Metabolic syndrome prevalence according to ATP III and IDF criteria and related factors in Turkish adults

Kursat Gundogan, Fahri Bayram, Vedia Gedik, Ahmet Kaya, Ahmet Karaman, Ozgür Demir, Tevfik Sabuncu, Derya Kocer, Ramazan Coskun, Kursat Gundogan, Fahri Bayram, Vedia Gedik, Ahmet Kaya, Ahmet Karaman, Ozgür Demir, Tevfik Sabuncu, Derya Kocer, Ramazan Coskun

Abstract

Introduction: The aim of this study is to investigate the prevalence of metabolic syndrome (MS) and its components according to Adult Treatment Panel III (ATP III) and International Diabetes Federation (IDF) criteria and the risk factors affecting MS. Metabolic syndrome prevalence was evaluated according to certain quintet age groups, altitude, location and demographic features.

Material and methods: This study was a cross-sectional survey conducted in 24 provinces from the 7 regions of Turkey. A total of 4309 adults from 7 regions participated in the study (1947 males, 45.2%).

Results: The mean age of participants was 47 ±14 years. Metabolic syndrome prevalence was found as 36.6% according to ATP III and 44.0% according to IDF. The MS rate was found to be higher in females compared to males in both groups (p < 0.01). According to both criteria, MS prevalence was found to be higher in subjects who lived in coastal regions when evaluated according to altitude and in subjects who lived in district centers when evaluated according to location. The MS risk is 1.62-fold higher in females compared to males. Metabolic syndrome risk increases as age increases and is highest in the 61-65 age group. Metabolic syndrome risk increases 2.75-fold in the overweight compared to normal weighing subjects and 7.80-fold in the obese.

Conclusions: Metabolic syndrome prevalence was found to be high in Turkey according to both criteria. Metabolic syndrome prevalence increases as age and body mass index (BMI) increase. Age, female gender and obesity are independent risk factors for MS development.

Keywords: age groups; altitude; metabolic syndrome.

Figures

Figure 1
Figure 1
Map of Turkey

References

    1. Ford ES. Prevalence of the metabolic syndrome defined by the International Diabetes Federation among adults in the U.S. Diabetes Care. 2005;28:2745–9.
    1. Laaksonen DE, Lakka HM, Niskanen LK, et al. Metabolic syndrome and development of diabetes mellitus: application and validation of recently suggested definitions of the metabolic syndrome in a prospective cohort study. Am J Epidemiol. 2002;156:1070–7.
    1. Miranda PJ, DeFronzo RA, Califf RM, Guyton JR. Metabolic syndrome: definition, pathophysiology, and mechanisms. Am Heart J. 2005;149:33–45.
    1. Grundy SM, Cleeman JI, Daniels SR, et al. American Heart Association; National Heart, Lung, and Blood Institute. Diagnosis and management of the metabolic syndrome: an American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement. Circulation. 2005;112:2735–52.
    1. Wu SH, Liu Z, Ho SC. Metabolic syndrome and all-cause mortality: a meta-analysis of prospective cohort studies. Eur J Epidemiol. 2010;25:375–84.
    1. Sarrafzadegan N, Kelishadi R, Baghaei A, et al. Metabolic syndrome: an emerging public health problem in Iranian women: Isfahan Healthy Heart Program. Int J Cardiol. 2008;131:90–6.
    1. Alberti KG, Zimmet P, Shaw J. IDF Epidemiology Task Force Consensus Group. The metabolic syndrome: a new worldwide definition. Lancet. 2005;366:1059–62.
    1. Seneff S, Wainwright G, Mascitelli L. Is the metabolic syndrome caused by a high fructose, and relatively low fat, low cholesterol diet? Arch Med Sci. 2011;7:8–20.
    1. Athyros VG, Giouleme O, Ganotakis ES, et al. Safety and impact on cardiovascular events of long-term multifactorial treatment in patients with metabolic syndrome and abnormal liver function tests: a post hoc analysis of the randomised ATTEMPT study. Arch Med Sci. 2011;7:796–805.
    1. Zhu S, St-Onge MP, Heshka S, Heymsfield SB. Lifestyle behaviors associated with lower risk of having the metabolic syndrome. Metabolism. 2004;53:1503–11.
    1. Resnick HE. Strong Heart Study Investigators. Metabolic syndrome in American Indians. Diabetes Care. 2002;25:1246–7.
    1. Balkau B. Smoking, type 2 diabetes and metabolic syndrome. Diabetes Metab. 2004;30:110–1.
    1. Gupta A, Gupta R, Sarna M, et al. Prevalence of diabetes, impaired fasting glucose and insulin resistance syndrome in an urban Indian population. Diabetes Res Clin Pract. 2003;61:69–76.
    1. Gündogan K, Bayram F, Capak M, et al. Prevalence of metabolic syndrome in the Mediterranean region of Turkey: evaluation of hypertension, diabetes mellitus, obesity, and dyslipidemia. Metab Syndr Relat Disord. 2009;7:427–34.
    1. Onat A, Ceyhan K, Başar O, et al. Metabolic syndrome: major impact on coronary risk in a population with low cholesterol levels: a prospective and cross-sectional evaluation. Atherosclerosis. 2002;165:285–92.
    1. Ozsahin AK, Gokcel A, Sezgin N, et al. Prevalence of the metabolic syndrome in a Turkish adult population. Diabetes Nutr Metab. 2004;17:230–4.
    1. Demiral Y, Soysal A, Can Bilgin A, et al. The association of job strain with coronary heart disease and metabolic syndrome in municipal workers in Turkey. J Occup Health. 2006;48:332–8.
    1. Soysal A, Demiral Y, Soysal D, et al. The prevalence of metabolic syndrome among young adults in Izmir, Turkey. Anadolu Kardiyol Derg. 2005;5:196–201.
    1. Eckel RH, Grundy SM, Zimmet PZ. The metabolic syndrome. Lancet. 2005;365:1415–28.
    1. Erem C, Hacihasanoglu A, Deger O, et al. Prevalence of metabolic syndrome and associated risk factors among Turkish adults: Trabzon MetS study. Endocrine. 2008;33:9–20.
    1. Panagiotakos DB, Pitsavos C, Chrysohoou C, et al. Impact of lifestyle habits on the prevalence of the metabolic syndrome among Greek adults from the ATTICA study. Am Heart J. 2004;147:106–12.
    1. Cankurtaran M, Halil M, Yavuz BB, Dagli N, Oyan B, Ariogul S. Prevalence and correlates of metabolic syndrome (MS) in older adults. Arch Gerontol Geriatr. 2006;42:35–45.
    1. Athyros VG, Bouloukos VI, Pehlivanidis AN, et al. MetS-Greece Collaborative Group. The prevalence of the metabolic syndrome in Greece: the MetS-Greece Multicentre Study. Diabetes Obes Metab. 2005;7:397–405.
    1. Delavari A, Forouzanfar MH, Alikhani S, Sharifian A, Kelishadi R. First nationwide study of the prevalence of the metabolic syndrome and optimal cutoff points of waist circumference in the Middle East: the national survey of risk factors for noncommunicable diseases of Iran. Diabetes Care. 2009;32:1092–7.
    1. O'Neil CE, Fulgoni VL, 3rd, Nicklas TA. Candy consumption was not associated with body weight measures, risk factors for cardiovascular disease, or metabolic syndrome in US adults: NHANES 1999-2004. Nutr Res. 2011;31:122–30.
    1. Ozsait B, Kömürcü Bayrak E, Poda M, et al. CETP TaqIB polymorphism in Turkish adults: association with dyslipidemia and metabolic syndrome. Anadolu Kardiyol Derg. 2008;8:324–30.
    1. Kraja AT, Rao DC, Weder AB, et al. An evaluation of the metabolic syndrome in a large multi-ethnic study: the Family Blood Pressure Program. Nutr Metab (Lond) 2005;2:17.
    1. Scholze J, Alegria E, Ferri C, et al. Epidemiological and economic burden of metabolic syndrome and its consequences in patients with hypertension in Germany, Spain and Italy: a prevalence-based model. BMC Public Health. 2010;10:529.
    1. Sidorenkov O, Nilssen O, Grjibovski AM. Metabolic syndrome in Russian adults: associated factors and mortality from cardiovascular diseases and all causes. BMC Public Health. 2010;10:582.
    1. Al Suwaidi J, Zubaid M, El-Menyar AA, et al. Prevalence of the metabolic syndrome in patients with acute coronary syndrome in six Middle Eastern Countries. J Clin Hypertens (Greenwich) 2010;12:890–9.
    1. Saito I, Mori M, Shibata H, Hirose H, Tsujioka M, Kawabe H. Prevalence of metabolic syndrome in young men in Japan. J Atheroscler Thromb. 2007;14:27–30.
    1. Wang L, Tao Y, Xie Z, et al. Prevalence of metabolic syndrome, insulin resistance, impaired fasting blood glucose, and dyslipidemia in Uygur and Kazak populations. J Clin Hypertens (Greenwich) 2010;12:741–5.
    1. Shuval K, DeVahl J, Tong L, Gimpel N, Lee JJ, DeHaven MJ. Anthropometric measures, presence of metabolic syndrome, and adherence to physical activity guidelines among African American church members, Dallas, Texas, 2008. Prev Chronic Dis. 2011;8:A18.
    1. du Plessis A, Malan L, Malan NT. Coping and metabolic syndrome indicators in urban black South African men: the SABPA study. Cardiovasc J Afr. 2010;21:268–73.
    1. Sobngwi E, Mbanya JC, Unwin NC, et al. Physical activity and its relationship with obesity, hypertension and diabetes in urban and rural Cameroon. Int J Obes Relat Metab Disord. 2002;26:1009–16.
    1. Erem C, Hacihasanoglu A, Deger O, Kocak M, Topbas M. Prevalence of dyslipidemia and associated risk factors among Turkish adults: Trabzon lipid study. Endocrine. 2008;34:36–51.
    1. 25.TURKSTAT, Income and Living Conditions Survey, 200-2009.
    1. Alberti KG, Eckel RH, Grundy SM, et al. International Diabetes Federation Task Force on Epidemiology and Prevention; Hational Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International Atherosclerosis Society; International Association for the Study of Obesity. Harmonizing the metabolic syndrome: a joint interim statement of the International Diabetes Federation Task Force on Epidemiology and Prevention; National Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International Atherosclerosis Society; and International Association for the Study of Obesity. Circulation. 2009;120:1640–5.
    1. Sanisoglu SY, Oktenli C, Hasimi A, Yokusoglu M, Ugurlu M. Prevalence of metabolic syndrome-related disorders in a large adult population in Turkey. BMC Public Health. 2006;6:92.
    1. Can AS, Bersot TP. Analysis of agreement among definitions of metabolic syndrome in nondiabetic Turkish adults: a methodological study. BMC Public Health. 2007;7:353.
    1. Zabetian A, Hadaegh F, Azizi F. Prevalence of metabolic syndrome in Iranian adult population, concordance between the IDF with the ATPIII and the WHO definitions. Diabetes Res Clin Pract. 2007;77:251–7.
    1. Athyros VG, Ganotakis ES, Elisaf M, Mikhailidis DP. The prevalence of the metabolic syndrome using the National Cholesterol Educational Program and International Diabetes Federation definitions. Curr Med Res Opin. 2005;21:1157–9.
    1. Moy FM, Bulgiba A. The modified NCEP ATP III criteria maybe better than the IDF criteria in diagnosing Metabolic Syndrome among Malays in Kuala Lumpur. BMC Public Health. 2010;10:678.
    1. Gokcel A, Ozsahin AK, Sezgin N, et al. High prevalence of diabetes in Adana, a southern province of Turkey. Diabetes Care. 2003;26:3031–4.
    1. Erem C, Arslan C, Hacihasanoglu A, et al. Prevalence of obesity and associated risk factors in a Turkish population (Trabzon city, Turkey) Obes Res. 2004;12:1117–27.
    1. Jaber LA, Brown MB, Hammad A, Zhu Q, Herman WH. The prevalence of the metabolic syndrome among Arab Americans. Diabetes Care. 2004;27:234–8.

Source: PubMed

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