The Effects of Physiotherapy in Migraine

June 13, 2026 updated by: Beyza Avcı, Ankara Yildirim Beyazıt University

The Effects of Physiotherapy Applications in Individuals With Migraine

The aim of this study is to investigate the effects of a physiotherapy program including cervical muscle training and transcutaneous vagus nerve stimulation on pain, functional status, quality of life, psychological status, and sleep quality in individuals with migraine.

Study Overview

Status

Not yet recruiting

Conditions

Intervention / Treatment

Study Type

Interventional

Enrollment (Estimated)

50

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Turkey (Türkiye)
      • Ankara, Turkey (Türkiye), 06560
        • Gazi Mustafa Kemal Occupational and Environmental Diseases Hospital

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult

Accepts Healthy Volunteers

No

Description

Inclusion Criteria:

  • Volunteering to participate in the study
  • Being between 18 and 55 years of age
  • Being diagnosed with migraine by a neurologist according to the International Classification of Headache Disorders 3 (ICHD-3) criteria

Exclusion Criteria:

  • Diagnosis of other primary and/or secondary headaches in addition to migraine,
  • Coexisting neurological and/or rheumatological diseases,
  • Severe psychiatric disorders (bipolar disorder, schizophrenia, psychosis, etc.),
  • Pregnancy or lactation,
  • Malignancy,
  • Known arrhythmia or presence of any implanted electronic device,
  • Presence of sensory loss in the application area,
  • Having received physiotherapy or any other treatment in the head/neck region within the last 12 months,
  • History of head/neck trauma or surgery within the last 12 months.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: None (Open Label)

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
No Intervention: Control Group
The control group will receive no intervention and will continue with their routine treatment.
Experimental: Treatment Group
In addition to routine treatments, a physiotherapy program including taVSS and cervical muscle exercises will be implemented.
Other: Physiotherapy program
A physiotherapy program including taVSS and cervical muscle exercises

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Pain Assessment
Time Frame: Baseline, 8th week (after treatment)
Individuals' pain parameters will be assessed using a pain diary.
Baseline, 8th week (after treatment)

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Assessment of Functional Status
Time Frame: Baseline, 8th week (after treatment)
The Migraine Disability Assessment Scale will be used to determine the functional status associated with migraine. This scale aims to evaluate headache-related disability and the functionality of individuals diagnosed with migraine in daily and social activities.
Baseline, 8th week (after treatment)
Quality of Life Assessment
Time Frame: Baseline, 8th week (after treatment)
The Migraine-Specific Quality of Life Scale (Version 2.1) will be used to assess quality of life.
Baseline, 8th week (after treatment)
Assessment of Psychological State
Time Frame: Baseline, 8th week (after treatment)
The Hospital Anxiety and Depression Scale will be used to assess psychological status.
Baseline, 8th week (after treatment)
Sleep Quality Assessment
Time Frame: Baseline, 8th week (after treatment)
The Single-Item Sleep Quality Scale will be used to assess sleep quality.
Baseline, 8th week (after treatment)

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Ankara Yildirim Beyazıt University

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Estimated)

August 1, 2026

Primary Completion (Estimated)

August 1, 2027

Study Completion (Estimated)

August 1, 2027

Study Registration Dates

First Submitted

June 13, 2026

First Submitted That Met QC Criteria

June 13, 2026

First Posted (Actual)

June 18, 2026

Study Record Updates

Last Update Posted (Actual)

June 18, 2026

Last Update Submitted That Met QC Criteria

June 13, 2026

Last Verified

June 1, 2026

More Information

Terms related to this study

Additional Relevant MeSH Terms

Other Study ID Numbers

  • AYBU-2026-05

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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