ENT manifestation in COVID-19 patients

Mohammad Waheed El-Anwar, Saad Elzayat, Yasser Ahmed Fouad, Mohammad Waheed El-Anwar, Saad Elzayat, Yasser Ahmed Fouad

Abstract

Objective: to detect, analyze and discuss the different ear nose throat (ENT) manifestations those were reported in COVID19 positive patients in the reviewed and published literatures.

Methods: We performed a search in the PubMed databases, Web of Science, LILACS, MEDLINE, SciELO, and Cochrane Library using the keywords; COVID-19, Novel coronavirus, corona, 2019-nCoV, SARS-CoV-2, ENT, ear, nose, throat, otorhinolaryngology, ORL, pharynx, ORL, smell, larynx, different ENT related symptoms. We reviewed published and peer reviewed studies that reported the ENT manifestations in COVID-19 laboratory-confirmed positive patients.

Results: within the included 1773 COVID-19 laboratory-confirmed positive patients, the most common ENT manifestations of COVID-19 were sore throat (11.3%) and headache (10.7%). While the other reported ENT manifestations were pharyngeal erythema (5.3%), nasal congestion (4.1%), runny nose or rhinorrhea (2.1%), upper respiratory tract infection (URTI) (1.9%), and tonsil enlargement (1.3%).

Conclusion: ENT manifestations for COVID-19 are not common as fever and cough. But, a universal questionnaire using well-defined COVID-19 manifestations is needed to make the COVID-19 data precisely defined, complete and homogenous.

Keywords: COVID-19; ENT; corona virus; nasal manifestation; nose; otorhinolaryngology; pharynx.

Conflict of interest statement

Declaration of Competing Interest The authors declare no conflict of interest and do not have any potential financial conflict of interest related to or could influence this work.

Copyright © 2020. Published by Elsevier B.V.

Figures

Fig. 1
Fig. 1
chart shows incidence of ENT manifestations in COVID-19 patients.
Fig. 2
Fig. 2
chart shows incidence of non-ENT manifestations in COVID-19 patients.
Fig. 3
Fig. 3
chart shows incidence of ENT and non ENT manifestations in COVID-19 patients.

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