[Profile characterization of Parkinson's disease in Mexico: ReMePARK study]

Amin Cervantes-Arriaga, Mayela Rodríguez-Violante, Minerva López-Ruiz, Ingrid Estrada-Bellmann, Carlos Zuñiga-Ramírez, Elisa Otero-Cerdeira, Azyadeh Camacho-Ordoñez, Paulina González-Latapi, Hugo Morales-Briceño, Daniel Martínez-Ramírez, Amin Cervantes-Arriaga, Mayela Rodríguez-Violante, Minerva López-Ruiz, Ingrid Estrada-Bellmann, Carlos Zuñiga-Ramírez, Elisa Otero-Cerdeira, Azyadeh Camacho-Ordoñez, Paulina González-Latapi, Hugo Morales-Briceño, Daniel Martínez-Ramírez

Abstract

Introduction: The Mexican Registry of Parkinson´s disease (ReMePARK) is nested within a multicentric cohort aimed to describe motor, non-motor, and genetic determinants of Parkinson's disease in Mexican patients.

Material and methods: To date, clinical and demographic data from 1,083 subjects has been obtained. Here we present the demographic and clinical data of the current sample along with its comparison with international reports.

Results: A total of 607 male and 476 female subjects with Parkinson's disease were included. The mean age of the patients was 64.7 ± 12.9 years. The time from onset of symptoms to diagnosis was 2.4 ± 2.6 years. About 34% of subjects had only elementary education. Of the subjects, 54.4% were under treatment with dopamine agonists.

Conclusion: Subjects with Parkinson's disease incorporated into ReMePARK are comparable with other international registries, with the exception of the years of formal education, time to diagnosis, and the use of dopamine agonists. The characterization of the Mexican population with Parkinson's disease will improve diagnosis and therapeutic management as well as define research efforts in this area. Finally, registry future directions are presented.

Source: PubMed

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