Post-traumatic Stress, Signs of Depression and Burnout Syndrome Among Nursing Home Staff in Occitanie During the COVID-19 Pandemic (PSY-COEHPAD-OC)

Stress Post Traumatique, Signes de dépression et Syndrome d'épuisement Professionnel Chez le Personnel Des EHPAD en Occitanie Pendant la pandémie COVID-19 : étude Prospective

Nursing home staff face multiple stresses during the Covid-19 pandemic including personal risk of infection, risk of transmission of the virus to residents and relatives, and risk of witnessing end-of-life scenarios under difficult contexts (absence of families). The hypothesis of this study is that the Covid-19 period is associated with an incidence of more than 30% of post-traumatic stress in nursing home staff.

Study Overview

• Status: Completed
• Conditions: Depressive Disorder; Covid19; Anxiety; Post Traumatic Stress Disorder; Substance Use Disorders
• Intervention / Treatment: Other: Cognitive tests

• Study Type: Observational
• Enrollment (Actual): 501

Contacts and Locations

Study Locations

• France
  • Montpellier, France
    • CHU de Montpellier
  • Nîmes, France, 30029
    • CHU de Nîmes, Hôpital Universitaire Carémeau
  • Toulouse, France
    • CHU de Toulouse

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years and older (Adult, Older Adult)
• Accepts Healthy Volunteers: Yes

• Sampling Method: Non-Probability Sample

Study Population

Professionasl working in a nursing home in Occitanie

Description

Inclusion Criteria:

• Professional working in a nursing home in Occitanie
• Professional agreeing to participate
• Professional in a nursing home for at least 3 months
• Professional able to read French
• Profession with an internet connection

Exclusion Criteria:

• The subject is in a period of exclusion determined by a previous study
• The subject refuses to participate
• The subject has already been included into the study
• It is impossible to give the subject informed information
• The subject is under safeguard of justice or state guardianship
• The subject is unable to express consent

Study Plan

How is the study designed?

Number of groups / cohorts

1

Cohorts and Interventions

Group / Cohort	Intervention / Treatment
Staff working in a nursing home in Occitanie	Other: Cognitive tests; Optional tests: Corsi block-tapping task, Stroop test and Iowa gambling task

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
To assess the prevalence of post-traumatic stress disorder (PTSD) in the context of the COVID-19 health crisis	Posttraumatic Stress Disorder Checklist Scale (PCL-5) scale, where the recommended cut-off threshold for screening is 44	Day 0

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Prevalence of depression in the context of the COVID-19 health crisis	Hospital Anxiety and Depression Scale (HADS) scale, using a cut-off above 7	Day 0
Prevalence of burn out in the context of the COVID-19 health crisis	Masslach Burn out Inventory (MBI) questionnaire where high scores for the professional burnout and depersonalization sections and a low score for the personal accomplishments section will signal burn out	Day 0

Other Outcome Measures

Outcome Measure	Measure Description	Time Frame
Optional assessment of work memory abnormalities associated with symptoms of post-traumatic stress disorder, anxiety and depression	Corsi block-tapping task - score ranging from 0(good memory) -18(bad memory)	Day 0
Optional assessment of cognitive flexibility abnormalities associated with symptoms of post-traumatic stress disorder, anxiety and depression	Corsi block-tapping task - score ranging from 0(good memory) -18(bad memory)	Day 0
Optional assessment of decision-making abnormalities associated with symptoms of post-traumatic stress disorder, anxiety and depression	Iowa Gambling Task - score ranes from -14 to +40	Day 0

Collaborators and Investigators

• Sponsor: Centre Hospitalier Universitaire de Nīmes
• Investigators: Principal Investigator: Ismaël Conejero, CHU de Nîmes

Publications and helpful links

General Publications

• Conejero I, Petrier M, Fabbro Peray P, Voisin C, Courtet P, Potier H, Elotmani L, Lafont B, Lefrant JY, Lopez Castroman J, Arbus C, Blain H. Post-traumatic stress disorder, anxiety, depression and burnout in nursing home staff in South France during the COVID-19 pandemic. Transl Psychiatry. 2023 Jun 15;13(1):205. doi: 10.1038/s41398-023-02488-1.

Study record dates

Study Major Dates

• Study Start (Actual): May 27, 2021
• Primary Completion (Actual): October 11, 2021
• Study Completion (Actual): October 11, 2021

Study Registration Dates

• First Submitted: June 4, 2021
• First Submitted That Met QC Criteria: June 4, 2021
• First Posted (Actual): June 7, 2021

Study Record Updates

• Last Update Posted (Estimated): December 4, 2025
• Last Update Submitted That Met QC Criteria: November 26, 2025
• Last Verified: October 1, 2021

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Trauma and Stressor Related Disorders; Mental Disorders; Respiratory Tract Infections; Infections; RNA Virus Infections; Virus Diseases; Respiratory Tract Diseases; Lung Diseases; Chemically-Induced Disorders; Mood Disorders; Pneumonia, Viral; Pneumonia; Coronavirus Infections; Coronaviridae Infections; Nidovirales Infections; Stress Disorders, Traumatic; COVID-19; Anxiety Disorders; Depressive Disorder; Substance-Related Disorders; Stress Disorders, Post-Traumatic; Behavioral Disciplines and Activities; Psychological Tests; Neuropsychological Tests
• Other Study ID Numbers: Local/2020/COVID/JYL IC-04; 2020-A03541-38 (Other Identifier: ANSM)

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No