Effects of Ketogenic Diet in Body Builders

November 13, 2020 updated by: Antonio Paoli, University of Padova

Effects of Two Months of Ketogenic Diet on Body Composition, Muscle Strength and Blood Parameters in Competitive Natural Body Builders

the study sought to investigate the influence of 8 weeks of a very low carbohydrate ketogenic diet on body composition, muscle strength, muscle area and blood parameters in competitive natural body builders.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Detailed Description

nineteen natural body builders were randomly assigned to a ketogenic diet (KD) group or to a normal diet group (ND) with a traditional meal pattern. The two diets were isocaloric and included the same amount of protein per kg of body weight; but differed in the distribution of fats and carbohydrates; the latter were kept below 5% daily (less than 50g/day) in the KD group while represented 55% of the caloric intake in the WD group During the experimental period, training loads were similar in the two groups. Athletes were tested before and after 8 weeks of the intervention. Body composition , basal metabolism, muscle strength and blood parameters were measured.

Study Type

Interventional

Enrollment (Actual)

19

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Italy
      • Padova, Italy, 35131
        • Nutrition and Exercise Lab, DSB, University of Padova

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

20 years to 40 years (ADULT)

Accepts Healthy Volunteers

Yes

Genders Eligible for Study

Male

Description

Inclusion Criteria:

  • at least 5 years of training experiences
  • competing in recognized body building category

Exclusion Criteria:

  • adherence to special diets
  • use of nutritional supplements (except a daily multivitamin-mineral and/or protein supplement)
  • use of medications (steroids)
  • diabetes or metabolic diseases

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: BASIC_SCIENCE
  • Allocation: RANDOMIZED
  • Interventional Model: PARALLEL
  • Masking: SINGLE

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
EXPERIMENTAL: Ketogenic Diet
KD group consumed less than 50g/day of carbohydrates
Other: Ketogenic Diet
KD group consumed less than 50g/day of carbohydrates
ACTIVE_COMPARATOR: Normal Diet
ND group consumed 55% of the caloric intake from carbohydrates
Other: Normal Diet
ND group consumed 55% of the caloric intake from carbohydrates

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Fat Mass
Time Frame: 8 weeks
fat mass measured through body impedence analyser
8 weeks
Lean Body Mass
Time Frame: 8 weeks
lean body mass mass measured through body impedence analyser
8 weeks
Maximal muscle strength
Time Frame: 8 weeks
muscle strength measured via 1-RM test
8 weeks

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
blood glucose
Time Frame: 8 weeks
glucose as milligram per deciliter
8 weeks
testosterone
Time Frame: 8 weeks
Testosterone free as picogram per milliliter
8 weeks
inflammatory cytokines
Time Frame: 8 weeks
IL6, IL1β, TNFα measured as nanogram per deciliter
8 weeks
resting metabolism
Time Frame: 8 weeks
resting energy expenditure measured as Kcal / day
8 weeks

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

University of Padova

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (ACTUAL)

January 1, 2020

Primary Completion (ACTUAL)

August 31, 2020

Study Completion (ACTUAL)

October 31, 2020

Study Registration Dates

First Submitted

November 9, 2020

First Submitted That Met QC Criteria

November 9, 2020

First Posted (ACTUAL)

November 16, 2020

Study Record Updates

Last Update Posted (ACTUAL)

November 17, 2020

Last Update Submitted That Met QC Criteria

November 13, 2020

Last Verified

November 1, 2020

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • BBKeto

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

Subscribe