Elevated aspartate aminotransferase-to-platelet ratio index in perinatally HIV-infected children in the United States
George K Siberry, Kunjal Patel, Jorge A Pinto, Ana Puga, Ayesha Mirza, Tracie L Miller, Russell B Van Dyke, Pediatric HIVAIDS Cohort Study, George K Siberry, Kunjal Patel, Jorge A Pinto, Ana Puga, Ayesha Mirza, Tracie L Miller, Russell B Van Dyke, Pediatric HIVAIDS Cohort Study
Abstract
Elevated aspartate aminotransferase-to-platelet ratio index may signal liver fibrosis. Among 397 US children with perinatal HIV infection, at baseline was >1.5 in 0.8% [95% confidence interval (CI), 0.2-2.2%) and >0.5 in 6.5% (95% CI, 4.3-9.4%); incidence on study was 0.5 (95% CI, 0.2-1.2) and 6.4 (95% CI, 4.8-8.3) per 100 person-years, respectively. Long-term liver outcomes after perinatal HIV infection warrant further study.
Source: PubMed