Optimal Incision Site Design for Lymphaticovenular Anastomosis in Extremity Lymphedema

Optimal Incision Site Design for Lymphaticovenular Anastomosis in Extremity

Our aim was to identify optimal incision sites for LVA in extremity lymphedema that would result in the most effective drainage effect for reducing limb edema and enhancing patients' quality of life.

Study Overview

• Status: Completed
• Conditions: Lymphedema

Detailed Description

designing the optimal incision sites and identifying functional lymphatic vessels imaging is crucial for success, primarily due to its efficacy in draining edematous lymphatic fluid and reducing swelling in patients with lymphedema. In this study, we conducted patients with LVA lymphedema to investigate the correlation between LVA incision design, intraoperative functional lymphatic vessel assessment, postoperative limb reduction, and patient satisfaction.

question 1：Optimal Incision Site Design for Lymphaticovenular Anastomosis in Extremity lymphedema

• Study Type: Observational
• Enrollment (Actual): 267

Contacts and Locations

Study Locations

• China
  • Zhejiang, China, 318000
    • Chong Liu

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Adult; Older Adult
• Accepts Healthy Volunteers: N/A

• Sampling Method: Non-Probability Sample

Study Population

Lymphedema patients

Description

Inclusion Criteria: Aged 18-80 years; Lymphedema and swelling of the limbs for more than 3 months

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Exclusion Criteria:

• lipedema；myoedema

Study Plan

How is the study designed?

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Number of Participants with lymphedema stage	stage 0-3	through study completion, an average of 4 year
Number of Optimal Incision Site Design	Optimal Incision Site Design for Lymphaticovenular Anastomosis	through study completion, an average of 4 year
Rate of lymphatic vessel Functional Parameters	intraoperative functional lymphatic vessel assessment	through study completion, an average of 4 year
Circumferential Reduction rate	postoperative limb reduction and patient satisfaction	through study completion, an average of 4 year

Collaborators and Investigators

• Sponsor: Taizhou Hospital
• Investigators: Study Director: yomao zheng, Employee; Principal Investigator: chong liu, Employee

Study record dates

Study Major Dates

• Study Start (Actual): January 1, 2020
• Primary Completion (Actual): December 1, 2023
• Study Completion (Actual): December 1, 2023

Study Registration Dates

• First Submitted: December 10, 2023
• First Submitted That Met QC Criteria: December 18, 2023
• First Posted (Actual): January 3, 2024

Study Record Updates

• Last Update Posted (Actual): January 3, 2024
• Last Update Submitted That Met QC Criteria: December 18, 2023
• Last Verified: December 1, 2023

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Lymphatic Diseases; Lymphedema
• Other Study ID Numbers: Taizhou Hospital OISD

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No