Correlation of Structure and Function in Glaucoma
November 24, 2025 updated by: Prim. Univ.-Prof. Dr. Pia Veronika Vécsei-Marlovits, MSc, MB, Vienna Hospital Association
The aim of the study is to correlate structure and function in patients with glaucoma.
To this end, a cross-sectional study unsing perimetry and optical coherence tomography is performed.
Study Overview
Study Type
Observational
Enrollment (Actual)
60
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
-
-
Vienna
-
Vienna, Vienna, Austria, 1130
- Department of Ophthalmology, Clinic Hietzing, Vienna Healthcare Group
-
-
Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
- Adult
- Older Adult
Accepts Healthy Volunteers
No
Sampling Method
Non-Probability Sample
Study Population
Patients in the Department of Ophthalmology, Clinic Hietzing, Vienna Healthcare Group, who have been diagnosed with "glaucomatous optic neuropathy" are eligible for inclusion in the study.
Description
Inclusion Criteria:
- Diagnosis of glaucomatous optic neuropathy
Exclusion Criteria:
- Age < 18 years
- Diabetes
- Pregnancy
- Hypertensive retinopathy
- Smoking
- Intraocular surgery 1 month prior to study entry
- Systemic or ocular disease, excluding glaucoma, which the investigator believes could affect the test results
- Insufficient quality of the optical coherence tomography imaging
- Insufficient cooperation during examinations or measurements
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Time Frame |
|---|---|
|
Association of retinal sensitivity with peripapillary retinal nerve fiber layer thickness
Time Frame: 1 day
|
1 day
|
|
Association of retinal sensitivity with peripapillary vessel density
Time Frame: 1 day
|
1 day
|
Secondary Outcome Measures
Outcome Measure |
Time Frame |
|---|---|
|
Glaucoma Activity Limitation score
Time Frame: 1 day
|
1 day
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Sponsor
Investigators
- Principal Investigator: Pia V Vécsei-Marlovits, MD, MSc, MBA, Department of Ophthalmology, Clinic Hietzing, Vienna Healthcare Group
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start (Actual)
July 1, 2023
Primary Completion (Actual)
December 31, 2024
Study Completion (Actual)
December 31, 2024
Study Registration Dates
First Submitted
July 10, 2023
First Submitted That Met QC Criteria
July 10, 2023
First Posted (Actual)
July 20, 2023
Study Record Updates
Last Update Posted (Actual)
December 2, 2025
Last Update Submitted That Met QC Criteria
November 24, 2025
Last Verified
November 1, 2025
More Information
Terms related to this study
Additional Relevant MeSH Terms
Other Study ID Numbers
- struct_funct_glaucoma
Plan for Individual participant data (IPD)
Plan to Share Individual Participant Data (IPD)?
UNDECIDED
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
No
Studies a U.S. FDA-regulated device product
No
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.