Natural Cycle, Minimal Stimulation and Conventional IVF: a Registry-based Study (IVF-Regsitry)

May 12, 2023 updated by: Magaton Isotta, Universitätsklinik fur Frauenheilkunde, Inselspital Bern

Natural Cycle, Minimal Stimulation and Conventional IVF: a Registry-based Comparison of the IVF Treatments, Their Efficacy and Pregnancy Outcomes

International prospective registry-based study of different types of In Vitro Fertilisation (IVF) and their outcome.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Detailed Description

One year of prospective collection of descriptive In-Vitro-Fertilisation data. The data will be collected in 13 In-Vitro-Fertilisation-centres

Study Type

Observational

Enrollment (Actual)

3000

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Switzerland
      • Bern, Switzerland, 3000
        • Universitätsfrauenklinik Bern

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Child
  • Adult
  • Older Adult

Accepts Healthy Volunteers

No

Sampling Method

Non-Probability Sample

Study Population

Patients aiming to do In Vitro Fertilisation with fresh embryo transfer

Description

Inclusion criteria: In Vitro Fertilisation and signed informed consent

Exclusion criteria:

  • Medical freezing
  • Social freezing
  • thawed cycles

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

Cohorts and Interventions

Group / Cohort
Intervention / Treatment
In Vitro Fertilisation (IVF)-Patients
Patients aim to do In-Vitro-Fertilisation (IVF)
Procedure: In Vitro Fertilisation (IVF)
Natural Cycle In Vitro Fertilisation (IVF): without hormonal stimulation Conventional In Vitro Fertilisation (IVF): conventional hormonal stimulation Minimal Stimulation In Vitro Fertilisation (IVF): low dose of hormonal stimulation will be applied

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Implantation rate
Time Frame: 1 year
pregnancy rate per transferred embryo
1 year

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Number of oocytes
Time Frame: 1 Year
Number of retrieved oocytes per protocol
1 Year
Clinical pregnancy rate
Time Frame: 1 year
Pregnancy rate per transfer
1 year
Pregnancy outcome
Time Frame: 1 year
Pregnancy complications including preeclampsia
1 year
In Vitro Fertilisation complications rates
Time Frame: 1 year
miscarriage
1 year

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Universitätsklinik fur Frauenheilkunde, Inselspital Bern

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

January 1, 2022

Primary Completion (Actual)

March 31, 2023

Study Completion (Actual)

March 31, 2023

Study Registration Dates

First Submitted

November 3, 2021

First Submitted That Met QC Criteria

November 17, 2021

First Posted (Actual)

November 18, 2021

Study Record Updates

Last Update Posted (Actual)

May 15, 2023

Last Update Submitted That Met QC Criteria

May 12, 2023

Last Verified

May 1, 2023

More Information

Terms related to this study

Other Study ID Numbers

  • 2021-01689 (BASEC-ID)
  • LB1562_NC-IVF (Other Identifier: RedCap ID)
  • Study Number 4949 (Other Identifier: Department Lehre und Forschung Inselspital Bern)

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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