Pain Management for Total Knee Arthroplasty: Single-Injection Femoral Nerve Block versus Local Infiltration Analgesia

Mehdi Moghtadaei, Hossein Farahini, Seyed Hamid-Reza Faiz, Farzam Mokarami, Saeid Safari, Mehdi Moghtadaei, Hossein Farahini, Seyed Hamid-Reza Faiz, Farzam Mokarami, Saeid Safari

Abstract

Background: Pain is one of the major concerns of patients underwent Total Knee Arthroplasty (TKA); appropriate pain management is a key factor in patient's early physical fitness to move, physiotherapy, and most importantly, patient satisfaction.

Objectives: In this study the analgesic effect of single injection femoral nerve block (SFNB) was compared with local infiltration analgesia (LIA).

Patients and methods: Forty patients who underwent TKA under spinal anesthesia were randomized to receive single femoral nerve block (group F) or intra-periarticular infiltration (group I). Group F received single injection 20cc ropivacaine (10mg/cc) and in group I, a combination of 300mg ropivacaine, 30mg ketorolac and 0.5mg epinephrine diluted to a volume of 150cc and locally injected in and around the knee joint in 3 stages. Postoperative pain intensity measured by Visual Analog Scale (VAS). Morphine consumption, mobilization time and patients' satisfaction evaluated as well.

Results: Group I had significantly lower morphine consumption in the first postoperative day (10 vs. 12.5mg, P-value < 0.05). Within 6 hours postoperatively, VAS score was statistically lower in group I compared to group F (3 vs. 4, P-value < 0.05). However, within 12 hours it was statistically higher in group I than group F (6 vs. 5, P-value < 0.05). Other parameters were not statistically different in two groups.

Conclusions: Both methods LIA and SFNB provided excellent pain relief and lower morphine consumption following TKA. LIA is a surgeon-controlled analgesic technique, which can be used to enhance patients' satisfaction and reduce the pain in the very early postoperative period by surgeon independently.

Keywords: Analgesia; Femoral Nerve Block; Local Infiltration Analgesia; Morphine.

Figures

Figure 1.. Consort Flow Diagram of Patients…
Figure 1.. Consort Flow Diagram of Patients Through the Study
Figure 2.. Injection Before Prosthesis Placement
Figure 2.. Injection Before Prosthesis Placement
Figure 3.. Injection After Prosthesis Placement
Figure 3.. Injection After Prosthesis Placement

References

    1. Paul JE, Arya A, Hurlburt L, Cheng J, Thabane L, Tidy A, et al. Femoral nerve block improves analgesia outcomes after total knee arthroplasty: a meta-analysis of randomized controlled trials. Anesthesiology. 2010;113(5):1144–62. doi: 10.1097/ALN.0b013e3181f4b18.
    1. Centers for Disease Control. Racial disparities in total knee replacement among Medicare enrollees--United States, 2000-2006. MMWR Morb Mortal Wkly Rep. 2009;58(6):133–8.
    1. Lang SA. Postoperative analgesia following total knee arthroplasty: a study comparing spinal anesthesia and combined sciatic femoral 3-in-1 block. Reg Anesth Pain Med. 1999;24(1):97.
    1. Imani F, Safari S. Pain Relief is an Essential Human Right”, We Should be Concerned about It. Anesth Pain Med. 2011;1(2):55–7. doi: 10.5812/kowsar.22287523.2306.
    1. Nussenzveig TC. Pain management after total joint replacement and its impact on patient outcomes. Aorn J. 1999;70(6):1060–2.
    1. Singelyn FJ, Deyaert M, Joris D, Pendeville E, Gouverneur JM. Effects of intravenous patient-controlled analgesia with morphine, continuous epidural analgesia, and continuous three-in-one block on postoperative pain and knee rehabilitation after unilateral total knee arthroplasty. Anesth Analg. 1998;87(1):88–92.
    1. Seet E, Leong WL, Yeo AS, Fook-Chong S. Effectiveness of 3-in-1 continuous femoral block of differing concentrations compared to patient controlled intravenous morphine for post total knee arthroplasty analgesia and knee rehabilitation. Anaesth Intensive Care. 2006;34(1):25–30.
    1. Duarte VM, Fallis WM, Slonowsky D, Kwarteng K, Yeung CK. Effectiveness of femoral nerve blockade for pain control after total knee arthroplasty. J Perianesth Nurs. 2006;21(5):311–6. doi: 10.1016/j.jopan.2006.05.011.
    1. Fowler SJ, Symons J, Sabato S, Myles PS. Epidural analgesia compared with peripheral nerve blockade after major knee surgery: a systematic review and meta-analysis of randomized trials. Br J Anaesth. 2008;100(2):154–64. doi: 10.1093/bja/aem373.
    1. Amiri HR, Safari S, Makarem J, Rahimi M, Jahanshahi B. Comparison of combined femoral nerve block and spinal anesthesia with lumbar plexus block for postoperative analgesia in intertrochanteric fracture surgery. Anesth Pain Med. 2012;2(1):32–5. doi: 10.5812/aapm.4526.
    1. Ben-David B, Chelly JE. Continuous peripheral neural blockade for postoperative analgesia: practical advantages. Anesth Analg. 2003;96(5):1537.
    1. Fischer HB, Simanski CJ, Sharp C, Bonnet F, Camu F, Neugebauer EA, et al. A procedure-specific systematic review and consensus recommendations for postoperative analgesia following total knee arthroplasty. Anaesthesia. 2008;63(10):1105–23. doi: 10.1111/j.1365-2044.2008.05565.x.
    1. Lee RM, Tey JBL, Chua NHL. Postoperative Pain Control for Total Knee Arthroplasty: Continuous Femoral Nerve Block Versus Intravenous Patient Controlled Analgesia. Anesth Pain Med. 2012;1(4):239–42. doi: 10.5812/aapm.3404.
    1. Kerr DR, Kohan L. Local infiltration analgesia: a technique for the control of acute postoperative pain following knee and hip surgery: a case study of 325 patients. Acta Orthop. 2008;79(2):174–83. doi: 10.1080/17453670710014950.
    1. Carli F, Clemente A, Asenjo JF, Kim DJ, Mistraletti G, Gomarasca M, et al. Analgesia and functional outcome after total knee arthroplasty: periarticular infiltration vs continuous femoral nerve block. Br J Anaesth. 2010;105(2):185–95. doi: 10.1093/bja/aeq112.
    1. Andersen KV, Bak M, Christensen BV, Harazuk J, Pedersen NA, Soballe K. A randomized, controlled trial comparing local infiltration analgesia with epidural infusion for total knee arthroplasty. Acta Orthop. 2010;81(5):606–10. doi: 10.3109/17453674.2010.519165.
    1. Toftdahl K, Nikolajsen L, Haraldsted V, Madsen F, Tonnesen EK, Soballe K. Comparison of peri- and intraarticular analgesia with femoral nerve block after total knee arthroplasty: a randomized clinical trial. Acta Orthop. 2007;78(2):172–9. doi: 10.1080/17453670710013645.
    1. Essving P, Axelsson K, Kjellberg J, Wallgren O, Gupta A, Lundin A. Reduced morphine consumption and pain intensity with local infiltration analgesia (LIA) following total knee arthroplasty. Acta Orthop. 2010;81(3):354–60. doi: 10.3109/17453674.2010.487241.
    1. Salinas FV, Liu SS, Mulroy MF. The effect of single-injection femoral nerve block versus continuous femoral nerve block after total knee arthroplasty on hospital length of stay and long-term functional recovery within an established clinical pathway. Anesth Analg. 2006;102(4):1234–9. doi: 10.1213/01.ane.0000198675.20279.81.
    1. Shoar S, Esmaeili S, Safari S. Pain Management After Surgery: A Brief Review. Anesth Pain Med. 2012;1(3):184–6. doi: 10.5812/kowsar.22287523.3443.
    1. Liu SS, Richman JM, Thirlby RC, Wu CL. Efficacy of continuous wound catheters delivering local anesthetic for postoperative analgesia: a quantitative and qualitative systematic review of randomized controlled trials. J Am Coll Surg. 2006;203(6):914–32. doi: 10.1016/j.jamcollsurg.2006.08.007.
    1. Choy WS, Lee SK, Kim KJ, Kam BS, Yang DS, Bae KW. Two continuous femoral nerve block strategies after TKA. Knee Surg Sports Traumatol Arthrosc. 2011;19(11):1901–8. doi: 10.1007/s00167-011-1510-4.
    1. Cuvillon P, Ripart J, Lalourcey L, Veyrat E, L'Hermite J, Boisson C, et al. The continuous femoral nerve block catheter for postoperative analgesia: bacterial colonization, infectious rate and adverse effects. Anesth Analg. 2001;93(4):1045–9.
    1. Rosenberg PH, Veering BT, Urmey WF. Maximum recommended doses of local anesthetics: a multifactorial concept. Reg Anesth Pain Med. 2004;29(6):564–75. discussion 524.
    1. Motavaf M, Safari S, Alavian SM. Understanding of molecular pain medicine: genetic basis of variation in pain sensation and analgesia response. Anesth Pain Med. 2013;2(3):104–6. doi: 10.5812/aapm.8583.

Source: PubMed

3
Subscribe