Correlation of Structure and Function in Glaucoma

November 24, 2025 updated by: Prim. Univ.-Prof. Dr. Pia Veronika Vécsei-Marlovits, MSc, MB, Vienna Hospital Association
The aim of the study is to correlate structure and function in patients with glaucoma. To this end, a cross-sectional study unsing perimetry and optical coherence tomography is performed.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Study Type

Observational

Enrollment (Actual)

60

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Austria
    • Vienna
      • Vienna, Vienna, Austria, 1130
        • Department of Ophthalmology, Clinic Hietzing, Vienna Healthcare Group

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult
  • Older Adult

Accepts Healthy Volunteers

No

Sampling Method

Non-Probability Sample

Study Population

Patients in the Department of Ophthalmology, Clinic Hietzing, Vienna Healthcare Group, who have been diagnosed with "glaucomatous optic neuropathy" are eligible for inclusion in the study.

Description

Inclusion Criteria:

- Diagnosis of glaucomatous optic neuropathy

Exclusion Criteria:

  • Age < 18 years
  • Diabetes
  • Pregnancy
  • Hypertensive retinopathy
  • Smoking
  • Intraocular surgery 1 month prior to study entry
  • Systemic or ocular disease, excluding glaucoma, which the investigator believes could affect the test results
  • Insufficient quality of the optical coherence tomography imaging
  • Insufficient cooperation during examinations or measurements

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Time Frame
Association of retinal sensitivity with peripapillary retinal nerve fiber layer thickness
Time Frame: 1 day
1 day
Association of retinal sensitivity with peripapillary vessel density
Time Frame: 1 day
1 day

Secondary Outcome Measures

Outcome Measure
Time Frame
Glaucoma Activity Limitation score
Time Frame: 1 day
1 day

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Vienna Hospital Association

Investigators

  • Principal Investigator: Pia V Vécsei-Marlovits, MD, MSc, MBA, Department of Ophthalmology, Clinic Hietzing, Vienna Healthcare Group

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

July 1, 2023

Primary Completion (Actual)

December 31, 2024

Study Completion (Actual)

December 31, 2024

Study Registration Dates

First Submitted

July 10, 2023

First Submitted That Met QC Criteria

July 10, 2023

First Posted (Actual)

July 20, 2023

Study Record Updates

Last Update Posted (Actual)

December 2, 2025

Last Update Submitted That Met QC Criteria

November 24, 2025

Last Verified

November 1, 2025

More Information

Terms related to this study

Additional Relevant MeSH Terms

Other Study ID Numbers

  • struct_funct_glaucoma

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

UNDECIDED

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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