Effects of Physical Fatigue on Cognitive Load and Performance Under Dual-Task Environments.

April 24, 2025 updated by: Riphah International University

To Determine the Effects of Physical Fatigue on Cognitive Load and Performance Under Dual-Task Environments.

This study aims to determine how different levels of physical fatigue influence cognitive load and performance during dual-task activities.

  1. To assess the changes in cognitive task performance under varying levels of physical fatigue.
  2. There is an association between cognitive loading and physical fatigue.

Study Overview

Detailed Description

Working efficiency in our daily routine is hindered by constant change, urgency, and the demands of sustained efforts, all of which contribute to health and safety problems, and are extremely imprudent of human resources in the workplace, due to which individuals would raise anxiety, causing more attention required for task completion and thereby increasing cognitive load. Cognitive loading refers to the mental effort needed to process information and perform tasks. Physical performance is not only related to physical factors, psychological factors also have the potential to determine physical performance. Mental workload is defined as the difference between the cognitive demand of a particular task and the operator's attention resources. When cognitive demands exceed available resources, mental fatigue can occur, often reflected in decreased motor function and impaired physical performance. Fatigue is recognized as a dimensional phenomenon encompassing cognitive and motor fatigue. It is debatable whether cognitive fatigue is a spontaneous phenomenon or provoked by exertion or whether cognitive fatigue is provoked by cognitive effort or also through physical exercise. Physical fatigue develops more quickly when the brain has to devote resources to highly cognitive tasks. Influence of cognitive load on the dynamics of neurophysiological adjustments during exercise which causes fatigue explained by the interaction of various psychological and neurophysiological factors including higher perceived exertion, greater perturbations of autonomic nervous system activity, and cerebral impairments leading to earlier onset of central fatigue. The brain is like other biological tissue tired out when overused. Since the impact of physical exercise on cognitive functioning is dependent on the characteristics of the physical exercise load. Previous research has demonstrated a small-to-medium negative effect of cognitive exertion on subsequent physical performance. Our study aims to explore the interplay between varying levels of physical fatigue and cognitive performance. Specifically, we will examine how different intensities of physical load affect mental load and associated physiological functions. By investigating these relationships, we seek to provide insights into optimizing performance in dual-task environments, ultimately contributing to better health and efficiency in the workplace.

Study Type

Interventional

Enrollment (Estimated)

90

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

Study Locations

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult

Accepts Healthy Volunteers

Yes

Description

Inclusion Criteria:

  • Individuals aged 18 to 30 years.
  • Physically healthy individuals.
  • Willingness to participate in the study.

Exclusion Criteria:

  • Cognitive Impairment.
  • Neurological injury.
  • Cardiac, pulmonary, or inflammatory diseases.
  • Mental health conditions include depression and post-traumatic stress disorder.
  • Individuals unwilling to participate.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Health Services Research
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: Triple

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: Group 1
Participants with a target Heart rate range of 50-60% of their maximum heart rate. All members of Group 1 who meet the eligibility criteria will perform a cognitive task before undergoing mild-intensity physical fatigue induced by treadmill training. After that participants will complete the cognitive task again. To eliminate bias, three different levels of physical exertion will be randomly assigned.
Participants will undergo mild-intensity physical fatigue through a structured treadmill training protocol. The training will be conducted within a target heart rate range of 50-60% of their maximum heart rate (HRmax), ensuring controlled and consistent exercise intensity. This approach aims to induce mild physiological stress while maintaining safety and feasibility for all participants.
Experimental: Group 2
Participants with a target Heart rate range of 60-70% of their maximum heart rate. All members of group 2 who meet the eligibility criteria will perform a cognitive task before undergoing moderate-intensity physical fatigue induced by treadmill training. After that participants will complete the cognitive task again. To eliminate bias, three different levels of physical exertion will be randomly assigned.
Participants will undergo Moderate-intensity physical fatigue through a structured treadmill training protocol. The training will be conducted within a target heart rate range of 60-70% of their maximum heart rate (HRmax), ensuring controlled and consistent exercise intensity. This approach aims to induce mild physiological stress while maintaining safety and feasibility for all participants.
Experimental: Group 3
Participants with a target Heart rate range of 70-80% of their maximum heart rate. All members of group 3 who meet the eligibility criteria will perform a cognitive task before undergoing high-intensity physical fatigue induced by treadmill training. After that participants will complete the cognitive task again. To eliminate bias, three different levels of physical exertion will be randomly assigned.
Participants will undergo High-intensity physical fatigue through a structured treadmill training protocol. The training will be conducted within a target heart rate range of 70-80% of their maximum heart rate (HRmax), ensuring controlled and consistent exercise intensity. This approach aims to induce sufficient physiological stress while maintaining safety and feasibility for all participants.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Heart rate variability
Time Frame: Baseline
An electrocardiogram (ECG) will be utilized to assess heart rate variability, which will measure the fluctuations in time between heartbeats. Low heart rate variability will indicate increased cognitive load.
Baseline
Heart rate variability (2nd reading)
Time Frame: Periprocedural
An electrocardiogram (ECG) will be utilized to assess heart rate variability, which will measure the fluctuations in time between heartbeats. Low heart rate variability will indicate increased cognitive load. 2nd reading will be measured during the cognitive task (without physical fatigue).
Periprocedural
Heart rate variability (3rd reading)
Time Frame: Periprocedural
An electrocardiogram (ECG) will be utilized to assess heart rate variability, which will measure the fluctuations in time between heartbeats. Low heart rate variability will indicate increased cognitive load. 3rd reading will be measured after the cognitive task (without physical fatigue).
Periprocedural
Heart rate variability (4rth reading)
Time Frame: Periprocedural
An electrocardiogram (ECG) will be utilized to assess heart rate variability, which will measure the fluctuations in time between heartbeats. Low heart rate variability will indicate increased cognitive load. 4rth reading will be measured after physical fatigue.
Periprocedural
Heart rate variability (5th reading)
Time Frame: Periprocedural
An electrocardiogram (ECG) will be utilized to assess heart rate variability, which will measure the fluctuations in time between heartbeats. Low heart rate variability will indicate increased cognitive load. The 5th reading will be measured during the cognitive task after physical fatigue.
Periprocedural
Heart rate variability (6th reading)
Time Frame: Periprocedural
An electrocardiogram (ECG) will be utilized to assess heart rate variability, which will measure the fluctuations in time between heartbeats. Low heart rate variability will indicate increased cognitive load. The 6th reading will be measured after the cognitive task, after physical fatigue.
Periprocedural
Galvanic skin response
Time Frame: Baseline
The electrical conductance of the skin, measured by Galvanic Skin Response (GSR), will be influenced by moisture levels resulting from sweat gland activity. A high GSR will typically indicate an increased cognitive load.
Baseline
Galvanic skin response (2nd reading)
Time Frame: Periprocedural
The electrical conductance of the skin, measured by Galvanic Skin Response (GSR), will be influenced by moisture levels resulting from sweat gland activity. A high GSR will typically indicate an increased cognitive load. 2nd reading will be measured during the cognitive task (without physical fatigue).
Periprocedural
Galvanic skin response (3rd reading)
Time Frame: Periprocedural
The electrical conductance of the skin, measured by Galvanic Skin Response (GSR), will be influenced by moisture levels resulting from sweat gland activity. A high GSR will typically indicate an increased cognitive load. 3rd reading will be measured after the cognitive task (without physical fatigue).
Periprocedural
Galvanic skin response (4rth reading)
Time Frame: Periprocedural
The electrical conductance of the skin, measured by Galvanic Skin Response (GSR), will be influenced by moisture levels resulting from sweat gland activity. A high GSR will typically indicate an increased cognitive load.4rth reading will be measured after physical fatigue.
Periprocedural
Galvanic skin response (5th reading)
Time Frame: Periprocedural
The electrical conductance of the skin, measured by Galvanic Skin Response (GSR), will be influenced by moisture levels resulting from sweat gland activity. A high GSR will typically indicate an increased cognitive load. The 5th reading will be measured during the cognitive task after physical fatigue.
Periprocedural
Galvanic skin response (6th reading)
Time Frame: Periprocedural
The electrical conductance of the skin, measured by Galvanic Skin Response (GSR), will be influenced by moisture levels resulting from sweat gland activity. A high GSR will typically indicate an increased cognitive load. The 6th reading will be measured after the cognitive task, after physical fatigue.
Periprocedural
Nasa task load index
Time Frame: Periprocedural
The different dimensions of task load, including mental demand, physical demand, temporal demand, performance, effort, and frustration, will be measured subjectively using the NASA Task Load Index (TLX). Low ratings will typically indicate an increased cognitive load. 1st reading will be taken after the cognitive task, before inducing physical fatigue.
Periprocedural
Nasa task load index (2nd reading)
Time Frame: Periprocedural
The different dimensions of task load, including mental demand, physical demand, temporal demand, performance, effort, and frustration, will be measured subjectively using the NASA Task Load Index (TLX). Low ratings will typically indicate an increased cognitive load. 2nd reading will be taken after the cognitive task, post physical fatigue induction.
Periprocedural
Borg scale of perceived exertion
Time Frame: Periprocedural
After achieving the mild intensity target heart rate range of 50-60% through treadmill training, the Borg Rate of Perceived Exertion (RPE) category scale (6-20) will be utilized to assess exertion levels. A higher score on this scale will indicate greater physical exertion.
Periprocedural
Borg scale of perceived exertion (Ist reading)
Time Frame: Periprocedural
Following the induction of physical fatigue, the Borg Rate of Perceived Exertion (RPE) category scale (6-20) will be used to evaluate exertion levels achieved during the treadmill training at the mild intensity target heart rate range of 50-60%. A higher score will reflect increased physical exertion. Ist reading will be taken after inducing physical fatigue.
Periprocedural
Borg scale of perceived exertion (2nd reading)
Time Frame: Periprocedural
After achieving the moderate intensity target heart rate range of 60-70% through treadmill training, the Borg Rate of Perceived Exertion (RPE) category scale (6-20) will be utilized to assess exertion levels. A higher score on this scale will indicate greater physical exertion. 2nd reading will be taken after the cognitive task prior to inducing physical fatigue.
Periprocedural
Borg scale of perceived exertion (3rd reading)
Time Frame: Periprocedural
Following the induction of physical fatigue, the Borg Rate of Perceived Exertion (RPE) category scale (6-20) will be used to evaluate exertion levels achieved during the treadmill training at the moderate intensity target heart rate range of 60-70%. A higher score will reflect increased physical exertion. 3rd reading will be taken after inducing physical fatigue.
Periprocedural
Borg scale of perceived exertion (4rth reading)
Time Frame: Periprocedural
After achieving the High-intensity target heart rate range of 70-80% through treadmill training, the Borg Rate of Perceived Exertion (RPE) category scale (6-20) will be utilized to assess exertion levels. A higher score on this scale will indicate greater physical exertion. 4rth reading will be taken after the cognitive task, before inducing physical fatigue.
Periprocedural
Borg scale of perceived exertion (5th reading)
Time Frame: Periprocedural
Following the induction of physical fatigue, the Borg Rate of Perceived Exertion (RPE) category scale (6-20) will be used to evaluate exertion levels achieved during the treadmill training at the High-intensity target heart rate range of 70-80%. A higher score will reflect increased physical exertion. 5th reading will be taken after inducing physical fatigue.
Periprocedural

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Investigators

  • Principal Investigator: Imran Amjad, Phd, Riphah International University

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

April 23, 2025

Primary Completion (Estimated)

July 30, 2025

Study Completion (Estimated)

July 30, 2025

Study Registration Dates

First Submitted

April 7, 2025

First Submitted That Met QC Criteria

April 22, 2025

First Posted (Actual)

April 24, 2025

Study Record Updates

Last Update Posted (Actual)

April 25, 2025

Last Update Submitted That Met QC Criteria

April 24, 2025

Last Verified

April 1, 2025

More Information

Terms related to this study

Additional Relevant MeSH Terms

Other Study ID Numbers

  • REC/02028 Imran Amjad

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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