Ventilatory Functions, Oxygen Saturation, and Quality of Life Response to Long Time Cement Dust Exposure

Thousands of people are working daily in a dusty environment. Many studied reported respiratory symptoms and ventilatory disorders among Factory workers who exposed to cement dust. But the evidence for respiratory effect and daily activities over a long time of cement dust exposure has not been conclusive

Study Overview

• Status: Completed
• Conditions: Occupational Diseases
• Intervention / Treatment: Diagnostic test: questionaire and ventilatory function test

Detailed Description

A total of 49 subjects working in a cement production factory were assessed and divided into three groups according to the total period of work exposure. Groupe A (18 subjects) with work period < 10 years, group B (13 subjects) with work period 10-15 years, group C (18 subjects) with work period > 15 years. The ventilatory functions, oxygen saturation, and quality of life were assessed in the three groups. RESULTS: The study results revealed a statistically significant difference between the three groups in the mean values of FVC (%), FEV1/FVC (%), SPO2.

• Study Type: Observational
• Enrollment (Actual): 49

Contacts and Locations

Study Locations

• Egypt
  • Cairo, Egypt
    • Faculty of Physical Therapy Cairo University

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 25 years to 50 years (Adult)
• Accepts Healthy Volunteers: N/A
• Genders Eligible for Study: Male

• Sampling Method: Probability Sample

Study Population

Out of sixty persons who were assigned to this study, a total of 49 subjects (group 1 n = 18, group 2 n = 13 and group 3 n = 18) completed the study (Fig. 1).

In all groups, A, B and, C; height and weight scale were obtained for calculating BMI. The distribution of smokers between different age groups was measured (table ) The pulmonary function tests were performed to evaluate the capacity and volume of the lungs among the participants. Spirometry measurements, including FVC, FEV1, ratio of FEV1 to FVC (FEV1/FVC), forced expiratory flow 25-75% (FEF 25-75%), and peak expiratory flow (PEF

Description

Inclusion Criteria:

• The ages were between 25 to 50 years old.
• the body mass index ranged from (18,5 - 29,9) kg/m2.

Exclusion Criteria:

• Age less than 25 or more 50.
• Any chronic diseases
• severe musculoskeletal and cardiopulmonary disorders and
• Class III Obesity (35-39.9 kg/m 2) or more

Study Plan

How is the study designed?

Number of groups / cohorts

3

Cohorts and Interventions

Group / Cohort	Intervention / Treatment
less than 10 years working; workers who work in cement factories in a period of time less than 10 years	Diagnostic test: questionaire and ventilatory function test; we assessed the arterial blood gases and the ventilatory functions and quality of life of whole three groups
from 10-15 years working; workers who work in cement factories in a period of time from 10-15 years	Diagnostic test: questionaire and ventilatory function test; we assessed the arterial blood gases and the ventilatory functions and quality of life of whole three groups
more than 15 years working; workers who work in cement factories in a period of time more than 15 years	Diagnostic test: questionaire and ventilatory function test; we assessed the arterial blood gases and the ventilatory functions and quality of life of whole three groups

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
The ventilatory functions	ventilatory function tests were used to assess FVC (%), FEV1/FVC (%),PEF (%), FEV1 (%)	8 months
oxygen saturation	measuring oxygen saturation using SPo2	8 months
quality of life were assessed	the mean values of the physical functioning item and energy/fatigue item in the quality of life questionnaire	8 months

Collaborators and Investigators

• Sponsor: Cairo University

Study record dates

Study Major Dates

• Study Start (Actual): May 1, 2018
• Primary Completion (Actual): March 5, 2019
• Study Completion (Actual): May 29, 2019

Study Registration Dates

• First Submitted: September 4, 2020
• First Submitted That Met QC Criteria: September 11, 2021
• First Posted (Actual): September 17, 2021

Study Record Updates

• Last Update Posted (Actual): September 17, 2021
• Last Update Submitted That Met QC Criteria: September 11, 2021
• Last Verified: September 1, 2021

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Occupational Diseases
• Other Study ID Numbers: Cairo

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No