Effect of infraorbital nerve block on postoperative pain and 30-day morbidity at the donor site in buccal mucosal graft urethroplasty

Nirmala Jonnavithula, Deepak Bachu, Vidyasagar Sriramoju, Rahul Devraj, Ramachandraiah Gunta, Murthy V L N Pisapati, Nirmala Jonnavithula, Deepak Bachu, Vidyasagar Sriramoju, Rahul Devraj, Ramachandraiah Gunta, Murthy V L N Pisapati

Abstract

Background and aims: Buccal mucosa harvest for substitution urethroplasty can be painful, and may be associated with long-term complications such as perioral numbness, persistent difficulty with mouth opening, and change in salivary function. This study was designed to evaluate the efficacy of infraorbital nerve block (IOB) in relieving postoperative pain at the donor site of the buccal mucosal graft (BMG) and its associated morbidity at 30 days.

Material and methods: Thirty adults scheduled for BMG urethroplasty were enrolled in this study and were randomized to receive either no block group I (control) and IOB group II intraorally with 1 mL of 0.5% bupivacaine. Pain was assessed by visual analog scale, intraoral morbidity, and patient satisfaction in the immediate postoperative period. All patients were reviewed after 1 month for morbidity such as perioral numbness, pain on mastication, and tightness on mouth opening. Statistical analysis was done using Mann-Whitney's U and Chi-square tests.

Results: Median time to pain-free oral intake for liquids (group I: 2-5 days, group II: 1 day, P < 0.001) and solids (group I: 4 days, group II: 2 days, P < 0.001) was earlier in group II. At the follow-up after 1 month, one patient in group II and three patients in group I showed perioral numbness (P = 0.026), and five patients had pain on mastication in group I (P = 0.016).

Conclusion: IOB is associated with postoperative analgesia and facilitation of early food intake, mitigating the morbidity of the donor site and provides satisfaction.

Keywords: Analgesia; buccal mucosal graft; nerve block.

Conflict of interest statement

There are no conflicts of interest.

Figures

Figure 1
Figure 1
Box plot graph showing pain scores at different intervals of time

References

    1. Tolstunov L, Pogrel MA, McAninch JW. Intraoral morbidity following free buccal mucosal graft harvesting for urethroplasty. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1997;84:480–2.
    1. Wood DN, Allen SE, Andrich DE, Greenwell TJ, Mundy AR. The morbidity of buccal mucosal graft harvest site on postoperative pain. J Urol. 2004;172:580–3.
    1. Schlondorff D. Renal complications of non steroidal anti inflammatory drugs. Kidney Int. 1993;44:643–53.
    1. Richman JM, Liu SS, Courpas G, Wong R, Rowlingson AJ, McGready J, et al. Does continuous peripheral nerve block provide superior pain control to opioids? A meta-analysis. Anesth Analg. 2006;102:248–57.
    1. Jonnavithula N, Durga P, Kulkarni DK, Ramachandran G. Bilateral intraoral, infraorbital nerve block for postoperative analgesia following cleft lip repair in pediatric patients. Comparison of bupivacaine vs bupivacaine-pethidine combination. Anaesthesia. 2007;62:581–5.
    1. Edward RM, Deborah W, Vanessa JL, Larry FC, Gloria SC, Sach HM, et al. Bilateral infraorbital nerve block decrease pain but not reduce time to discharge following outpatient nasal surgery. Can J Anaesth. 2009;56:584–9.
    1. McAdam D, Muro K, Suresh S. The use of infraorbital nerve block for postoperative pain control after transsphenoidal hypophysectomy. Reg Anesth Pain Med. 2005;6:572–3.
    1. Perkins FM, Kehlet H. Chronic pain as an outcome of surgery: A review of predictive factors. Anesthesiology. 2000;93:1123–33.
    1. Jamison RN, Ross MJ, Hoopman P, Griffin F, Levy J, Daly M. Assessment of postoperative pain management: Patient satisfaction and perceived helpfulness. Clin J Pain. 1997;13:229–36.
    1. Barbagli G, Palminteri E, Destefanis, Lazzeri M. Harvesting buccal mucosal grafts. Key to success. Contemp Urol. 2006;18:16–24.
    1. Fichtner J, Filipas D, Fisch M, Hohenfellner R, Thuroff JW. Long- term outcome of ventral buccal mucosa onlay graft urethroplasty for urethral stricture repair. Urology. 2004;64:648–50.
    1. Dublin N, Stewart LH. Oral complications after buccal mucosal graft harvest for urethroplasty. BJU Int. 2004;94:867–9.
    1. Kehlet H, Jensen TS, Woolf CJ. Persistent postsurgical pain: Risk factors and prevention. Lancet. 2006;367:1618–25.
    1. Dodure C, Sola C, Dalens B, Capdevila X. Regional anesthesia in children. In: Miller RD, editor. Miller's Anesthesia. 8th ed. Philadelphia: Elsevier Saunders; 2015. pp. 2147–8.
    1. Suresh S, Jagannathan S. Somatic blockade of head and neck. In: Cousins MJ, Carr DB, Horlocker TT, Bridenbaugh PD, editors. Cousins and Bridenbaughs neural blockade in clinical anesthesia and pain medicine. 4th ed. Wolters Kluwer, Lippincott Williams and Wilkins; 2009. pp. 405–26. 3.
    1. Igor K. Preemptive analgesia. Anesthesiology. 2000;93:1138–43.
    1. Capdevila X, Barthelet Y, Biboulet P, Ryckwaert Y, Rubenovitch J, d’Athis F. Effects of perioperative analgesic technique on the surgical outcome and duration of rehabilitation after major knee surgery. Anesthesiology. 1999;91:8–15.
    1. Capdevila X, Barthelet Y, Biboulet P, Ryckwaert Y, Rubenovitch J, d’Athis F, et al. Continuous peripheral nerve blocks in clinical practice. Curr Opin Anaesthesiol. 2008;21:619–23.
    1. Morrison RS, Flanagan S, Fischberg D, Cintron A, Siu AL. A novel interdisciplinary analgesic program reduces pain and improves function in older adults after orthopaedic surgery. J Am Geriatr Soc. 2009;57:1–10.
    1. Jonnavithula N, Khandelia H, Durga P, Ramachandran G. Role of wound instillation with bupivacaine through surgical drains for postoperative analgesia in modified radical mastectomy. Indian J Anaesth. 2015;59:15–20.
    1. Jonnavithula N, Durga P, Madduri V, Ramachandran G, Nuvvula R, Srikanth R, et al. Efficacy of palatal block for analgesia following palatoplasty in children with cleft palate. Paediatr Anaesth. 2010;20:727–33.

Source: PubMed

3
Subscribe