Sales and pricing decisions for HIV self-test kits among local drug shops in Tanzania: a prospective cohort study

Calvin Chiu, Lauren A Hunter, Sandra I McCoy, Rashid Mfaume, Prosper Njau, Jenny X Liu, Calvin Chiu, Lauren A Hunter, Sandra I McCoy, Rashid Mfaume, Prosper Njau, Jenny X Liu

Abstract

Background: Public health initiatives must look for ways to cost-effectively scale critical interventions to achieve high coverage. Private sector distribution channels, can potentially distribute preventive healthcare products to hard-to-reach populations, decongest public healthcare systems, and increase the sustainability of programs by getting customers to share costs. However, little is known about how sellers set prices for new products. By introducing a new product, HIV self-test kits, to local drug shops, we observed whether shops experimented with pricing, charged different buyers different prices, and whether prices converged within the local market over our study period.

Methods: From August to December 2019, we provided free HIV self-test kits, a new product, to 26 drug shops in Shinyanga, Tanzania to sell to the local community. We measured sales volume, price, customer age and sex using shop records. Using a multiple linear regression model, we conducted F-tests to determine whether shop, age, sex, and time (week) respectively were associated with price. We measured willingness-to-pay to restock test kits at the end of the study.

Results: 514 test kits were sold over 18 weeks; 69% of buyers were male, 40% were aged 25-34 and 32% aged 35-44. Purchase prices ranged from 1000 to 6000 Tsh (median 3000 Tsh; ~$1.30 USD). Within shops, prices were 11.3% higher for 25-34 and 12.7% higher for 45+ year olds relative to 15-19-year olds (p = 0.029) and 13.5% lower for men (p = 0.023) on average. Although prices varied between shops, prices varied little within shops over time, and did not converge over the study period or cluster geospatially. Mean maximum willingness-to-pay to restock was 2000 Tsh per kit.

Conclusions: Shopkeepers charged buyers different prices depending on buyers' age and sex. There was limited variation in prices within shops over time and low demand among shopkeepers to restock at the end of the study. Given the subsidized global wholesale price ($2 USD or ~ 4600 Tsh), further demand creation and/or cost-reduction is required before HIV self-test kits can become commercially viable in drug shops in this setting. Careful consideration is needed to align the motivations of retailers with public health priorities while meeting their private for-profit needs.

Keywords: Drug shops; HIV self-testing; Pricing; Private sector distribution.

Conflict of interest statement

The authors declare that they have no competing interests.

Figures

Fig. 1
Fig. 1
Distribution of HIV self-test kit sales price within drug shops over time. Each graph represents a shop in our study (n = 23). Each graph plots the sales price (Tsh) of each test kit sold over the study period (August to December 2019). Blank spaces indicate no test kits sold. $1 USD approx. 2300 Tsh
Fig. 2
Fig. 2
Accuracy of recall and beliefs about HIV self-test kit sales and pricing. Box plot of shop owners’ beliefs about other shops’ sales volume and pricing of HIV self-test kits and recall of their own sales volume and pricing in the last week and month respectively, measured at the end of the study period (n = 25)
Fig. 3
Fig. 3
Willingness to restock HIV self-test kits at given price levels per kit (Tsh). Note: $1 USD approx. 2300 Tsh. The subsidized global negotiated wholesale price is ~ 4600 Tsh per HIV self-test kit. Only 15/25 (60%) of shops were willing to restock at 2000 Tsh per test kit (the mean maximum willingness-to-pay to restock)

References

    1. Awor P, Wamani H, Bwire G, Jagoe G, Peterson S. Private sector drug shops in integrated community case management of malaria, pneumonia, and diarrhea in children in Uganda. Am J Trop Med Hyg. 2012;87(SUPPL.5):92–96. doi: 10.4269/ajtmh.2012.11-0791.
    1. Awor P, Wamani H, Tylleskar T, Jagoe G, Peterson S. Increased access to care and appropriateness of treatment at private sector drug shops with integrated management of malaria, pneumonia and diarrhoea: a quasi-experimental study in Uganda. PLoS One. 2014;9(12):1–15. doi: 10.1371/journal.pone.0115440.
    1. Goodman C, Brieger W, Unwin A, Mills A, Greer G. Medicine sellers and malaria treatment in sub-Saharan Africa: what do they do and how can their practice be improved? Am J Trop Med. 2010;77(0):203–218.
    1. Treleaven E, Liu J, Prach LM, et al. Management of paediatric illnesses by patent and proprietary medicine vendors in Nigeria. Malar J. 2015;14:232. 10.1186/s12936-015-0747-7.
    1. Liu J, Prach LM, Treleaven E, Hansen M, Anyanti J, Jagha T, Seaman V, Ajumobi O, Isiguzo C. The role of drug vendors in improving basic health-care services in Nigeria. Bull World Health Organ. 2016;94(4):267–275. doi: 10.2471/BLT.15.154666.
    1. Beyeler N, Liu J, Sieverding M. A systematic review of the role of proprietary and patent medicine vendors in healthcare provision in Nigeria. PLoS One. 2015;10(1):1–21. doi: 10.1371/journal.pone.0117165.
    1. Bloom G, Standing H, Lucas H, Bhuiya A, Oladepo O, Peters DH. Making health markets work better for poor people: the case of informal providers. Health Plicy Plan. 2011;26(1):45–52. doi: 10.1093/heapol/czr025.
    1. Kagashe GAB, Minzi O, Matowe L. An assessment of dispensing practices in private pharmacies in Dar-es-salaam, Tanzania. 2011;30–35.
    1. Dusabe J, Mchome Z, Nnko S, Changalucha J, Obasi A. “There are bugs in condoms”: Tanzanian close-to-community providers’ ability to offer effective adolescent reproductive health services. J Fam Plann Reprod Health Care. 2015;41(1):e2. doi: 10.1136/jfprhc-2014-100915.
    1. Rutta E, Liana J, Embrey M, Johnson K, Kimatta S, Valimba R, et al. Accrediting retail drug shops to strengthen Tanzania ’ s public health system : an ADDO case study. J Pharm Policy Pract [Internet]. 2015;8: 1–15. Available from:
    1. Akol A, Chin-Quee D, Wamala-Mucheri P, Namwebya JH, Mercer SJ, Stanback J. Getting closer to people: family planning provision by drug shops in Uganda. Glob Heal Sci Pract [Internet] 2014;2(4):472–481. doi: 10.9745/GHSP-D-14-00085.
    1. Corroon M, Kebede E, Spektor G, Speizer I. Key Role of Drug Shops and Pharmacies for Family Planning in Urban Nigeria and Kenya. Glob Heal Sci Pract [Internet] 2016;4(4):594 LP–594609. doi: 10.9745/GHSP-D-16-00197.
    1. Maughan-Brown B, Kuo C, Galárraga O, Smith P, Lurie MN, Bekker L, et al. Stumbling blocks at the clinic: experiences of seeking HIV treatment and Care in South Africa. AIDS Behav [Internet] 2018;22(3):765–773. Available from:
    1. Sanga ES, Mukumbang FC, Mushi AK, Lerebo W, Zarowsky C. Understanding factors influencing linkage to HIV care in a rural setting, Mbeya, Tanzania: qualitative findings of a mixed methods study. BMC Public Health. 2019;19(1):1–15.
    1. Thirumurthy H, Masters SH, Agot K. Willingness to pay for HIV self-tests among women in Kenya: implications for subsidy and pricing policies. J Acquir Immune Defic Syndr. 2018;78(2):e8–11. doi: 10.1097/QAI.0000000000001659.
    1. Masters SH, Agot K, Obonyo B, Napierala Mavedzenge S, Maman S, Thirumurthy H. Promoting partner testing and couples testing through secondary distribution of HIV self-tests: a randomized clinical trial. PLoS Med. 2016;13(11):1–15. doi: 10.1371/journal.pmed.1002166.
    1. Thirumurthy H, Masters SH, Mavedzenge SN, Maman S, Omanga E, Agot K. Promoting male partner HIV testing and safer sexual decision making through secondary distribution of self-tests by HIV-negative female sex workers and women receiving antenatal and post-partum care in Kenya: a cohort study. Lancet HIV [Internet] 2016;3(6):e266–e274. doi: 10.1016/S2352-3018(16)00041-2.
    1. Mugo PM, Micheni M, Shangala J, Hussein MH, Graham SM, De R, Wit TF, et al. Uptake and acceptability of oral HIV self-testing among community pharmacy clients in Kenya: a feasibility study. PLoS One. 2017;12(1):1–15. doi: 10.1371/journal.pone.0170868.
    1. Chang W, Matambanadzo P, Takaruza A, Hatzold K, Cowan FM, Sibanda E, Thirumurthy H. Effect of prices, distribution strategies, and marketing on demand for HIV self-testing in Zimbabwe: a randomized clinical trial. JAMA Netw Open. 2019;2(8):e199818. doi: 10.1001/jamanetworkopen.2019.9818.
    1. Aylward P, Essendi H, Little K, Wilson N. Demand for self-tests: Evidence from a Becker–DeGroot–Marschak mechanism field experiment. Heal Econ (United Kingdom) 2020;29(4):1–19.
    1. Dupas P, Miguel E. Chapter 1 - Impacts and Determinants of Health Levels in Low-Income Countries. In: Banerjee AV, Duflo E, editors. Handbook of Economic Field Experiments, vol. 2. North-Holland: 2017. p. 3-93. ISSN 2214-658X, ISBN 9780444640116. 10.1016/bs.hefe.2016.09.003. .
    1. Hunter LA, Liu JX, Rao A, Napierala S, Kalinjila A, Mnyippembe A, et al. Drug shops are an effective strategy to reach adolescent girls and young women with HIV self-testing and contraception: A randomized trial in Tanzania. In: AIDS 2020 – 23rd International AIDS Conference. 2020.
    1. Anderson S, Harrison GW, Lau MI, Rutstrom EE. Valuation using multiple price list formats. Appl Econ. 2007;39(6):675–682. doi: 10.1080/00036840500462046.
    1. Wafula FN, Goodman CA. Are interventions for improving the quality of services provided by specialized drug shops effective in sub-Saharan Africa? A systematic review of the literature. Int J Qual Heal Care. 2010;22(4):316–323. doi: 10.1093/intqhc/mzq022.
    1. Wafula FN, Miriti EM, Goodman CA. Examining characteristics, knowledge and regulatory practices of specialized drug shops in Sub-Saharan Africa: A systematic review of the literature. BMC Health Serv Res. 2012;12(1):223. doi: 10.1186/1472-6963-12-223.
    1. Cohen J, Dupas P, Schaner S. Price subsidies, diagnostic tests, and targeting of malaria treatment: evidence from a randomized controlled trial. Am Econ Rev. 2015;105(2):609–645. doi: 10.1257/aer.20130267.
    1. Aung T, White C, Montagu D, McFarland W, Hlaing T, Khin HSS, et al. Improving uptake and use of malaria rapid diagnostic tests in the context of artemisinin drug resistance containment in eastern Myanmar: an evaluation of incentive schemes among informal private healthcare providers. Malar J. 2015;14(1):1–9. doi: 10.1186/1475-2875-14-1.
    1. OraSure Technologies I. Oraquick HIV self-test [Internet]. 2013 [cited 2020 Jun 19]. Available from:
    1. Sieverding M, Liu J, Beyeler N. Social support in the practices of informal providers: the case of patent and proprietary medicine vendors in Nigeria. Soc Sci Med [Internet] 2015;143:17–25. Available from:
    1. Fischer G, Karlan D, McConnell M, Raffler P. Short-term subsidies and seller type: A health products experiment in Uganda. J Dev Econ [Internet] 2019;137:110–124. doi: 10.1016/j.jdeveco.2018.07.013.

Source: PubMed

3
Subscribe