Observational Study of the Clinico-biological Evolution and Standard of Care Offered to Patients With Ebola Virus Disease (EVISTA)

March 23, 2021 updated by: Alliance for International Medical Action

This study highlighted the possibility, even in epidemic settings, of providing advanced supportive care for patients with VMEs. Indeed, while the prospect of offering any invasive medical care was widely discussed in 2014 in West Africa with the aim of limiting the exposure of caregivers, the epidemic of 2018-2019 has on the contrary seen the development of a number of medical care strategies, in parallel with the deployment of specific treatments. This study aims to describe a cohort of patients receiving this upgraded supportive care during the tenth epidemic in the DRC.

Study Overview

Status

Completed

Conditions

Ebola Virus Disease

Intervention / Treatment

Other: Standard of Care

Study Type

Observational

Enrollment (Actual)

711

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

Congo, The Democratic Republic of the
- Nord Kivu
  - Beni, Nord Kivu, Congo, The Democratic Republic of the
    - BENI ETC

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

ADULT
OLDER_ADULT
CHILD

Accepts Healthy Volunteers

Genders Eligible for Study

All

Sampling Method

Non-Probability Sample

Study Population

All patients with positive RT-PCR admitted in ETC's during the inclusion period were included in the study

Description

Inclusion Criteria:

Laboratory confirmed Ebola Virus Disease

Exclusion Criteria:

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Mortality Time Frame: Through the end of the hospitalization, with an average of 11 days	Any type mortality during hospitalization	Through the end of the hospitalization, with an average of 11 days

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Alliance for International Medical Action

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (ACTUAL)

August 1, 2018

Primary Completion (ACTUAL)

December 31, 2019

Study Completion (ACTUAL)

December 31, 2019

Study Registration Dates

First Submitted

March 17, 2021

First Submitted That Met QC Criteria

March 23, 2021

First Posted (ACTUAL)

March 24, 2021

Study Record Updates

Last Update Posted (ACTUAL)