SPECTA: Screening Cancer Patients for Efficient Clinical Trial Access (SPECTA)

November 2, 2023 updated by: European Organisation for Research and Treatment of Cancer - EORTC

SPECTA is a quality assured platform for collecting clinicopathologically annotated biological material, imaging data, operative images, environmental assessment, questionnaires as well as patient-reported outcomes from cancer patients to support biospecimen-based translational research and clinical cancer research, including biomarker discovery to improve the understanding of tumor biology and cancer patients care.

Study Overview

Status

Recruiting

Conditions

All Tumor Types

Intervention / Treatment

Detailed Description

Patients are recruited in the platform for the research purpose of 4 downstream projects. For more information, please have a look at the "Groups and cohorts" section.

Study Type

Observational

Enrollment (Estimated)

4975

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

Name: EORTC HQ
Phone Number: +32 2 774 1611
Email: specta@eortc.org

Study Locations

Austria
- - Vienna, Austria, 1090
    - Recruiting
    - Medical University Vienna - General Hospital AKH
    - Principal Investigator:
      
      Matthias Preusser, MD
Belgium
- - Aalst, Belgium, 9300
    - Recruiting
    - Onze Lieve Vrouw Ziekenhuis
    - Principal Investigator:
      
      Peter Schatteman
    - Principal Investigator:
      
      Adelheid Roelstraete
  - Antwerp, Belgium
    - Recruiting
    - ZNA Middelheim
    - Principal Investigator:
      
      Dirk Schrijvers, MD
  - Brussels, Belgium, 1200
    - Recruiting
    - Cliniques Universitaires Saint-Luc
    - Principal Investigator:
      
      Thierry Pieters
    - Principal Investigator:
      
      Benedicte Brichard
    - Principal Investigator:
      
      Marc Van den Eynde
    - Principal Investigator:
      
      Frank Cornelis
    - Principal Investigator:
      
      Francois Duhoux
    - Principal Investigator:
      
      Jean-Pascal Machiels
  - Brussels, Belgium, 1000
    - Recruiting
    - Hopitaux Universitaires - Institut Jules Bordet
    - Principal Investigator:
      
      Thierry Berghmans, MD
    - Principal Investigator:
      
      Christos Sotiriou, MD
    - Principal Investigator:
      
      Christiane Jungels
    - Principal Investigator:
      
      Francesco Sclafani
  - Brussels, Belgium, 1000
    - Recruiting
    - Universitair Ziekenhuis Brussel
    - Principal Investigator:
      
      Bart Neyns
  - Gent, Belgium, 9000
    - Recruiting
    - Universitair Ziekenhuis Gent
    - Principal Investigator:
      
      Nicolaas Lumen
    - Principal Investigator:
      
      Karen Geboes, MD
    - Principal Investigator:
      
      Sylvie Rottey
    - Principal Investigator:
      
      Lore Lapeire
  - Leuven, Belgium, 3000
    - Recruiting
    - U.Z. Leuven - Campus Gasthuisberg
    - Principal Investigator:
      
      Sabine Tejpar
    - Principal Investigator:
      
      christophe Dooms
    - Principal Investigator:
      
      Sandra Jacobs
  - Liège, Belgium, 4000
    - Recruiting
    - Centre Hospitalier Régional de la Citadelle
    - Principal Investigator:
      
      Frederique Bustin
  - Liège, Belgium, 4000
    - Recruiting
    - C.H.U. Sart-Tilman
    - Principal Investigator:
      
      Christine Gennigens
  - Namur, Belgium, 5000
    - Recruiting
    - CHU Site Sainte-Elisabeth-UCL Namur
    - Principal Investigator:
      
      Jean-Charles Goeminne
  - Turnhout, Belgium, 2300
    - Recruiting
    - AZ Turnhout - Campus Sint Elisabeth
    - Principal Investigator:
      
      Leen Mortier
  - Yvoir, Belgium, 5530
    - Recruiting
    - CHU Mont Godinne - UCL Namur
    - Principal Investigator:
      
      Sebahat Ocak
    - Principal Investigator:
      
      Lionel D'Hondt
Croatia
- - Zagreb, Croatia, 10000
    - Recruiting
    - University Hospital Centre Zagreb
    - Principal Investigator:
      
      Marija Gamulin
Cyprus
- - Stróvolos, Cyprus, 2006
    - Recruiting
    - Bank Of Cyprus Oncology Centre
    - Principal Investigator:
      
      Demetris Papamichael
Czechia
- - Prague, Czechia, 150 06
    - Recruiting
    - University Hospital Motol
    - Principal Investigator:
      
      Katerina Kopeckova, Dr
    - Principal Investigator:
      
      Jan Plzak, Dr
Estonia
- - Tallinn, Estonia, 13419
    - Recruiting
    - North Estonia Medical Centre - Mustamäe unit
    - Principal Investigator:
      
      Kersti Oselin
    - Principal Investigator:
      
      Anu Planken
    - Principal Investigator:
      
      Aidi Adamson-Raieste
France
- - Angers, France, 49055
    - Recruiting
    - Institut de Cancerologie de l'Ouest (ICO) - Centre Paul Papin
    - Principal Investigator:
      
      Jean-Sebastien Frenel
  - Avignon, France, 84902
    - Recruiting
    - Centre Hospitalier Avignon
    - Principal Investigator:
      
      Nicolas Cloarec
  - Besancon, France, 25030
    - Recruiting
    - Chru de Besancon - Hopital Jean Minjoz
    - Principal Investigator:
      
      Antoine Thiery-Vuillemin
  - Beuvry, France, Beuvry
    - Recruiting
    - Centre de Radiotherapie Pierre Curie
    - Principal Investigator:
      
      Jean-Briac Prevost
  - Bordeaux, France, 33075
    - Recruiting
    - CHU de Bordeaux - Groupe Hospitalier Saint-André - Hopital Saint-Andre
    - Principal Investigator:
      
      Laurence Digue
  - Bordeaux, France, FR 33076
    - Recruiting
    - Institut Bergonié
    - Principal Investigator:
      
      Antoine Italiano
  - Bron, France, 69677 Cedex
    - Recruiting
    - CHU Lyon - Hopital neurologique Pierre Wertheimer
    - Principal Investigator:
      
      Francois Ducray
  - Bron, France, 69500
    - Recruiting
    - CHU de Lyon - Hopital Louis Pradel
    - Principal Investigator:
      
      Thomas Pierret
  - Creteil, France, 94010
    - Recruiting
    - Centre Hopitalier Intercommunal De Creteil
    - Principal Investigator:
      
      Gaelle Rousseau Bussac
  - Dijon, France, 21079
    - Recruiting
    - Centre Georges-Francois-Leclerc
    - Principal Investigator:
      
      Alice Hervieu
  - Grenoble, France, 38043
    - Recruiting
    - CHU de Grenoble - La Tronche - Hôpital A. Michallon
    - Principal Investigator:
      
      Anne-Claire Toffart
  - La Roche Sur Yon, France, 85925 Cedex 9
    - Recruiting
    - Centre Hospitalier Départemental Vendée
    - Principal Investigator:
      
      Frank Priou
  - Lille, France
    - Recruiting
    - Centre Oscar Lambret
    - Principal Investigator:
      
      Nicolas Penel
    - Principal Investigator:
      
      Anne-Sophie Defachelles
  - Lille, France, 59037 Cedex
    - Recruiting
    - CHRU de Lille
    - Principal Investigator:
      
      Apolline Monfilliette-Djelad
  - Lyon, France, 69008
    - Recruiting
    - Centre Léon Bérard
    - Principal Investigator:
      
      Jean-Yves Blay
    - Principal Investigator:
      
      Beatrice Fervers
  - Lyon, France, 69003
    - Recruiting
    - CHU De Lyon - Hôpital Edouard Herriot
    - Principal Investigator:
      
      Thomas Walter
  - Lyon, France, 69495
    - Recruiting
    - CHU de Lyon - Hopital Lyon Sud
    - Principal Investigator:
      
      Julien Peron
  - Marseille, France, 13015
    - Recruiting
    - Assistance Publique - Hopitaux de Marseille - Hopital Nord
    - Principal Investigator:
      
      Laurent Greillier, MD
  - Metz-Tessy, France, 74370
    - Recruiting
    - Centre Hospitalier D'annecy
    - Principal Investigator:
      
      Laetitia Stefani
  - Montpellier, France, 34295 CEDEX 5
    - Recruiting
    - CHU Montpellier-Hopital Arnaud De Villeneuve
    - Principal Investigator:
      
      Benoit Roch
  - Montpellier Cedex 5, France, 34298
    - Recruiting
    - Institut du Cancer de Montpellier
    - Principal Investigator:
      
      Marie Vinches
  - Morlaix, France, 29600
    - Recruiting
    - Centre hospitalier des pays de Morlaix
    - Principal Investigator:
      
      Karim Amrane
  - Nancy, France, 54100
    - Recruiting
    - Centre d'Oncologie de Gentilly
    - Principal Investigator:
      
      Dominique Spaeth
  - Nice, France, 06200 CEDEX 3
    - Recruiting
    - CHU de Nice - Hôpital de l'Archet
    - Principal Investigator:
      
      Henri Montaudie
  - Paris, France, 75651
    - Recruiting
    - Assistance Publique - Hopitaux de Paris - La Pitie Salpetriere
    - Principal Investigator:
      
      Laurence Leenhardt
    - Principal Investigator:
      
      Marc Sanson
  - Paris, France, 75571
    - Recruiting
    - Assistance Publique - Hopitaux de Paris - Hopital Saint Antoine
    - Principal Investigator:
      
      Romain Cohen
  - Paris, France
    - Recruiting
    - Assitance Publique - Hopitaux de Paris - Hopital Saint-Louis
    - Principal Investigator:
      
      Martine Bagot, MD
    - Principal Investigator:
      
      Luis Teixeira, MD
  - Paris, France, 75674
    - Recruiting
    - Groupe Hospitalier Paris Saint-Joseph - Hopital Saint Joseph
    - Principal Investigator:
      
      Charles Naltet
  - Rennes, France
    - Recruiting
    - Centre Eugène Marquis
    - Principal Investigator:
      
      Marc Pracht
  - Saint Nazaire, France, 44600
    - Recruiting
    - Clinique Mutualiste de l'Estuaire - Centre d'oncologie
    - Principal Investigator:
      
      Thierry Chatellier
  - Saint-Herblain, France, 44805
    - Recruiting
    - Institut de Cancerologie de l'Ouest (ICO) - Centre Rene Gauducheau
    - Principal Investigator:
      
      Jean-Sebastien Frenel
  - Saint-Priest-en-Jarez, France, 42270
    - Recruiting
    - Institut de Cancérologie de la Loire Lucien Neuwirth
    - Principal Investigator:
      
      Nardjes Djehal
  - Strasbourg, France, 67200
    - Recruiting
    - Institut de Cancerologie Strasbourg Europe (formar Paul Strauss)
    - Principal Investigator:
      
      Thierry Petit
  - Toulouse, France, 31059
    - Recruiting
    - CHU Toulouse - Hopital Larrey
    - Principal Investigator:
      
      Julien Mazieres
  - Villejuif, France
    - Recruiting
    - Gustave Roussy
    - Principal Investigator:
      
      Benjamin Besse, MD
    - Principal Investigator:
      
      Patricia PAUTIER, MD
    - Principal Investigator:
      
      Caroline Even, DR
Germany
- - Berlin, Germany, 13353
    - Recruiting
    - Charite - Universitaetsmedizin Berlin - Campus Virchow-Klinikum
    - Principal Investigator:
      
      Beate Rau
  - Dresden, Germany, 01307
    - Recruiting
    - Universitaetsklinikum Carl Gustav Carus
    - Principal Investigator:
      
      Gunnar Folprecht
  - Jena, Germany, 07447
    - Recruiting
    - Universitaetsklinikum Jena
    - Principal Investigator:
      
      Orlando Guntinas-Lichius
  - Leer, Germany, 26789
    - Recruiting
    - Onkologie UnterEms, Leer-Papenburg-Emden
    - Principal Investigator:
      
      Lothar Mueller
Greece
- - Athens, Greece, 151 23
    - Recruiting
    - Hygeia Hospital
    - Principal Investigator:
      
      Evangelia Razis, MD
    - Principal Investigator:
      
      Rigakos Georgios
  - Athens, Greece, 11521
    - Recruiting
    - NIMTS - Veterans Administration Hospital
    - Principal Investigator:
      
      Athanasios Karampeazis
  - Athens, Greece, 12462
    - Recruiting
    - Athens University - Attikon University General Hospital
    - Principal Investigator:
      
      Evangelia Papadavid
  - Ioánnina, Greece, 45500
    - Suspended
    - Ioannina University Hospital
Italy
- - Alessandria, Italy, 15100
    - Recruiting
    - Ospedale Civile Santi Antonio e Biagio e Cesare Arrigo
    - Principal Investigator:
      
      Federica Grosso
  - Bologna, Italy, 40138
    - Recruiting
    - Alma Mater Studiorium Universita di Bologna - Loc. Ospedala Sant'Orsolo
    - Principal Investigator:
      
      Maria Pantaleo, Dr
  - Brescia, Italy, 25123
    - Recruiting
    - Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia
    - Principal Investigator:
      
      Paolo Bossi
  - Cremona, Italy, 26100
    - Recruiting
    - Azienda Istituti Ospitalieri di Cremona
    - Principal Investigator:
      
      Daniele Generali
  - Genova, Italy, 16132
    - Recruiting
    - IRCCS Azienda Ospedaliera Universitaria San Martino "IST" Istituto Nazionale per la Ricerca sul Cancro
    - Principal Investigator:
      
      Francesco Papadia
  - Legnago, Italy, 37045
    - Recruiting
    - Azienda Unita Locale Socio-Sanitaria N. 9-Mater Salutis Hospital
    - Principal Investigator:
      
      Jacopo Giuliani
  - Milano, Italy, 20133
    - Recruiting
    - IRCCS - Istituto Neurologico Carlo Besta
    - Principal Investigator:
      
      Marica Eoli
  - Napoli, Italy, 80147
    - Recruiting
    - Ospedale del Mare
    - Principal Investigator:
      
      Angelica Petrillo
    - Principal Investigator:
      
      Pasqualina Giordano
  - Orbassano, Italy, 10043
    - Recruiting
    - Universita Di Torino - Ospedale S. Luigi Gonzaga
    - Principal Investigator:
      
      Silvia Novello
  - Padova, Italy, 35128
    - Recruiting
    - IRCCS - Istituto Oncologico Veneto
    - Principal Investigator:
      
      Giuseppe Lombardi, Dr
  - Pavia, Italy, 27100
    - Recruiting
    - Istituti Clinici Scientifici Maugeri
    - Principal Investigator:
      
      Giovanni Battista Ivaldi, MD
  - Roma, Italy, 00144
    - Recruiting
    - Regina Elena National Cancer Center
    - Principal Investigator:
      
      Edoardo Pescarmona
  - Torino, Italy, 10126
    - Recruiting
    - Azienda Ospedaliera Citta della Salute e della Scienza di Torino - Ospedale Molinette
    - Principal Investigator:
      
      Paolo Gontero
  - Torino, Italy, 10126
    - Recruiting
    - Azienda Ospedaliera Città della Salute e della Scienza di Torino - Ospedale San Giovanni - Dipartimento Neuroscienze
    - Principal Investigator:
      
      Roberta Ruda, Dr
  - Torino, Italy, 10126
    - Recruiting
    - Azienda Ospedaliera Città della Salute e della Scienza di Torino - Ospedale Sant'Anna
    - Principal Investigator:
      
      Maria Grazia Bau
Lithuania
- - Vilnius, Lithuania, 08660
    - Recruiting
    - Lithuanian Oncology Center-Nat. Cancer Inst
    - Principal Investigator:
      
      Birute Brasiuniene
Netherlands
- - Amsterdam, Netherlands, 1105 AZ
    - Recruiting
    - Amsterdam UMC - Locatie AMC
    - Principal Investigator:
      
      Tromp Jacqueline
  - Amsterdam, Netherlands, 1066 CX
    - Recruiting
    - The Netherlands Cancer Institute-Antoni Van Leeuwenhoekziekenhuis
    - Principal Investigator:
      
      Winette van der Graaf
  - Groningen, Netherlands, 9713 GZ
    - Recruiting
    - University Medical Center Groningen
    - Principal Investigator:
      
      Jaco De Haan
  - Maastricht, Netherlands, 6202 AZ
    - Recruiting
    - Academisch Ziekenhuis Maastricht
    - Principal Investigator:
      
      Lizza Hendriks
  - Nijmegen, Netherlands, 6525GA
    - Recruiting
    - Radboud University Medical Center Nijmegen
    - Principal Investigator:
      
      Petronella Beatrix Ottevanger
Poland
- - Gdansk, Poland, 80 211
    - Recruiting
    - Medical University of Gdansk
    - Principal Investigator:
      
      Rafal Dziadziuszko
  - Gliwice, Poland, 44-101
    - Recruiting
    - Maria S. Curie Memorial Institute-Gliwice Branche
    - Principal Investigator:
      
      Barbara Jarzab
  - Poznan, Poland, 61 866
    - Recruiting
    - The Great Poland Cancer Centre
    - Principal Investigator:
      
      Piotr Kolenda
  - Warsaw, Poland
    - Recruiting
    - Maria Sklodowska-Curie Memorial Cancer Centre
    - Principal Investigator:
      
      Lucjan Wyrwicz, MD
    - Principal Investigator:
      
      Piotr Rutkowski
Portugal
- - Lisboa, Portugal, 1998-018
    - Recruiting
    - Hospital Cuf Descobertas
    - Principal Investigator:
      
      Sofia Azambuja Braga
  - Lisboa, Portugal, 1449-005
    - Recruiting
    - Centro Hospitalar de Lisboa Ocidental- San Francisco Xavier Hospital
    - Principal Investigator:
      
      Mariana Malheiro Rodrigues
  - Lisboa, Portugal, 1350-352
    - Recruiting
    - Hospital CUF Tejo
    - Principal Investigator:
      
      Mario Fontes-Sousa, Dr
  - Lisboa, Portugal, 1099-023 CODEX
    - Recruiting
    - Instituto Portugues de Oncologia de Lisboa Francisco Gentil - EPE
    - Principal Investigator:
      
      Isabel Sargento
    - Principal Investigator:
      
      Teresa Almodovar
  - Porto, Portugal, 4099-001
    - Recruiting
    - Centro Hospitalar do Porto- Hospital de Santo Antonio
    - Principal Investigator:
      
      Manuel Magalhaes
  - Porto, Portugal, 4200-162
    - Recruiting
    - Instituto Portugues de Oncologia do Porto
    - Principal Investigator:
      
      Julio Oliveira
  - Vila Nova De Gaia, Portugal, 4430
    - Recruiting
    - Cen.Hospitalar Vila Nova Gaia
    - Principal Investigator:
      
      Andreia Capela
Romania
- Cluj Napoca
  - Cluj, Cluj Napoca, Romania, 400058
    - Recruiting
    - Medisprof Cancer Center srl
    - Principal Investigator:
      
      Adrian Udrea, Dr
Serbia
- - Belgrade, Serbia, 11000
    - Recruiting
    - University Clinic Centre Serbia - Pulmonoloy clinic
    - Principal Investigator:
      
      Milica Kontic Jovanovic
  - Belgrade, Serbia, 11000
    - Recruiting
    - University Clinical Center of Serbia - Clinic for ENT and MFH
    - Principal Investigator:
      
      Ana Jotic
Slovenia
- - Golnik, Slovenia, 4204
    - Recruiting
    - University Clinic Golnik
    - Principal Investigator:
      
      Urska Janzic
  - Maribor, Slovenia, 2000
    - Recruiting
    - University medical center Maribor
    - Principal Investigator:
      
      Nina Fokter Dovnik
Spain
- - Barcelona, Spain, 08041
    - Recruiting
    - Hospital de la Santa Creu i Sant Pau
    - Principal Investigator:
      
      Ivana Gabriela Sullivan
  - Barcelona, Spain, 08035
    - Recruiting
    - Vall d'Hebron Institut d'Oncologia
    - Contact:
      
      Josep Tabernero
      
      Phone Number: +34934894350
    - Principal Investigator:
      
      Josep Tabernero
  - Barcelona, Spain, 08036
    - Recruiting
    - Hospital Clinic Universitari de Barcelona
    - Principal Investigator:
      
      Laura Mezquita
  - Elche, Spain, 03203
    - Recruiting
    - Hospital General Universitario de Elche
    - Principal Investigator:
      
      Javier Gallego Plazas
    - Principal Investigator:
      
      Maria Guirado Risueno
  - Girona, Spain, 17007
    - Recruiting
    - ICO Girona - Hospital Doctor Josep Trueta (Institut Catala D'Oncologia)
    - Principal Investigator:
      
      Adelaida Garcia Velasco
  - L'Hospitalet De Llobregat, Spain, 08907
    - Recruiting
    - ICO L'Hospitalet- Hospital Universitari de Bellvitge
    - Principal Investigator:
      
      Samantha Aso
  - Madrid, Spain, 28031
    - Recruiting
    - Hospital Universitario Infanta Leonor
    - Principal Investigator:
      
      Jacobo Rogado
  - Madrid, Spain, 28034
    - Recruiting
    - Hospital Universitario Ramon Y Cajal
    - Principal Investigator:
      
      Maria Angeles Vaz Salgado
    - Principal Investigator:
      
      Alfonso Cortes Salgado
    - Principal Investigator:
      
      Pilar Garrido Lopez
  - Madrid, Spain, 28041
    - Recruiting
    - Hospital Universitario 12 de Octubre
    - Principal Investigator:
      
      Luis Paz-Ares
    - Principal Investigator:
      
      Rocio Garcia-Carbonero
  - Madrid, Spain, 28009
    - Recruiting
    - Hospital Infantil Universitario Niño Jesús
    - Principal Investigator:
      
      Alba Rubio San Simón
  - Madrid, Spain, 28040
    - Recruiting
    - Hospital Universitario San Carlos
    - Principal Investigator:
      
      Gloria Marquina, MD
    - Principal Investigator:
      
      Antonio Casado Herraez, MD
  - Madrid, Spain, 28223
    - Recruiting
    - Hospital Universitario Quirónsalud
    - Principal Investigator:
      
      Belen Rubio Viqueira
    - Principal Investigator:
      
      Jesus Miranda Poma
    - Principal Investigator:
      
      Elena Almagro Casado
    - Principal Investigator:
      
      Lucia Gonzalez Cortijo
  - Malaga, Spain, 29010
    - Recruiting
    - Hospital Universitario Virgen de la Victoria
    - Principal Investigator:
      
      Jose Carlos Benitez Montanez
  - Valencia, Spain, 46010
    - Recruiting
    - Hospital Clinico Universitario de Valencia
    - Principal Investigator:
      
      Andres Cervantes
  - Valladolid, Spain, 47011
    - Recruiting
    - Hospital Clinico Universitaro De Valladolid
    - Principal Investigator:
      
      Ricardo Sanchez-Escribano Morcuende, Dr
Switzerland
- - Aarau, Switzerland, 5000
    - Recruiting
    - Hirslanden Klinik-Tumor Zentrum Aarau
    - Principal Investigator:
      
      Razvan Popescu
  - Saint Gallen, Switzerland, 9007
    - Recruiting
    - Kantonsspital St Gallen
    - Principal Investigator:
      
      Christina Appenzeller
  - Zurich, Switzerland, 8091
    - Recruiting
    - UniversitaetsSpital Zurich - Neurology Clinic
    - Principal Investigator:
      
      Patrick Roth
  - Zurich, Switzerland, 8091
    - Recruiting
    - UniversitaetsSpital Zurich
    - Principal Investigator:
      
      Panagiotis Balermpas
United Kingdom
- - Birmingham, United Kingdom, B15 2TH
    - Recruiting
    - University Hospitals Birmingham NHS Foundation Trust (UHB) - UHB-Queen Elisabeth Medical Centre
    - Principal Investigator:
      
      Julia Scarisbrick, MD
    - Principal Investigator:
      
      Tahir Shah, MD
    - Principal Investigator:
      
      Helen Benghiat, MD
  - Birmingham, United Kingdom, B312AP
    - Recruiting
    - Royal Orthopaedics Hospital, NHS Trust
    - Principal Investigator:
      
      Lee Jeys
  - Cambridge, United Kingdom, CB2 0QQ
    - Recruiting
    - Cambridge University Hospital NHS - Addenbrookes Hospital
    - Principal Investigator:
      
      Helen Hatcher, MD
  - Cardiff, United Kingdom, CF14 2TL
    - Recruiting
    - Velindre NHS Trust - Velindre Cancer Centre
    - Principal Investigator:
      
      Mererid Evans, MD
    - Principal Investigator:
      
      Waters Simon
  - Coventry, United Kingdom, CV2 2DX
    - Recruiting
    - University Hospitals Coventry and Warwickshire NHS Trust - University Hospital
    - Principal Investigator:
      
      Martin Weickert, MD
  - Edinburgh, United Kingdom, EH4 2XU
    - Recruiting
    - NHS Lothian - Western General Hospital
    - Principal Investigator:
      
      Sharon Peoples
    - Principal Investigator:
      
      Mark Stares
  - Glasgow, United Kingdom, G12 OYN
    - Recruiting
    - NHS Greater Glasgow and Clyde - Beatson West of Scotland Cancer Centre - Gartnavel General Hospital
    - Principal Investigator:
      
      Jeffrey David White
  - Hereford, United Kingdom, HR1 2ER
    - Recruiting
    - Hereford County Hospital
    - Principal Investigator:
      
      Marios Decatris
  - Leeds, United Kingdom, LS9 7TF
    - Recruiting
    - Leeds Teaching Hospitals NHS Trust - St. James's University Hospital
    - Principal Investigator:
      
      Daniel Stark
  - London, United Kingdom, NW3 2QG
    - Recruiting
    - Royal Free Hospital
    - Principal Investigator:
      
      Martyn Caplin
  - Manchester, United Kingdom, M20 4BX
    - Recruiting
    - The Christie NHS Foundation Trust
    - Principal Investigator:
      
      Martin McCabe
    - Principal Investigator:
      
      Ciara O'Brien
    - Principal Investigator:
      
      Colin Lindsay
    - Principal Investigator:
      
      Jorge Barriuso
    - Principal Investigator:
      
      Angela Lamarca
- Denbighshire
  - Bodelwyddan, Denbighshire, United Kingdom, LL18 5UJ
    - Recruiting
    - Betsi Cadwaladr University Health Board - Glan Clwyd District General Hospital
    - Principal Investigator:
      
      Angel Garcia-Alonso

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

12 years and older (Child, Adult, Older Adult)

Accepts Healthy Volunteers

Sampling Method

Non-Probability Sample

Study Population

Patients with pathologically confirmed selected tumor types.

Description

Patients with pathologically confirmed selected tumor types (at site or centrally);
Mandatory availability of adequate human biological material (HBM);
Centrally performed confirmation of HBM adequacy in terms of quality and quantity for SPECTA downstream project requirements;
Age ≥ 12 years;
Absence of any psychological, familial, sociological or geographical condition potentially hampering compliance with the study protocol and follow-up schedule;
Written informed consent according to applicable legal and ethical requirements;

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

Observational Models: Cohort
Time Perspectives: Prospective

Number of groups / cohorts

Cohorts and Interventions

Group / Cohort	Intervention / Treatment
RP-1828 IMMUcan The goal is to generate broad molecular and cellular profiling data of the tumour and its microenvironment from cancer patients integrated with clinical data, to understand how the immune system and tumours interact, and the impact of current therapeutic interventions. Tumor types: Thorax, Head and Neck, Breast, Gastrointestinal, Genito Urinary	Genetic: RP-1828 IMMUcan WES, lcWGS and RNAseq, multiplex IF and IMC
RP-1759 AYA/TYA (CLOSED for recruitment since December 2021) The pilot study will be focusing on young adults (12 to 29 years old) with rare cancer to understand better the biology of the tumor in this specific population, and compare it to children and adults with similar disease, as well as to improve the inclusion of young adults into clinical trials. Tumor type: CNS	Genetic: RP-1759 AYA/TYA WES, RNAseq and EPIC array
RP-1843 Arcagen (CLOSED for recruitment since November 2022) This is a collaborative project between EORTC and EURACAN to perform molecular characterisation of rare cancers patients, using Foundation Medicine tests. The goal of this project is to get a better understanding of the genomic landscape of rare cancers and potentially help define possibilities for targeted treatments/clinical trials for this population. Tumor types: all 10 EURACAN domains	Genetic: RP-1843 Arcagen NGS panel
RP-1920 BioRadon The primary objective is to assess the correlation between the molecular profiles of NSCLC patients and indoor radon concentration, measured with an alpha-particle detector (a standardized and validated way of measuring indoor radon). Tumor type: Thorax	Genetic: RP-1920 BioRadon NGS panel

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
To establish a quality assured platform to improve the understanding of tumor biology and cancer patients care Time Frame: 5 years	material (including imaging data) as well as patient-reported outcomes from patients with cancer diagnosis to support biospecimen-based translational research and biomarker discovery to improve the understanding of tumor biology and cancer patients care.	5 years

Secondary Outcome Measures

Outcome Measure	Time Frame
To perform biospecimen and data based high quality research aiming to better understand the biology of cancer, and/or how it is currently managed and/or how to better diagnose and treat it in the future; Time Frame: 5 years	5 years
To investigate the molecular pathways related to the development of specific tumors from a biological point of view; Time Frame: 5 years	5 years
To investigate the effect of cancer treatment on the tumor, microenvironment and patients globally; Time Frame: 5 years	5 years
To collect large series of homogeneous clinical data to analyse the disease course and treatment performed; Time Frame: 5 years	5 years
To investigate the prevalence and validate the prognostic or predictive value of novel biomarkers in cancers; Time Frame: 5 years	5 years
To perform biospecimen and data based high quality research aiming to facilitate the discovery of new test for tumor biomarkers or facilitate the establishment of validated tests for tumor biomarkers; Time Frame: 5 years	5 years
To identify patients with molecular alterations in their tumor that can be matched to biomarker-driven clinical trials, to facilitate enrollment of cancer patients in biomarker-driven clinical trials. Time Frame: 5 years	5 years

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

European Organisation for Research and Treatment of Cancer - EORTC

Investigators

Study Chair: Benjamin Besse, Pr., European Organisation for Research and Treatment of Cancer - EORTC

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

May 3, 2017

Primary Completion (Estimated)

March 1, 2026

Study Completion (Estimated)

March 1, 2026

Study Registration Dates

First Submitted

July 13, 2016

First Submitted That Met QC Criteria

July 13, 2016

First Posted (Estimated)

July 15, 2016

Study Record Updates

Last Update Posted (Actual)

November 3, 2023

Last Update Submitted That Met QC Criteria

November 2, 2023

Last Verified

November 1, 2023

More Information

Terms related to this study

Keywords

Other Study ID Numbers

EORTC-1553

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

Clinical Trials on All Tumor Types

Hospices Civils de Lyon

Not yet recruiting

Characterisation of TLR4+ Blood Cells in Patients With Solid Cancer (ODYSSEE)

All Types of Solid Cancer

France
Philips Electronics Nederland B.V. acting through...

Completed

Skin Tone Measurement Method Investigation for Pulse Oximetry

Pulse Oximetry | Skin Types

Netherlands
Tel-Aviv Sourasky Medical Center

Unknown

The Role of 68Ga-FAPI-04 PET/CT as a Problem Solving Imaging Modality in Various Malignancies

Different Types of Cancer

Israel
Universität Duisburg-Essen
University Hospital, Essen; Helios Hospital Krefeld; Oslo Centre for Biostatistics...

Recruiting

Cardiorespiratory Fitness in Children and Adolescents After Cancer Treatment. (POWER)

All Types of Pediatric Cancer

Germany
Washington University School of Medicine

Completed

Immune Characterization of Subcutaneous Adipose Tissue (ATI)

Determine Immune Cell Types in Subcutaneous Adipose Tissue

United States
Tel Aviv University
Weizmann Institute of Science

Recruiting

Digital Delivery of Patient Education: A Case Study of Symptom Self-Management During Cancer Treatment

Digital Education Interventions | Knowledge Types (Mechanistic Versus Procedural)

Israel
Assistance Publique - Hôpitaux de Paris

Completed

Emergence of Fluoroquinolone Resistance in Commensal Flora (FQEMERG)

All Types of Infections

France
UPECLIN HC FM Botucatu Unesp
Fundação de Amparo à Pesquisa do Estado de São Paulo

Completed

Toxicogenomic and Immunocytotoxic Effects of Propofol and Isoflurane Anesthetics in Patients Undergoing Elective Surgery

DNA Damage | Patients in Good Health | Types of General Anesthesia

Brazil
Nova Scotia Health Authority

Completed

Intensive Short-Term Dynamic Psychotherapy (ISTDP) in the Emergency Department (ISTDPED)

Somatic Complaints of Multiple Types

Canada
Merck Sharp & Dohme LLC

Completed

A Study to Evaluate the Safety, Immune Response, and Efficacy of Gardasil (V501, qHPV) in Mid-Adult Women (V501-019)

Prevention | Papillomavirus Infection | Healthy Adult Female Participants | Human Papillomavirus Recombinant Vaccine Quadrivalent, Types 6, 11, 16, 18

Clinical Trials on RP-1828 IMMUcan

Ewha Womans University

Completed

Comparison of Nonposterior- and Posterior-Stabilized Mobile-Bearing Total Knee Arthroplasty

Osteoarthritis

Korea, Republic of
Repare Therapeutics
Debiopharm International SA

Recruiting

Study of RP-6306 Alone or in Combination With RP-3500 or Debio 0123 in Patients With Advanced Solid Tumors (MYTHIC)

Advanced Solid Tumor

United States, Canada, Denmark
DePuy International

Terminated

A Study to Compare the Press Fit Condylar (P.F.C.) Sigma Rotating-platform High-flexion (RP-F) Versus the Press Fit Condylar (P.F.C.) Sigma Rotating-platform (RP) Knee Implants

Knee Osteoarthritis

Spain, United Kingdom
New York State Psychiatric Institute
National Institute of Mental Health (NIMH)

Completed

Cognitive Behavioral Therapy Plus Motivational Interviewing for Treatment of Obsessive-Compulsive Disorder

Obsessive-Compulsive Disorder

United States
Swiss Group for Clinical Cancer Research

Terminated

Extended Pelvic Lymph Node Dissection vs. no Pelvic Lymph Node Dissection at Radical Prostatectomy for intermediate-and High-risk Prostate Cancer

Prostate Cancer

Switzerland
Rocket Pharmaceuticals Inc.

Active, not recruiting

Gene Therapy for Male Patients With Danon Disease (DD) Using RP-A501; AAV9.LAMP2B

Danon Disease

United States
Rocket Pharmaceuticals Inc.

Unknown

A Clinical Trial to Evaluate the Safety of RP-L102 in Pediatric Subjects With Fanconi Anemia Subtype A

Fanconi Anemia Complementation Group A

United States
Rocket Pharmaceuticals Inc.

Recruiting

A Phase 1, Dose Escalation Trial of RP-A601 in Subjects With PKP2 Variant-Mediated Arrhythmogenic Cardiomyopathy (PKP2-ACM)

PKP2 Arrhythmogenic Cardiomyopathy (PKP2-ACM)

United States
Rocket Pharmaceuticals Inc.

Active, not recruiting

Gene Therapy for Fanconi Anemia, Complementation Group A

Fanconi Anemia Complementation Group A

United States
Rocket Pharmaceuticals Inc.
California Institute for Regenerative Medicine (CIRM)

Completed

A Clinical Trial to Evaluate the Safety and Efficacy of RP-L201 in Subjects With Leukocyte Adhesion Deficiency-I

Leukocyte Adhesion Defect - Type I

Spain, United States, United Kingdom

SPECTA: Screening Cancer Patients for Efficient Clinical Trial Access (SPECTA)

Study Overview

Status

Conditions

Intervention / Treatment

Detailed Description

Study Type

Enrollment (Estimated)

Contacts and Locations

Study Contact

Study Locations

Participation Criteria

Eligibility Criteria

Ages Eligible for Study

Accepts Healthy Volunteers

Sampling Method

Study Population

Description

Study Plan

How is the study designed?

Design Details

Number of groups / cohorts

Cohorts and Interventions

Group / Cohort

Intervention / Treatment

What is the study measuring?

Primary Outcome Measures

Outcome Measure

Measure Description

Time Frame

Secondary Outcome Measures

Outcome Measure

Time Frame

Collaborators and Investigators

Sponsor

Investigators

Study record dates

Study Major Dates

Study Start (Actual)

Primary Completion (Estimated)

Study Completion (Estimated)

Study Registration Dates

First Submitted

First Submitted That Met QC Criteria

First Posted (Estimated)

Study Record Updates

Last Update Posted (Actual)

Last Update Submitted That Met QC Criteria

Last Verified

More Information

Terms related to this study

Keywords

Other Study ID Numbers

Clinical Trials on All Tumor Types

Clinical Trials on RP-1828 IMMUcan

Search Similar Trials

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Venezuela

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations