Prevalence of periodontal diseases in a multicenter cohort of perinatally HIV-infected and HIV-exposed and uninfected youth
Mark I Ryder, Tzy-Jyun Yao, Jonathan S Russell, Anna-Barbara Moscicki, Caroline H Shiboski, Pediatric HIV/AIDS Cohort Study, Ester Yang, William Shearer, Mary Paul, Norma Cooper, Lynette Harris, Karen Kemp-Posterman, Selene Wun, Murli Purswani, Mahboobullah Baig, Anna Cintron, Jennifer Zeni, Ana Puga, Sandra Navarro, Doyle Patton, Deyana Leon, Man Wai Ng, Sandra Burchett, Nancy Karthas, Betsy Kammerer, Ray Jurado, Johnny Kuttab, Ashlee Vorachek, Ram Yogev, Margaret Ann Sanders, Kathleen Malee, Scott Hunter, Victor Badner, Ronald Garreett, Andrew Wiznia, Marlene Burey, Molly Nozyce, Susan Chialastri, Janet Chen, Latreca Ivey, Maria Garcia Bulkley, Mitzie Grant, Ramon Gonzalez, Midnela Acevedo-Flores, Heida Rios, Vivian Olivera, Janice Townsend, Margarita Silio, Medea Jones, Patricia Sirois, Roopa Gandhi, Elizabeth McFarland, Emily Barr, Robin McEvoy, Kenneth Markowitz, Arry Dieudonne, Linda Bettica, Susan Adubato, Mark I Ryder, Tzy-Jyun Yao, Jonathan S Russell, Anna-Barbara Moscicki, Caroline H Shiboski, Pediatric HIV/AIDS Cohort Study, Ester Yang, William Shearer, Mary Paul, Norma Cooper, Lynette Harris, Karen Kemp-Posterman, Selene Wun, Murli Purswani, Mahboobullah Baig, Anna Cintron, Jennifer Zeni, Ana Puga, Sandra Navarro, Doyle Patton, Deyana Leon, Man Wai Ng, Sandra Burchett, Nancy Karthas, Betsy Kammerer, Ray Jurado, Johnny Kuttab, Ashlee Vorachek, Ram Yogev, Margaret Ann Sanders, Kathleen Malee, Scott Hunter, Victor Badner, Ronald Garreett, Andrew Wiznia, Marlene Burey, Molly Nozyce, Susan Chialastri, Janet Chen, Latreca Ivey, Maria Garcia Bulkley, Mitzie Grant, Ramon Gonzalez, Midnela Acevedo-Flores, Heida Rios, Vivian Olivera, Janice Townsend, Margarita Silio, Medea Jones, Patricia Sirois, Roopa Gandhi, Elizabeth McFarland, Emily Barr, Robin McEvoy, Kenneth Markowitz, Arry Dieudonne, Linda Bettica, Susan Adubato
Abstract
Aims: To compare the prevalence and severity of periodontal diseases between 180 perinatally HIV-infected (PHIV) and 118 perinatally HIV-exposed and uninfected (PHEU) youth in a cross-sectional study conducted at 11 clinical sites in the United States and Puerto Rico from the Adolescent Master Protocol study of the Pediatric HIV/AIDS cohort study (PHACS) network.
Methods: Several analyses were conducted, employing the current CDC/AAP classification for periodontitis and incorporating a definition of gingivitis based on a bleeding on probing (BOP) threshold, and analyses based on more detailed whole-mouth, intra-oral regionally, site-based and tooth-based criteria of BOP, plaque levels, pockets depths and clinical attachment levels.
Results: After adjusting for plaque control habits and behavioural and sociodemographic factors, there were no significant differences in periodontal diseases between the PHIV and PHEU youth using any of these criteria. For PHIV youth, there was no significant association between parameters of periodontal disease and current HIV status.
Conclusions: Although no significant differences in periodontal parameters were noted between the PHIV and PHEU youth, the influence of antiretroviral therapy merits further exploration in this cohort in a longitudinal study.
Keywords: HIV; gingivitis; periodontal disease; youth.
© 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.
Source: PubMed