Benefits of pulmonary rehabilitation in idiopathic pulmonary fibrosis
Jeffrey J Swigris, Diane L Fairclough, Marianne Morrison, Barry Make, Elizabeth Kozora, Kevin K Brown, Frederick S Wamboldt, Jeffrey J Swigris, Diane L Fairclough, Marianne Morrison, Barry Make, Elizabeth Kozora, Kevin K Brown, Frederick S Wamboldt
Abstract
Background: Information on the benefits of pulmonary rehabilitation (PR) in patients with idiopathic pulmonary fibrosis (IPF) is growing, but PR's effects on certain important outcomes is lacking.
Methods: We conducted a pilot study of PR in IPF and analyzed changes in functional capacity, fatigue, anxiety, depression, sleep, and health status from baseline to after completion of a standard, 6-week PR program.
Results: Six-min walk distance improved a mean ± standard error 202 ± 135 feet (P = .01) from baseline. Fatigue Severity Scale score also improved significantly, declining an average 1.5 ± 0.5 points from baseline. There were trends toward improvement in anxiety, depression, and health status.
Conclusions: PR improves functional capacity and fatigue in patients with IPF. (Clinical Trials.gov registration NCT00692796.)
Conflict of interest statement
The authors have disclosed no conflicts of interest.
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Source: PubMed