Body Schema Alterations in Musculoskeletal Disorders : Effect of Laterality (Schem-TMS)

Body Schema Alterations in Patients Suffering From Musculoskeletal Disorders. Does Disorder Laterality Influence Recruitment of Cerebral Areas Involved in Voluntary Motricity?

This study assess ocular movements in a hand laterality judgment task in a population of musculoskeletal disorders. Reaction time, error rate and visual strategy are compared between musculoskeletal disorders and healthy patients, and between the different locations of the disorder.

Study Overview

• Status: Completed
• Conditions: Carpal Tunnel Syndrome; Chronic Low Back Pain; Musculoskeletal Disorder; Rotator Cuff Tendinitis
• Intervention / Treatment: Other: hand laterality judgment task

Detailed Description

Musculoskeletal disorders are a major public health issue. Recent studies showed that body schema alterations are involved in the chronification of those disorders. Those alterations bring the opportunity for new exploration or therapeutic solutions. Our hypothesis is that musculoskeletal disorders lead to motor imagery alterations relative to body schema disorders. Reaction time extension et error rate increase in a hand laterality judgment task would confirm that hypothesis. It is assumed that body schema alterations of patients suffering from musculoskeletal disorders could change with localisation, dependant on disorder's laterality and distality.

It is a monocentric, prospective, case-control trial, with 4 subgroups of 30 patients : shoulder rotator cuff tendinopathy, carpal tunnel syndrome, chronic low back pain, healthy subjects. We compare reaction time and error rate on a hand laterality judgement task. In that task, participants are asked to identify hand right or left laterality, when those hand is presented on a computer screen, by answering with the keyboard. Hands are shown on palmar or dorsal view and with 12 different angles of rotation. An eye-tracking device register participant eye movements during the task.

• Study Type: Observational
• Enrollment (Actual): 71

Contacts and Locations

Study Locations

• France
  • Angers, France, 49100
    • CHU Angers

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years to 65 years (Adult, Older Adult)
• Accepts Healthy Volunteers: N/A

• Sampling Method: Non-Probability Sample

Study Population

patients refered to the Hospital University of Angers or the Hand Center in Trelazé for one of the musculoskeletal disorders meeting the inclusion criterias.

Description

Inclusion Criteria:

• normal visual acuity
• social security affiliation
• signing consent
• rotator cuff tendinopathy, chronic low back pain, carpal tunnel syndrome or healthy subject

Exclusion Criteria:

• recent trauma or surgery
• psychiatric or neurological disorder
• psychotropic consumption
• previous experience with motor imagery
• bad french comprehension
• protected persons
• other painful affection than the inclusion criteria

Study Plan

How is the study designed?

Design Details

• Observational Models: Case-Control
• Time Perspectives: Prospective

Number of groups / cohorts

4

Cohorts and Interventions

Group / Cohort	Intervention / Treatment
Shoulder rotator cuff tendinopathy; unilateral rotator cuff tendinopathy, 3 months or more duration, confirmed by imagery,	Other: hand laterality judgment task; participants are asked to identify laterality of the hand presented on the screen
chronic low back pain; non specific chronic (3 months) low back pain	Other: hand laterality judgment task; participants are asked to identify laterality of the hand presented on the screen
carpal tunnel syndrome; unilateral carpal tunnel syndrome, confirmed by electromyogram, 3 months or more duration	Other: hand laterality judgment task; participants are asked to identify laterality of the hand presented on the screen
control; healthy subjects	Other: hand laterality judgment task; participants are asked to identify laterality of the hand presented on the screen

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
error rate at the hand laterality judgment task	number of errors divided by the total number of hands presented	1 hour
reaction time	time to press on the keyboard the answer "Right" or "Left" after the hand was presented	1 hour

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
visual strategy	assessment of the image's areas most fixed with the eyes	1 hour

Collaborators and Investigators

• Sponsor: University Hospital, Angers

Study record dates

Study Major Dates

• Study Start (Actual): July 13, 2018
• Primary Completion (Actual): July 12, 2022
• Study Completion (Actual): July 12, 2022

Study Registration Dates

• First Submitted: June 6, 2018
• First Submitted That Met QC Criteria: June 21, 2018
• First Posted (Actual): June 25, 2018

Study Record Updates

• Last Update Posted (Actual): June 11, 2024
• Last Update Submitted That Met QC Criteria: June 10, 2024
• Last Verified: June 1, 2024

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Nervous System Diseases; Pain; Neurologic Manifestations; Wounds and Injuries; Muscular Diseases; Neuromuscular Diseases; Rupture; Shoulder Injuries; Tendon Injuries; Mononeuropathies; Peripheral Nervous System Diseases; Median Neuropathy; Nerve Compression Syndromes; Cumulative Trauma Disorders; Sprains and Strains; Back Pain; Low Back Pain; Rotator Cuff Injuries; Carpal Tunnel Syndrome; Tendinopathy; Musculoskeletal Diseases
• Other Study ID Numbers: 2018-A00354-51

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: UNDECIDED

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No