This Study Evaluate the Patient Response to Jet Injection, Pain and Satisfaction Compared to Conventional Method of Local Anasthesia Especially in Maxillary Teeth

Jet Injection for Extraction of Permanent Maxillary Teeth

Pain during administration of local anesthesia remains one of the major concerns in dental practice, often leading to anxiety and treatment avoidance. Conventional syringe infiltration, while effective, is associated with discomfort during needle insertion and injection. This study aimed to evaluate the effectiveness, patient comfort, and clinical applicability of jet injection as a needle-free alternative for maxillary tooth extractions. A total of 80 adult patients were enrolled from the College of Dentistry, University of Baghdad, and Al-Amiriya Specialized Center for Dentistry between December 2024 and March 2025. Jet injection with 2% lidocaine and 1:100,000 epinephrine was delivered buccally and palatally using the Comfort-In system, and patient responses were assessed through a visual analog scale and Likert-based subjective feedback.

Study Overview

• Status: Completed
• Conditions: Jet Injection; Local Anasthesia
• Intervention / Treatment: Device: Non aspirating dental syringe; Device: The use of jet injection

• Study Type: Interventional
• Enrollment (Actual): 80
• Phase: Not Applicable

Contacts and Locations

Study Locations

• Iraq
  • Baghdad, Iraq
    • University of Baghdad College of Dentistry

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Adult; Older Adult
• Accepts Healthy Volunteers: Yes

Description

Inclusion Criteria:

• above 18 years of either gender
• had received dental anesthesia in the past with conventional syringe and needle
• required extraction on their maxillary teeth
• indicating their agreement to involving our study

Exclusion Criteria:

• adult with uncontrolled systemic conditions
• allergies to material used in this study
• patient who need surgical extraction
• intra-oral or facial swelling or presence of fistula or sinus tract
• patients who needed extraction to thier mandibular teeth patents refused to involve our study

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Other
• Allocation: Randomized
• Interventional Model: Parallel Assignment
• Masking: None (Open Label)

Number of Arms

2

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Active Comparator: Observasional group	Device: Non aspirating dental syringe; The use of non aspirating dental syringe for delivery anesthesia to upper jaw
Experimental: Study group; Use of jet injection	Device: The use of jet injection; The use of jet injectors to deliver anesthesia to upper jaw

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Visual Analogue pain Scale	use of Visual Analogue pain Scale from 1-10 to assess the pain of injection	"Perioperative/Periprocedural

Collaborators and Investigators

• Sponsor: University of Baghdad

Study record dates

Study Major Dates

• Study Start (Actual): December 15, 2024
• Primary Completion (Actual): March 1, 2025
• Study Completion (Actual): March 15, 2025

Study Registration Dates

• First Submitted: August 31, 2025
• First Submitted That Met QC Criteria: May 5, 2026
• First Posted (Actual): May 12, 2026

Study Record Updates

• Last Update Posted (Actual): May 12, 2026
• Last Update Submitted That Met QC Criteria: May 5, 2026
• Last Verified: May 1, 2026

More Information

Terms related to this study

• Other Study ID Numbers: 1040125

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: Yes
• product manufactured in and exported from the U.S.: Yes