Channelled Blade Versus Non-Channelled Videolaryngoscope

May 4, 2026 updated by: Yeoh Wei Yen, University of Malaya

Comparative Study of the Channelled Blade Astra-Vue Videolaryngoscope and the Non-Channelled CMAC D-Blade Videolaryngoscope in Airway Management: A Randomized Controlled Trial

The goal of this clinical trial is to learn if performance of a channelled blade Astra-Vue videolaryngoscope compared to non channelled hyperangulated C-MAC D-blade videolaryngoscope(Karl Storz, Tuttlingen, Germany) in airway management among adults undergoing elective surgery under general anesthesia. The main primary outcomes measured is the overall time taken to intubation, secondary measures includes the first attempt success rate, ease with intubation and associated complication

Participants are of adults who planned for elective or semi emergency surgery under general anesthesia. They will be screened and recruited with informed and written consent. Intubation information will be collected

Study Overview

Status

Active, not recruiting

Conditions

Intervention / Treatment

Detailed Description

This randomized controlled trial aims to compare the performance of a channelled videolaryngoscope (AstraVue videolaryngoscope) with a non-channelled hyperangulated videolaryngoscope (C-MAC™ D-Blade videolaryngoscope, Karl Storz, Tuttlingen, Germany) in adult patients undergoing elective or semi-emergency surgery under general anaesthesia requiring endotracheal intubation.

Participants will be randomly assigned to intubation using either the channelled AstraVue videolaryngoscope or the non-channelled C-MAC D-Blade videolaryngoscope. Standard anaesthesia induction protocols will be followed.

The primary outcome is the total time to successful intubation. Secondary outcomes include time to glottic visualization, time from glottic visualization to intubation, first-attempt success rate, number of attempts, need for external laryngeal manipulation, haemodynamic responses, and intubation-related complications.

Data will be collected prospectively during the peri-intubation period. The study aims to evaluate whether the channelled design improves intubation efficiency and success compared to the non-channelled videolaryngoscope.

Study Type

Interventional

Enrollment (Estimated)

60

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Malaysia
    • Kuala Lumpur
      • Petaling Jaya, Kuala Lumpur, Malaysia, 59100
        • Universiti Malaya Medical Centre

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult
  • Older Adult

Accepts Healthy Volunteers

Yes

Description

Inclusion Criteria:

  • Adult patients aged 18 to 70 years old requiring endotracheal intubation for elective or semi-emergency surgery under general anaesthesia
  • ASA I, II and stable ASA III patients
  • Patient with Mallampati Score Grade 1 to 3

Exclusion Criteria:

  • Patients with known airway abnormalities or anticipated difficult intubation,
  • Patients with desaturation before intubation,
  • Patients with high risk for aspiration requiring rapid sequence induction
  • Patient with known cervical pathology.
  • Patient refuse to participate

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: None (Open Label)

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: Channelled blade videolaryngoscope
Endotracheal intubation done with channelled blade videolaryngoscope
Device: channelled blade videolaryngoscope
Intubation with channelled blade videolaryngoscope
Active Comparator: Non channelled hyperangulated blade videolaryngoscope
Endotracheal intubation done with non channelled hyperangulated blade videolaryngoscope
Device: Non channelled hyperangulated blade videolaryngoscope
Intubation done by using Non channelled hyperangulated blade videolaryngoscope

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Total Time to intubation
Time Frame: During the intubation procedure (within minutes after induction of general anaesthesia)
time from insertion of laryngoscope blade through incisor teeth to visualization of Endotracheal tube into trachea, measured in seconds
During the intubation procedure (within minutes after induction of general anaesthesia)

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
First attempt success rate
Time Frame: During the intubation procedure(within minutes after induction of general anaesthesia)
Successful endotracheal intubation on the first attempt, measured as a proportion of total intubations(%)
During the intubation procedure(within minutes after induction of general anaesthesia)
Time to Glottic Visualization
Time Frame: During the intubation procedure(within minutes after induction of general anaesthesia)
time from insertion of laryngoscope blade to visualization of glottis, measured in seconds
During the intubation procedure(within minutes after induction of general anaesthesia)
Ease of intubation
Time Frame: During the intubation procedure an immediate post-intubation period (within minutes after induction of general anaesthesia)
Ease of intubation assessed using a modified Intubation Difficulty Scale (IDS), which includes parameters such as number of attempts, additional operators, alternative techniques, lifting force, external laryngeal pressure, vocal cord position, and intubation difficulty. The total score ranges from 0 to ≥5, where a score of 0 classified as easy, 1 to 5 classified as slight difficulty, and >5 as moderate to major difficulty, generally higher score means increasing difficulty
During the intubation procedure an immediate post-intubation period (within minutes after induction of general anaesthesia)
Change in Mean Arterial Pressure from baseline
Time Frame: Baseline taken during induction prior to intubation, second reading repeated at 1 minute after successful intubation
Change in Mean arterial pressure measured at 1 minute after successful intubation, expressed as percentage change from baseline value
Baseline taken during induction prior to intubation, second reading repeated at 1 minute after successful intubation
Change in Heart rate from baseline
Time Frame: Baseline measured prior to intubation, second reading repeat at 1 minute post intubation
Change in heart rate measured at 1 minute after succesful intubation, expressed as percentage change from baseline value
Baseline measured prior to intubation, second reading repeat at 1 minute post intubation

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

University of Malaya

Investigators

  • Principal Investigator: Wei Yen Yeoh, Universiti Malaya

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

December 1, 2025

Primary Completion (Actual)

March 31, 2026

Study Completion (Estimated)

May 31, 2026

Study Registration Dates

First Submitted

April 15, 2026

First Submitted That Met QC Criteria

May 4, 2026

First Posted (Actual)

May 11, 2026

Study Record Updates

Last Update Posted (Actual)

May 11, 2026

Last Update Submitted That Met QC Criteria

May 4, 2026

Last Verified

May 1, 2026

More Information

Terms related to this study

Keywords

Other Study ID Numbers

  • RSCH ID-25-06670-TVG

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

product manufactured in and exported from the U.S.

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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