Cardiovascular Manifestations of COVID-19

Electronic medical record review of de-identified patients who tested positive for COVID-19 (using a PCR test) at Methodist Dallas Medical Center (MDMC) from June 2020 until the date of IRB approval. Data will be collected on de-identified patients that test positive for COVID-19 (using a PCR test) at MDMC from the date of IRB approval until December 2022. Disclaimer: Any cost associated with the procedures stated herein will be billed directly to you or to your insurance (as applicable)

Study Overview

• Status: Withdrawn
• Conditions: COVID-19
• Intervention / Treatment: Other: Chart review

Detailed Description

Electronic medical record review of de-identified patients who tested positive for COVID-19 (using a PCR test) at Methodist Dallas Medical Center (MDMC) from June 2020 until the date of IRB approval. Data will be collected on de-identified patients that test positive for COVID-19 (using a PCR test) at MDMC from the date of IRB approval until December 2022. Variables include patient baseline characteristics, patient presentation, imaging and labs. Disclaimer: Any cost associated with the procedures stated herein will be billed directly to you or to your insurance (as applicable)

• Study Type: Observational

Contacts and Locations

Study Locations

• United States
  • Texas
    • Dallas, Texas, United States, 75203
      • Methodist Dallas Medical Center

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years and older (Adult, Older Adult)
• Accepts Healthy Volunteers: N/A

• Sampling Method: Non-Probability Sample

Study Population

Patients that test positive for COVID-19 (using a PCR test) at MDMC

Description

Inclusion Criteria:

• Hospitalized patient
• Adult over 18 years
• Positive COVID-19 PCR Test

Exclusion Criteria:

• None

Study Plan

How is the study designed?

Design Details

• Observational Models: Cohort
• Time Perspectives: Other

Number of groups / cohorts

1

Cohorts and Interventions

Group / Cohort	Intervention / Treatment
Retrospective Cohort; Review electronic medical records of de-identified patients that tested positive for COVID-19 (using a PCR test) at Methodist Dallas Medical Center (MDMC) from June 2020 until December 2022	Other: Chart review; Chart review

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Heart failure	Presence or absence	March 2020 - June 2021
Tamponade	Presence or absence	March 2020 - June 2021
Pericardial Effusion	Presence or absence	March 2020 - June 2021
Myocarditis	Presence or absence	March 2020 - June 2021
Pericarditis	Presence or absence	March 2020 - June 2021
Arrythmias	Presence or absence	March 2020 - June 2021
Troponin I	Level	March 2020 - June 2021
N-terminal prohormone BNP	Level	March 2020 - June 2021

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Stroke	Presence or absence	March 2020 - June 2021
Myocardial infarction	Type	March 2020 - June 2021
Shock	Presence or absence	March 2020 - June 2021
Deep venous thrombosis	Presence or absence	March 2020 - June 2021
Discharge disposition	Location	March 2020 - June 2021
Primary diagnosis	Diagnosis upon discharge	March 2020 - June 2021
Rate of ICU admission/transfer	Rates	March 2020 - June 2021
Total hospital length of stay	Number of Days	March 2020 - June 2021
ICU length of stay	Number of Days	March 2020 - June 2021
Percentage of patients in cohort that had EKG testing or Echocardiography	Percentage	March 2020 - June 2021

Collaborators and Investigators

• Sponsor: Methodist Health System
• Investigators: Principal Investigator: Manavjot Sidhu, MD, Methodist Health System

Study record dates

Study Major Dates

• Study Start (Actual): March 21, 2023
• Primary Completion (Actual): July 3, 2023
• Study Completion (Actual): July 3, 2023

Study Registration Dates

• First Submitted: September 22, 2020
• First Submitted That Met QC Criteria: January 6, 2021
• First Posted (Actual): January 8, 2021

Study Record Updates

• Last Update Posted (Actual): May 19, 2026
• Last Update Submitted That Met QC Criteria: May 15, 2026
• Last Verified: May 1, 2026

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Respiratory Tract Infections; Infections; RNA Virus Infections; Virus Diseases; Respiratory Tract Diseases; Lung Diseases; Pneumonia, Viral; Pneumonia; Coronavirus Infections; Coronaviridae Infections; Nidovirales Infections; COVID-19
• Other Study ID Numbers: 030.CVS.2020.D

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No