- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT07671144
Visual Perception, Binocular Rivalry, and Fatigue-Related Individual Differences in Colour and Illumination Judgement
Characterising Individual Differences in Colour Perception and Binocular Rivalry and Their Associations With Chronotype, Sex, and Sleep
Study Overview
Status
Conditions
Intervention / Treatment
Detailed Description
Colour perception and binocular rivalry both show variability across individuals. However, the extent to which these individual differences are stable and whether they are associated with personal or physiological factors remains unclear. This study will use behavioural visual perception tasks to measure individual differences in colour perception and binocular rivalry. Participants will complete a colour perception task and a binocular rivalry task, along with questionnaire measures related to chronotype, sleep, fatigue, and demographic characteristics including sex.
The primary aim is to determine whether measurable individual differences are present in colour perception and binocular rivalry performance. The secondary aim is to examine whether these differences are associated with chronotype, sex, sleep-related variables, and subjective fatigue. The study is observational and does not involve a clinical intervention, drug, biologic product, or medical device.
Study Type
Enrollment (Estimated)
Contacts and Locations
Study Contact
- Name: Cehao Yu, PhD
- Phone Number: +852 3400 3012
- Email: cehao.yu@polyu.edu.hk
Study Contact Backup
- Name: Junkai Che, Master
- Phone Number: +852 9783 8643
- Email: junkai.che@connect.polyu.hk
Study Locations
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-
Kowloon
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Hung Hom, Kowloon, Hong Kong
- The Hong Kong Polytechnic University, Department of Applied Social Sciences
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Contact:
- Cehao Yu, PhD
- Phone Number: +852 3400 3012
- Email: cehao.yu@polyu.edu.hk
-
Contact:
- Junkai Che, Master
- Phone Number: +852 9783 8643
- Email: junkai.che@connect.polyu.hk
-
-
Participation Criteria
Eligibility Criteria
Ages Eligible for Study
- Adult
Accepts Healthy Volunteers
Sampling Method
Study Population
Description
Inclusion Criteria:
- Adults aged 18 years or older.
- Normal or corrected-to-normal visual acuity.
- Normal or corrected-to-normal binocular vision.
- Normal colour vision, or no self-reported colour vision deficiency.
- Able to understand the study instructions and provide informed consent.
- Able to complete computer-based visual perception tasks and self-report questionnaires.
Exclusion Criteria:
- Self-reported colour vision deficiency.
- Uncorrected visual impairment or eye conditions that may interfere with visual perception tasks.
- Strabismus, amblyopia, or other binocular vision problems that may interfere with binocular rivalry testing.
- History of neurological disorders, photosensitive epilepsy, or severe sensitivity to flickering visual stimuli.
- Current condition or medication that, in the investigator's judgment, may substantially affect visual perception, attention, or task performance.
- Inability to complete the task procedures or provide valid responses.
Study Plan
How is the study designed?
Design Details
Cohorts and Interventions
Group / Cohort |
Intervention / Treatment |
|---|---|
|
Healthy Adult Participants
Healthy adult volunteers aged 18 to 25 years with normal or corrected-to-normal visual acuity and normal colour vision, recruited from the university and surrounding community.
In a single laboratory session, participants complete computer-based colour perception and binocular rivalry tasks and self-report questionnaires on chronotype, sleep, fatigue, and demographic characteristics.
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Participants will complete computer-based visual perception tasks, including a colour perception task and a binocular rivalry task.
These tasks are used to measure individual differences in perceptual responses and are not intended as a clinical intervention.
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What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
|---|---|---|
|
Mean colour-adjustment values on the colour perception task
Time Frame: Day 1 (single laboratory session)
|
Colour perception will be measured using a computer-based colour adjustment task.
Participants will adjust the appearance of a target object or stimulus, and outcome variables will include adjustment values in colour space, such as chromaticity, hue, saturation, or luminance-related measures, depending on the final task implementation.
These measures will be used to characterise individual differences in colour perception.
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Day 1 (single laboratory session)
|
|
Mean perceptual dominance duration during binocular rivalry
Time Frame: Day 1 (single laboratory session)
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Binocular rivalry is measured with a computer-based dichoptic task in which a different image is presented to each eye.
Perceptual dominance duration is the mean length of time, in seconds, that one stimulus remains exclusively visible before perception switches to the other.
Longer mean durations indicate more stable, slower-switching rivalry.
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Day 1 (single laboratory session)
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Mean alternation rate during binocular rivalry
Time Frame: Day 1 (single laboratory session)
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Binocular rivalry is measured with the same computer-based dichoptic task.
Alternation rate is the mean number of perceptual switches between the two stimuli per minute of viewing.
Higher alternation rates indicate faster perceptual switching between the two eyes' images.
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Day 1 (single laboratory session)
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Secondary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
|---|---|---|
|
Morningness-Eveningness Questionnaire (MEQ) score
Time Frame: Day 1 (single laboratory session)
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Chronotype assessed using the Morningness-Eveningness Questionnaire (MEQ).
Total scores range from 16 to 86; higher scores indicate greater morningness (a stronger morning-type preference) and lower scores indicate greater eveningness.
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Day 1 (single laboratory session)
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Pittsburgh Sleep Quality Index (PSQI) global score
Time Frame: Administered once, within 7 days before or at the single laboratory session (Day 1); the PSQI assesses sleep over the preceding 1 month.
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Sleep quality assessed using the Pittsburgh Sleep Quality Index (PSQI).
The global score is the sum of seven component scores and ranges from 0 to 21; higher scores indicate worse sleep quality (a global score above 5 indicates poor sleep quality).
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Administered once, within 7 days before or at the single laboratory session (Day 1); the PSQI assesses sleep over the preceding 1 month.
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Karolinska Sleepiness Scale (KSS) score
Time Frame: Day 1: assessed immediately before and immediately after the visual perception tasks, which are completed within a single session lasting up to approximately 1 hour.
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Subjective sleepiness/fatigue assessed using the Karolinska Sleepiness Scale (KSS), a single-item 9-point scale.
Scores range from 1 to 9; higher scores indicate greater sleepiness.
The pre-task to post-task change in KSS score may also be reported.
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Day 1: assessed immediately before and immediately after the visual perception tasks, which are completed within a single session lasting up to approximately 1 hour.
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Collaborators and Investigators
Investigators
- Principal Investigator: Cehao Yu, PhD, The Hong Kong Polytechnic University
Publications and helpful links
General Publications
- Yang E, Blake R, McDonald JE 2nd. A new interocular suppression technique for measuring sensory eye dominance. Invest Ophthalmol Vis Sci. 2010 Jan;51(1):588-93. doi: 10.1167/iovs.08-3076. Epub 2009 Jul 23.
- Webster MA, Miyahara E, Malkoc G, Raker VE. Variations in normal color vision. II. Unique hues. J Opt Soc Am A Opt Image Sci Vis. 2000 Sep;17(9):1545-55. doi: 10.1364/josaa.17.001545.
- Foster DH. Color constancy. Vision Res. 2011 Apr 13;51(7):674-700. doi: 10.1016/j.visres.2010.09.006. Epub 2010 Sep 16.
- Wallisch P. Illumination assumptions account for individual differences in the perceptual interpretation of a profoundly ambiguous stimulus in the color domain: "The dress". J Vis. 2017 Apr 1;17(4):5. doi: 10.1167/17.4.5.
- Gegenfurtner KR, Bloj M, Toscani M. The many colours of 'the dress'. Curr Biol. 2015 Jun 29;25(13):R543-4. doi: 10.1016/j.cub.2015.04.043. Epub 2015 May 14.
- Lafer-Sousa R, Hermann KL, Conway BR. Striking individual differences in color perception uncovered by 'the dress' photograph. Curr Biol. 2015 Jun 29;25(13):R545-6. doi: 10.1016/j.cub.2015.04.053. Epub 2015 May 14.
- Toscani M, Gegenfurtner KR, Doerschner K. Differences in illumination estimation in #thedress. J Vis. 2017 Jan 1;17(1):22. doi: 10.1167/17.1.22.
Study record dates
Study Major Dates
Study Start (Estimated)
Primary Completion (Estimated)
Study Completion (Estimated)
Study Registration Dates
First Submitted
First Submitted That Met QC Criteria
First Posted (Actual)
Study Record Updates
Last Update Posted (Actual)
Last Update Submitted That Met QC Criteria
Last Verified
More Information
Terms related to this study
Keywords
Other Study ID Numbers
- HSEARS20260621001 (Other Identifier: The Hong Kong Polytechnic University)
Plan for Individual participant data (IPD)
Plan to Share Individual Participant Data (IPD)?
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
Studies a U.S. FDA-regulated device product
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