Neopterin in Acute Coronary Syndrome Patients

Measurement of neopterin in ACS patients

Study Overview

• Status: Recruiting
• Conditions: Neopterin in Acute Coronary Syndrome Patients
• Intervention / Treatment: Other: Blood sample

Detailed Description

1. Detect level of neopterin in ACS patients to detect whether there is relation or not between ACS and neopterin
2. Detection of relation between neopterin and cardiac enzymes as CK and troponine in ACS patients
3. Detect relation between neopterin level and in hospital events

• Study Type: Observational
• Enrollment (Anticipated): 50

Contacts and Locations

• Study Contact: Name: Mina Khairy Alyshaa Gorgy, Resident; Phone Number: 01227386406; Email: Minakhairy1995@gmail.com
• Study Contact Backup: Name: Yehia Taha keshik, Prof. Doctor; Phone Number: 01223971269

Study Locations

• Egypt
  • Assiut, Egypt, AssiutU
    • Recruiting
    • Assiut University
    • Contact: Yehia Taha keshik, Prof . Doctor; Phone Number: 01223971269
    • Contact: Magdy Ibrahim El desoky, Lecturer; Phone Number: 01279950400

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years to 90 years (Adult, Older Adult)
• Accepts Healthy Volunteers: N/A
• Genders Eligible for Study: All

• Sampling Method: Non-Probability Sample

Study Population

All patients of sample size admitted to cardiology department with ACS.

Description

Inclusion Criteria:

• All patient of sample size admitted to cardiology departmentof Assiut university hospital with :

  1. Acute typical chest pain
  2. Positive cardiac enzymes
  3. ECG show recent ischemic changes
  4. ECHO show SWMA

Exclusion Criteria:

1. Patients not fulfill inclusion criteria.
2. Patients with other diseases which may cause increase of neopterin level as viral infections, intracellular bacteria or parasites infections, certain malignancies, allograft rejection

Study Plan

How is the study designed?

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
To detect whether there is association between neopterin and ACS or not	To detect whether there is association between neopterin and ACS or not	72 hours

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Detection of relation between neopterin and cardiac enzymes as CK and troponine in ACS and detection of relation between neopterin level and in hospital events	Detection of relation between neopterin and cardiac enzymes as CK and troponine in ACS and detection of relation between neopterin level and in hospital events	72 hours

Collaborators and Investigators

• Sponsor: Assiut University
• Investigators: Principal Investigator: Magdy Ibrahim Aldesowky, Lecturer, Assiut University

Study record dates

Study Major Dates

• Study Start (Anticipated): November 1, 2022
• Primary Completion (Anticipated): October 1, 2023
• Study Completion (Anticipated): October 1, 2024

Study Registration Dates

• First Submitted: October 5, 2021
• First Submitted That Met QC Criteria: October 5, 2021
• First Posted (Actual): October 15, 2021

Study Record Updates

• Last Update Posted (Actual): February 15, 2022
• Last Update Submitted That Met QC Criteria: February 14, 2022
• Last Verified: October 1, 2021

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Pathologic Processes; Myocardial Ischemia; Heart Diseases; Cardiovascular Diseases; Vascular Diseases; Disease; Syndrome; Acute Coronary Syndrome
• Other Study ID Numbers: Neopterin

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: UNDECIDED
• IPD Plan Description: Share if participants agree

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No