Dietary Advanced Glycation End Products and Migraine

Are Dietary Intake of Advanced Glycation End Products and Migraine Associated? A Case-control Study

Is dietary intake of advanced glycation different between individuals with and without migraine? Is there a difference between the groups in terms of energy and nutrients? The answers to these questions are sought.

Study Overview

• Status: Completed
• Conditions: Nutrition Disorders; Migraine Disorders
• Intervention / Treatment: Other

• Study Type: Observational
• Enrollment (Actual): 120

Contacts and Locations

Study Locations

• Turkey
  • Karabük, Turkey, 78050
    • Karabuk University

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years to 64 years (Adult)
• Accepts Healthy Volunteers: Yes

• Sampling Method: Non-Probability Sample

Study Population

Adult individuals aged 19-64 who applied to Karabuk University Training and Research Hospital Neurology Clinic Headache Outpatient Clinic

Description

Inclusion Criteria:

• To be diagnosed with episodic migraine by an experienced neurologist,
• For the control group, patients who were not diagnosed with migraine but applied to the headache outpatient clinic
• Volunteer

Exclusion Criteria:

• Being younger than 19 years and older than 64 years of age, having a history of cardiovascular disease, hypertension, diabetes, cancer, liver and kidney disease or other neurological disorder (epilepsy, multiple sclerosis, stroke, traumatic brain injury, etc.), secondary headache, antilipidemic and glucose taking intolerance medications or vitamin-mineral supplements, following a special diet, and consuming less than 800 kcal or more than 4000 kcal per day

Study Plan

How is the study designed?

Number of groups / cohorts

2

Cohorts and Interventions

Group / Cohort
Migraine
Without Migraine

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Difference in dietary advanced glycation end products intake between groups	Is there a difference between the dietary intake of advanced glycation end products in individuals with migraine and healthy individuals? These values will be obtained from the food consumption records of the individuals. Intake of advanced glycation end product will be evaluated as ....kU/day. Is there a difference between the energy and nutrient intake of individuals with migraine and healthy individuals?	2 months

Collaborators and Investigators

• Sponsor: Karabuk University

Study record dates

Study Major Dates

• Study Start (Actual): February 1, 2022
• Primary Completion (Actual): September 1, 2022
• Study Completion (Actual): March 1, 2023

Study Registration Dates

• First Submitted: February 16, 2023
• First Submitted That Met QC Criteria: February 26, 2023
• First Posted (Actual): February 28, 2023

Study Record Updates

• Last Update Posted (Actual): May 25, 2023
• Last Update Submitted That Met QC Criteria: May 24, 2023
• Last Verified: February 1, 2023

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Pathologic Processes; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Headache Disorders, Primary; Headache Disorders; Disease; Migraine Disorders; Nutrition Disorders
• Other Study ID Numbers: Busra Demirer

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No