Factors Associated With Discharge Home Among Medical ICU Patients in an Early Mobilization Program

Roger Y Kim, Terrence E Murphy, Margaret Doyle, Catherine Pulaski, Maura Singh, Sui Tsang, Dawn Wicker, Margaret A Pisani, Geoffrey R Connors, Lauren E Ferrante, Roger Y Kim, Terrence E Murphy, Margaret Doyle, Catherine Pulaski, Maura Singh, Sui Tsang, Dawn Wicker, Margaret A Pisani, Geoffrey R Connors, Lauren E Ferrante

Abstract

Objectives: One goal of early mobilization programs is to facilitate discharge home after an ICU hospitalization, but little is known about which factors are associated with this outcome. Our objective was to evaluate factors associated with discharge home among medical ICU patients in an early mobilization program who were admitted to the hospital from home.

Design: Retrospective cohort study of medical ICU patients in an early mobilization program.

Setting: Tertiary care center medical ICU.

Patients: Medical ICU patients receiving early mobilization who were community-dwelling prior to admission.

Interventions: None.

Measurements and main results: A comprehensive set of baseline, ICU-related, and mobilization-related factors were tested for their association with discharge home using multivariable logistic regression. Among the analytic cohort (n = 183), the mean age was 61.9 years (sd 16.67 yr) and the mean Acute Physiology and Chronic Health Evaluation II score was 23.5 (sd 7.11). Overall, 65.0% of patients were discharged home after their critical illness. In multivariable analysis, each incremental increase in the maximum level of mobility achieved (range, 1-6) during the medical ICU stay was associated with nearly a 50% greater odds of discharge home (odds ratio, 1.46; 95% CI, 1.13-1.88), whereas increased age (odds ratio, 0.95; 95% CI, 0.93-0.98) and greater hospital length of stay (odds ratio, 0.94; 95% CI, 0.90-0.99) were associated with decreased odds of discharge home. Prehospital ambulatory status was not associated with discharge home.

Conclusions: Among medical ICU patients who resided at home prior to their ICU admission, the maximum level of mobility achieved in the medical ICU was the factor most strongly associated with discharge back home. Identification of this factor upon ICU-to-ward transfer may help target mobilization plans on the ward to facilitate a goal of discharge home.

Keywords: critical care; critical care outcomes; early mobilization; patient discharge; physical and rehabilitation medicine.

Copyright © 2019 The Authors. Published by Wolters Kluwer Health, Inc. on behalf of the Society of Critical Care Medicine.

Figures

Figure 1.
Figure 1.
Assembly of the analytic sample from the parent cohorts. All medical ICU (MICU) admissions during initial implementation of an early mobilization program (March 26, 2015, to June 30, 2015) and 1 yr later (March 26, 2016, to June 30, 2016) were identified. After confirming there were no statistically significant differences between these two patient cohorts, a combined cohort was established. Patients with goals of comfort measures only, discharge to hospice, excessively long length of stay (LOS) (MICU > 21 d or hospital > 45 d), or history of limb amputation were excluded. The first hospitalization per patient per year was selected, and for patients with multiple ICU admissions within a single hospital stay, data were included from all MICU stays. We then selected patients admitted to the hospital from home. The analytic sample included 183 MICU admissions. SNF = skilled nursing facility.
Figure 2.
Figure 2.
Percent of discharges home by level of maximum mobility in the medical ICU (MICU). The maximum levels of mobility in the MICU are as follows: 1—therapeutic (in-bed) exercises, 2—bed mobility (supine-to-sit), 3—transfer training (sit-to-stand/bed-to-chair), 4—gait training (

References

    1. Vincent JL, Singer M. Critical care: Advances and future perspectives. Lancet 2010; 376:1354–1361
    1. Polverino E, Nava S, Ferrer M, et al. Patients’ characterization, hospital course and clinical outcomes in five Italian respiratory intensive care units. Intensive Care Med 2010; 36:137–142
    1. Zimmerman JE, Kramer AA, Knaus WA, et al. Changes in hospital mortality for United States intensive care unit admissions from 1988 to 2012. Crit Care 2013; 17:R81.
    1. Schweickert WD, Pohlman MC, Pohlman AS, et al. Early physical and occupational therapy in mechanically ventilated, critically ill patients: A randomised controlled trial. Lancet 2009; 373:1874–1882
    1. Schaller SJ, Anstey M, Blobner M, et al. ; International Early SOMS-guided Mobilization Research Initiative: Early, goal-directed mobilisation in the surgical intensive care unit: A randomised controlled trial. Lancet 2016; 388:1377–1388
    1. Burtin C, Clerckx B, Robbeets C, et al. Early exercise in critically ill patients enhances short-term functional recovery. Crit Care Med 2009; 37:2499–2505
    1. Tipping CJ, Harrold M, Holland A, et al. The effects of active mobilisation and rehabilitation in ICU on mortality and function: A systematic review. Intensive Care Med 2017; 43:171–183
    1. Pohlman MC, Schweickert WD, Pohlman AS, et al. Feasibility of physical and occupational therapy beginning from initiation of mechanical ventilation. Crit Care Med 2010; 38:2089–2094
    1. Morris PE, Goad A, Thompson C, et al. Early intensive care unit mobility therapy in the treatment of acute respiratory failure. Crit Care Med 2008; 36:2238–2243
    1. Hodgson CL, Stiller K, Needham DM, et al. Expert consensus and recommendations on safety criteria for active mobilization of mechanically ventilated critically ill adults. Crit Care 2014; 18:658.
    1. Wells CL, Forrester J, Vogel J, et al. Safety and feasibility of early physical therapy for patients on extracorporeal membrane oxygenator: University of Maryland Medical Center experience. Crit Care Med 2018; 46:53–59
    1. Kayambu G, Boots R, Paratz J, et al. Physical therapy for the critically ill in the ICU: A systematic review and meta-analysis. Crit Care Med 2013; 41:1543–1554
    1. Castro-Avila AC, Serón P, Fan E, et al. Effect of early rehabilitation during intensive care unit stay on functional status: Systematic review and meta-analysis. PLoS One 2015; 10:e0130722.
    1. Adler J, Malone D. Early mobilization in the intensive care unit: A systematic review. Cardiopulm Phys Ther J 2012; 23:5–13
    1. Morris PE, Berry MJ, Files DC, et al. Standardized rehabilitation and hospital length of stay among patients with acute respiratory failure: A randomized clinical trial. JAMA 2016; 315:2694–2702
    1. Ota H, Kawai H, Sato M, et al. Effect of early mobilization on discharge disposition of mechanically ventilated patients. J Phys Ther Sci 2015; 27:859–864
    1. Hodgson CL, Bailey M, Bellomo R, et al. ; Trial of Early Activity and Mobilization Study Investigators: A binational multicenter pilot feasibility randomized controlled trial of early goal-directed mobilization in the ICU. Crit Care Med 2016; 44:1145–1152
    1. Denehy L, Skinner EH, Edbrooke L, et al. Exercise rehabilitation for patients with critical illness: A randomized controlled trial with 12 months of follow-up. Crit Care 2013; 17:R156.
    1. Moss M, Nordon-Craft A, Malone D, et al. A randomized trial of an intensive physical therapy program for patients with acute respiratory failure. Am J Respir Crit Care Med 2016; 193:1101–1110
    1. Owens JM, Callaghan JJ, Duchman KR, et al. Short-term morbidity and readmissions increase with skilled nursing facility discharge after total joint arthroplasty in a medicare-eligible and skilled nursing facility-eligible patient cohort. J Arthroplasty 2018; 33:1343–1347
    1. Rady MY, Johnson DJ. Hospital discharge to care facility: A patient-centered outcome for the evaluation of intensive care for octogenarians. Chest 2004; 126:1583–1591
    1. Allen LA, Hernandez AF, Peterson ED, et al. Discharge to a skilled nursing facility and subsequent clinical outcomes among older patients hospitalized for heart failure. Circ Heart Fail 2011; 4:293–300
    1. Arrighi-Allisan AE, Neifert SN, Gal JS, et al. Discharge destination as a predictor of postoperative outcomes and readmission following posterior lumbar fusion. World Neurosurg 2019; 122:e139–e146
    1. Werner RM, Coe NB, Qi M, et al. Patient outcomes after hospital discharge to home with home health care vs to a skilled nursing facility. JAMA Intern Med 2019; 179:617–623
    1. Hoyer EH, Young DL, Friedman LA, et al. Routine inpatient mobility assessment and hospital discharge planning. JAMA Intern Med 2019; 179:118–120
    1. Mulkey M, Bena JF, Albert NM, et al. Clinical outcomes of patient mobility in a neuroscience intensive care unit. J Neurosci Nurs 2014; 46:153–161; quiz E1–E2
    1. Probasco JC, Lavezza A, Cassell A, et al. Choosing wisely together: Physical and occupational therapy consultation for acute neurology inpatients. Neurohospitalist 2018; 8:53–59
    1. Salisbury LG, Merriweather JL, Walsh TS, et al. The development and feasibility of a ward-based physiotherapy and nutritional rehabilitation package for people experiencing critical illness. Clin Rehabil 2010; 24:489–500
    1. Harris PA, Taylor R, Thielke R, et al. Research electronic data capture (REDCap)–a metadata-driven methodology and workflow process for providing translational research informatics support. J Biomed Inform 2009; 42:377–381
    1. Hopkins RO, Miller RR, III, Rodriguez L, et al. Physical therapy on the wards after early physical activity and mobility in the intensive care unit. Phys Ther 2012; 92:1518–1523
    1. Burke RE, Jones J, Lawrence E, et al. Evaluating the quality of patient decision-making regarding post-acute care. J Gen Intern Med 2018; 33:678–684
    1. Kolko J.“Normal America” Is Not a Small Town of White People. 2016. Available at: . Accessed May 28, 2019.

Source: PubMed

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