Effect of Implementing Cough Augmentation Techniques on Weaning Outcomes Among Critically Ill Patients

July 19, 2026 updated by: Heba.Attia@nur.dmu.edu.eg
The study aims to determine the effect of implementing cough augmentation techniques on weaning outcomes among critically ill patients

Study Overview

Status

Recruiting

Conditions

Intervention / Treatment

Detailed Description

Cough augmentation techniques are important interventions for critically ill patients who have impaired cough strength due to mechanical ventilation, neuromuscular weakness, sedation, or respiratory muscle dysfunction. These techniques, which include manual assisted cough, lung volume recruitment, and mechanical insufflation-exsufflation, enhance expiratory airflow and improve the clearance of airway secretions

Study Type

Interventional

Enrollment (Estimated)

88

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

Study Contact Backup

Study Locations

  • Egypt
      • Damanhūr, Egypt
        • Recruiting
        • Faculty of Nursing, Damanhur University
        • Contact:
        • Contact:
        • Principal Investigator:
          • heba attia, lecturer

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult
  • Older Adult

Accepts Healthy Volunteers

No

Description

Inclusion Criteria:

  • adult intubated patients
  • both sex

Exclusion Criteria:

  • patient with facial trauma
  • patient with tracheostomy tube

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Supportive Care
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: Single

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: Interventional group
the experimental group receive the cough augmentation techniques
Other: cough augmentation techniques
the lung volume recruitment maneuver via MV was applied with assistant of the attended physician as follows: Use pressure-controlled ventilation and increase end-inspiratory volume (30 or 40 cm H2O for 30 to 40 seconds unless contraindicated) or inspiratory hold for 30 to 40 seconds to promote cough effectiveness. The patient serially inhales a volume of gas without exhalation until maximum insufflation capacity via the ventilator to facilitate breath-holding (if not contraindicated).
No Intervention: conventional group
receive the routine care in the unit

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
weaning success
Time Frame: within 7 days
measured through successful extubating
within 7 days

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Heba.Attia@nur.dmu.edu.eg

Investigators

  • Principal Investigator: sahar youness, professor, professor of critical care and emergency nursing

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Helpful Links

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Estimated)

July 8, 2026

Primary Completion (Estimated)

October 8, 2026

Study Completion (Estimated)

November 10, 2026

Study Registration Dates

First Submitted

July 19, 2026

First Submitted That Met QC Criteria

July 19, 2026

First Posted (Actual)

July 23, 2026

Study Record Updates

Last Update Posted (Actual)

July 23, 2026

Last Update Submitted That Met QC Criteria

July 19, 2026

Last Verified

July 1, 2026

More Information

Terms related to this study

Keywords

Other Study ID Numbers

  • 55-d

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

YES

IPD Plan Description

55-d

IPD Sharing Time Frame

at January 2026, and will be available for 5 years

IPD Sharing Access Criteria

any researcher will be able to access the IPD foe study protocol through contacting us

IPD Sharing Supporting Information Type

  • STUDY_PROTOCOL

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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