
-
Georgia
-
Savannah, Georgia, United States, 31405
- Optim Orthopedics - DeRenne
-
-
Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
18 years and older (Adult, Older Adult)
Accepts Healthy Volunteers
Yes
Genders Eligible for Study
All
Description
Inclusion Criteria:
- subjects with chronic, orthopedic conditions / pain
Exclusion Criteria:
- involving the lower extremities
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
- Primary Purpose: Basic Science
- Allocation: N/A
- Interventional Model: Single Group Assignment
- Masking: None (Open Label)
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
---|---|
Other: subjects
participant undergoing posturographic evaluation
|
Subjects will undergo CDP testing using the modified Clinical Testing of Sensory Integration in Balance (mCTSIB) protocol.
Subsequently, subjects will be asked to stand first on the right leg and then on the left leg with eyes open.
Finally, subjects will be asked to perform 10 repetition of the squatting movement, with the operator pacing them (telling them when to start and when to stop the movements).
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
Stability Score
Time Frame: immediately after data collection
|
The Stability Score (calculated as percentage ratio of the actual sway and the theoretical limit of stability) will be used to investigate if there is any difference between healthy controls and subjects affected by chronic pain not involving the lower extremities.
Statistical tools such t-tests and correlation coefficients will be used for assess if there is a difference between the two groups
|
immediately after data collection
|
Secondary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
average velocity moment [mm^2/s]
Time Frame: immediately after data collection
|
The average velocity moment (calculated as as the product of sway velocity path length) will be used to investigate if there is any difference between healthy controls and subjects affected by chronic pain not involving the lower extremities.
Statistical tools such t-tests and correlation coefficients will be used for assess if there is a difference between the two groups
|
immediately after data collection
|
sway path length [mm]
Time Frame: immediately after data collection
|
The sway path length (the distance traveled during the test) will be used to investigate if there is any difference between healthy controls and subjects affected by chronic pain not involving the lower extremities.
Statistical tools such t-tests and correlation coefficients will be used for assess if there is a difference between the two groups
|
immediately after data collection
|
frequency content [Hz]
Time Frame: immediately after data collection
|
The frequency content (calculated using FFT) will be used to investigate if there is any difference between healthy controls and subjects affected by chronic pain not involving the lower extremities.
Statistical tools such t-tests and correlation coefficients will be used for assess if there is a difference between the two groups
|
immediately after data collection
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start
October 1, 2015
Primary Completion (Actual)
January 1, 2017
Study Completion (Actual)
January 1, 2017
Study Registration Dates
First Submitted
October 2, 2015
First Submitted That Met QC Criteria
October 14, 2015
First Posted (Estimate)
October 16, 2015
Study Record Updates
Last Update Posted (Actual)
February 20, 2017
Last Update Submitted That Met QC Criteria
February 16, 2017
Last Verified
February 1, 2017
More Information
Terms related to this study
Keywords
Additional Relevant MeSH Terms
Other Study ID Numbers
- CI-IRB-20150818005
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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