Oscillometry and Machine Learning Approaches

Feasibility Study of Forced Oscillometry in the Prediction of Chronic Respiratory Diseases Using Machine Learning Approaches

Unicentric retrospective study designed to analyses the performance of various machine learning approaches to predict patterns of chronic respiratory diseases such as asthma, based mainly on clinical information and respiratory spirometry/oscillometry.

Study Overview

• Status: Recruiting
• Conditions: Asthma COPD
• Intervention / Treatment: Other: 1

Detailed Description

Impulse oscillometry is a technique that allows evaluation of pulmonary mechanics through the application of sound waves of different frequencies, collecting the oscillations produced in the patient in response. The use of mathematical algorithms in the interpretation of oscillometry improves the evaluation of pulmonary function. The aim of the present study is to evaluate machine learning approaches to recognize respiratory patterns of different diseases.

• Study Type: Observational
• Enrollment (Estimated): 50

Contacts and Locations

• Study Contact: Name: Astrid Crespo, PhD; Phone Number: +34-935565972; Email: acrespo@santpau.cat
• Study Contact Backup: Name: Astrid Crespo-Lessmann, PhD; Phone Number: +34-935565972; Email: acrespo@santpau.cat

Study Locations

• Spain
  • Barcelona, Spain, 08041
    • Recruiting
    • Hospital De La Santa Creu I Sant Pau
    • Contact: Astrid Crespo Lessmann, MD; Phone Number: +34-935565972; Email: acrespo@santpau.cat

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Adult; Older Adult
• Accepts Healthy Volunteers: Yes

• Sampling Method: Non-Probability Sample

Study Population

Patients with asthma or COPD

Description

Inclusion Criteria:

• 18 - 90 years
• Spirometry available
• Confirmed clinical diagnosis of COPD, asthma, interstitial lung disease according to national or international guidelines

Exclusion Criteria:

• Acute respiratory infection

Study Plan

How is the study designed?

Number of groups / cohorts

1

Cohorts and Interventions

Group / Cohort	Intervention / Treatment
Oscillometry; Compare oscillometry results with spirometryClick to apply	Other: 1; Compare oscillometry results with spirometryClick to apply

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Oscillometric breathing pattern	Analyze results obtained	1 year

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Respiratory pattern spirometry	Forced expiratory volume in 1 second	1 year

Collaborators and Investigators

• Sponsor: Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
• Investigators: Principal Investigator: Astrid Crespo-Lessmann, PhD, Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau

Publications and helpful links

General Publications

• Oostveen E, MacLeod D, Lorino H, Farre R, Hantos Z, Desager K, Marchal F; ERS Task Force on Respiratory Impedance Measurements. The forced oscillation technique in clinical practice: methodology, recommendations and future developments. Eur Respir J. 2003 Dec;22(6):1026-41. doi: 10.1183/09031936.03.00089403.
• Komarow HD, Myles IA, Uzzaman A, Metcalfe DD. Impulse oscillometry in the evaluation of diseases of the airways in children. Ann Allergy Asthma Immunol. 2011 Mar;106(3):191-9. doi: 10.1016/j.anai.2010.11.011. Epub 2011 Jan 6.
• Bickel S, Popler J, Lesnick B, Eid N. Impulse oscillometry: interpretation and practical applications. Chest. 2014 Sep;146(3):841-847. doi: 10.1378/chest.13-1875.
• Schulz H, Flexeder C, Behr J, Heier M, Holle R, Huber RM, Jorres RA, Nowak D, Peters A, Wichmann HE, Heinrich J, Karrasch S; KORA Study Group. Reference values of impulse oscillometric lung function indices in adults of advanced age. PLoS One. 2013 May 15;8(5):e63366. doi: 10.1371/journal.pone.0063366. Print 2013.

Study record dates

Study Major Dates

• Study Start (Actual): October 15, 2025
• Primary Completion (Estimated): July 15, 2026
• Study Completion (Estimated): September 1, 2026

Study Registration Dates

• First Submitted: February 26, 2026
• First Submitted That Met QC Criteria: February 26, 2026
• First Posted (Actual): March 3, 2026

Study Record Updates

• Last Update Posted (Actual): March 3, 2026
• Last Update Submitted That Met QC Criteria: February 26, 2026
• Last Verified: February 1, 2026

More Information

Terms related to this study

• Other Study ID Numbers: IIBSP-MLA-2024-05

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: UNDECIDED

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No