Symptom-limited Stair Climbing Test in Heart Failure

Effectiveness of Symptom-limited Stair-climbing Test in the Determination of the Exercise Capacity of Patients With Chronic Heart Failure

Aims: To assess the efficacy of symptom-limited stair-climbing test (SLSCT), in determining the exercise capacities of patients with chronic heart failure (CHF) in comparison with cardiopulmonary exercise test (CPET) and 6-minute walk test(6MWT) and to interpret the results according to the clinical status of the patients.

Methods: Thirty-one patients, aged 50-75 years, with stage II-III CHF according to the New York Heart Association Classification and left ventricular ejection fraction (LVEF) of ≤45% were included. The demographic and clinical characteristics of the patients were recorded. Exercise capacity was assessed by SLSCT, 6MWT, and CPET. The duration of patients' performance in the test, reasons for ending the test and predicted maximal oxygen consumption (VO2max) were recorded. Heart rate (HR), blood pressure (BP), dyspnoea severity [Modified Borg Scale (MBS)] and peripheral oxygen saturation were recorded. Pulmonary functions were assessed by spirometry.

Study Overview

• Status: Completed
• Conditions: Chronic Heart Failure
• Intervention / Treatment: Other: Exercise Test

• Study Type: Observational
• Enrollment (Actual): 31

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 50 years to 75 years (Adult, Older Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

• Sampling Method: Probability Sample

Study Population

Thirty-one patients age 65.52±7.57 years with stage II-III according to the NYHA classification, diagnosed with CHF, with a LVEF of 45% or less admitted to study.

Description

Inclusion Criteria:

• 50-75 years of age
• NYHA stage II-III
• LVEF of 45% or less
• Independently walking and climbing stairs
• Volunteer to participate in research

Exclusion Criteria:

• Any acute or chronic condition that would limit exercise capacity other than CHF
• Insufficient mental status to perform tests and surveys
• Orthopaedic problem limiting exercise test in lower extremity
• Severe obesity or there is a secondary cause for obesity
• Uncontrolled cardiac arrhythmia
• Unstable angina

Study Plan

How is the study designed?

Design Details

• Observational Models: Other
• Time Perspectives: Prospective

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Symptom-Limited Stair-Climbing Test(SLSCT)	predicted VO2 max (ml/kg/min)	baseline
Six-Minute Walk Test(6MWT)	predicted VO2 max (ml/kg/min)	baseline
Cardiopulmonary Exercise Test(CPET)	predicted VO2 max (ml/kg/min)	baseline

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Heart Rate	Heart Rate beats/min	immediately after the procedure
Left Ventricular Ejection Fraction	Ecocardiography	baseline
Blood Pressure	Systolic and diastolic blood pressure (mmHg)	immediately after the procedure

Other Outcome Measures

Outcome Measure	Measure Description	Time Frame
FVC l/sec	Forced Vital Capacity l/sec	baseline
FEF 25-75 l/sec	Forced Expiratory Flow 25-75 l/sec	baseline
PEF l/sec	Peak Expiratory Flow l/sec	baseline
FEV1 %	Forced Expiratory Volume in One Second %	baseline
FVC %	Forced Vital Capacity %	baseline
FEF 25-75 %	Forced Expiratory Flow %	baseline
PEF %	Peak Expiratory Flow %	baseline
FEV1 l/sec	Forced Vital Capacity l/sec	bseline
FEV1/FVC	FEV1/FVC %	bseline

Collaborators and Investigators

• Sponsor: KTO Karatay University

Study record dates

Study Major Dates

• Study Start (Actual): January 13, 2017
• Primary Completion (Actual): November 10, 2017
• Study Completion (Actual): November 12, 2017

Study Registration Dates

• First Submitted: April 6, 2020
• First Submitted That Met QC Criteria: April 15, 2020
• First Posted (Actual): April 20, 2020

Study Record Updates

• Last Update Posted (Actual): April 20, 2020
• Last Update Submitted That Met QC Criteria: April 15, 2020
• Last Verified: April 1, 2020

More Information

Terms related to this study

• Keywords: exercise capacity; chronic heart failure; symptom-limited stair-climbing test
• Additional Relevant MeSH Terms: Heart Diseases; Cardiovascular Diseases; Heart Failure
• Other Study ID Numbers: busra.alkan

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No