Is the Outcome of Pulmonary Resections due to Non-Small Cell Lung Cancer in Octogenarian Patients Worse?

Ali Cevat Kutluk, Hasan Akin, Altan Ceritoglu, Celalettin Ibrahim Kocaturk, Salih Bilen, Yasar Sonmezoglu, Kemal Karapinar, Ali Cevat Kutluk, Hasan Akin, Altan Ceritoglu, Celalettin Ibrahim Kocaturk, Salih Bilen, Yasar Sonmezoglu, Kemal Karapinar

Abstract

Purpose: Lung cancer is one of the major sources of mortality in the elderly. This study was undertaken to assess the early and long-term results of surgical resection in patients older than 70 years of age by comparing the results of patients aged 70-79 years (group 1) with patients older than 80 years of age (group 2).

Methods: Data on patient age, gender, spirometry values, side, size, histology and stage of the tumor, surgical procedures, postoperative complications, Charlson comorbidity scores (CCS), and survival were collected.

Results: After 1-2 propensity score matching group 1 (70-79 years) included 84 and group 2 (age over 80) 42 cases. The multivariate analysis showed that CCS was the only significant factor affecting the development of complications (p = 0.003). The overall median and 5-year survival of all patients were 55 months and 42.5%, respectively. Although the survival of the elderly group 2 was higher than the first group, the difference did not reach significance (50 vs. 49 months, respectively).

Conclusion: The outcomes of surgery in terms of morbidity and mortality rates do not differ between the two age groups. The safety of pulmonary resections in the elderly group is comparable to patients under 70 years if the comorbidities are appropriately controlled. In addition, surgery provides satisfactory survival rates in both age groups.

Keywords: non-small cell lung cancer; octogenarian; surgery.

Figures

Fig. 1. Flow chart showing the path…
Fig. 1. Flow chart showing the path of the patients in the study. NSCLC: non-small cell lung cancer
Fig. 2. The survival analysis of the…
Fig. 2. The survival analysis of the two groups.

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