- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT07420842
Influencer Marketing and Adolescent E-cigarette Use
February 11, 2026 updated by: Jennifer Unger, University of Southern California
The Effect of Social Media Influencer Marketing on E-cigarette Perceptions and Use by Adolescents.
Adolescents (N = 700) participated in the online survey-based randomized experiment focused on understanding youth perceptions of e-cigarette influencer marketing on social media.
Specifically, the study assessed how age appearance of social media influencers, fitness-related contextual framing of e-cigarette content, and perceived influencer credibility jointly shape adolescent harm perceptions, appeal, and susceptibility to e-cigarette use.
Participants were randomly shown 6 videos, featuring younger- or older-looking influencers promoting e-cigarettes in the following experimental conditions: 1) younger-looking influencers promoting e-cigarettes alongside fitness-oriented activities (condition 1); 2) older-looking influencers promoting e-cigarettes alongside fitness-oriented activities (condition 2); 3) younger-looking influencers promoting e-cigarettes without any fitness-oriented content; and 4) older-looking influencers promoting e-cigarettes without any fitness-oriented content (control).
After watching each video, participants rated perceptions of influencer credibility (i.e., honesty, trustworthiness, knowledge) on the scale of 0 (e.g., dishonest) to 100 (honest).
Among all participants, harm perceptions and appeal of e-cigarettes was also assessed.
Susceptibility to use e-cigarettes was assessed among never users of e-cigarettes.
Study Overview
Status
Completed
Conditions
Intervention / Treatment
Detailed Description
Adolescents (14-17 years of age) living in California were recruited by Qualtrics marketing research panel to participate in a survey on tobacco-related attitudes and behaviors.
Qualtrics, a research panel agency, has been used in prior research to survey adolescents about their tobacco-related attitudes and behaviors.
Participants were provided with a survey URL link.
After completing informed consent, participants completed the survey online.
The study was approved by the University of Southern California Institutional Review Board (UP-CG-24-00013).
Respondents were randomly assigned to watch six 10-second long Instagram and/or TikTok videos in four experimental conditions: 1) younger-looking influencers promoting e-cigarettes alongside fitness-oriented activities (condition 1); 2) older-looking influencers promoting e-cigarettes alongside fitness-oriented activities (condition 2); 3) younger-looking influencers promoting e-cigarettes without any fitness-oriented content; and 4) older-looking influencers promoting e-cigarettes without any fitness-oriented content (control).
Study Type
Interventional
Enrollment (Actual)
700
Phase
- Not Applicable
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
-
-
Washington
-
Seattle, Washington, United States, 98101
- Qualtrics, survey was administered online
-
-
Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
- Child
Accepts Healthy Volunteers
No
Description
Inclusion Criteria:
- 14-17 years of age,
- English fluency,
- Current California resident.
Exclusion Criteria:
Not meeting the following criteria:
- 14-17 years of age,
- English fluency,
- Current California resident.
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
- Primary Purpose: Other
- Allocation: Randomized
- Interventional Model: Factorial Assignment
- Masking: None (Open Label)
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
|---|---|
|
Experimental: Videos featuring young influencers promoting e-cigarettes alongside fitness-related activities
a 10 second video clip
|
Participants watched online survey-imbedded promotional videos featuring influencers.
Influencer age appearance was manipulated using AI-based age filter.
|
|
Experimental: Videos featuring older influencers promoting e-cigarettes alongside fitness-related activities
a 10 second video clip
|
Participants watched online survey-imbedded promotional videos featuring influencers.
Influencer age appearance was manipulated using AI-based age filter.
|
|
Experimental: Videos featuring young influencers promoting e-cigarettes without fitness-related activities
a 10 second video clip
|
Participants watched online survey-imbedded promotional videos featuring influencers.
Influencer age appearance was manipulated using AI-based age filter.
|
|
Active Comparator: Videos featuring older influencers promoting e-cigarettes without fitness-related activities
a 10 second video clip
|
Participants watched online survey-imbedded promotional videos featuring influencers.
Influencer age appearance was manipulated using AI-based age filter.
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
|---|---|---|
|
Harm Perceptions of e-cigarettes
Time Frame: assessed six times immediately after each of the six videos during the 15-minute-long survey-based experiment
|
Responses to one question adapted from PATH, "Based on the videos you just watched, do you think using e-cigarettes for vaping nicotine is harmful to your health?"
The outcome was assessed on the 5-point ordinal scale with the following response choices: Not at all harmful, slightly harmful, somewhat harmful, very harmful, extremely harmful.
|
assessed six times immediately after each of the six videos during the 15-minute-long survey-based experiment
|
|
Perceived appeal of e-cigarettes
Time Frame: Assessed six times immediately after each of the six videos during the 15-minute-long survey-based experiment
|
Description: Responses to the following questions: using e-cigarette is: not cool/cool, unattractive/attractive were assessed on the 7-point semantic differential scale with the word pairs anchored at each end.
The scale was adapted from prior research.
The items were combined (by summing all the non-missing values of the items) into one variable (α=0.94).
|
Assessed six times immediately after each of the six videos during the 15-minute-long survey-based experiment
|
|
Susceptibility to e-cigarette use
Time Frame: Assessed six times immediately after each of the six videos during the 15-minute-long survey-based experiment
|
Susceptibility to e-cigarette use was measured (among never-users of e-cigarettes), using the validated three-item scale (indicating peer influence, intention, and curiosity about e-cigarette use) adapted from PATH, and combined into one variable (α=0.93).
Consistent with prior research, the measure was dichotomized with responses "definitely not" to all items being coded as "not susceptible" and responses "probably not," "probably yes", or "definitely yes" being coded as "susceptible."
|
Assessed six times immediately after each of the six videos during the 15-minute-long survey-based experiment
|
|
Perceived influencer credibility
Time Frame: Assessed six times immediately after each of the six videos during the 15-minute-long survey-based experiment
|
Perceived influencer credibility (i.e., honesty, trustworthiness, knowledge) were assessed using a 0 (e.g., dishonest) -100 (e.g., honest) scale that has been validated in prior research.
|
Assessed six times immediately after each of the six videos during the 15-minute-long survey-based experiment
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Collaborators
Investigators
- Principal Investigator: Jennifer B Unger, PhD, University of Southern California
Publications and helpful links
The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.
Helpful Links
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start (Actual)
July 16, 2025
Primary Completion (Actual)
August 1, 2025
Study Completion (Actual)
August 1, 2025
Study Registration Dates
First Submitted
February 1, 2026
First Submitted That Met QC Criteria
February 11, 2026
First Posted (Actual)
February 19, 2026
Study Record Updates
Last Update Posted (Actual)
February 19, 2026
Last Update Submitted That Met QC Criteria
February 11, 2026
Last Verified
February 1, 2026
More Information
Terms related to this study
Plan for Individual participant data (IPD)
Plan to Share Individual Participant Data (IPD)?
NO
IPD Plan Description
survey is anonymous.
Data will be publicly available on GitHub repository if a manuscript related to this study is accepted for publication
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
No
Studies a U.S. FDA-regulated device product
No
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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