Commentary: Relationship between Milk Microbiota, Bacterial Load, Macronutrients, and Human Cells during Lactation

Tanja Obermajer, Tomislav Pogačić, Tanja Obermajer, Tomislav Pogačić

No abstract available

Keywords: diversity; ecosystem homeostasis; functionality; human colostrum; human milk; microbial interactions; microbiota.

Figures

Figure 1
Figure 1
Schematic presentation summarizing the discussed current research work and proposed future research directions.

References

    1. Arroyo R., Martín V., Maldonado A., Jiménez E., Fernández L., Rodríguez J. M. (2010). Treatment of infectious mastitis during lactation: antibiotics versus oral administration of lactobacilli isolated from breast milk. Clin. Infect. Dis. 50, 1551–1558. 10.1086/652763
    1. Bäckhed F., Roswall J., Peng Y., Feng Q., Jia H., Kovatcheva-Datchary P., et al. . (2015). Dynamics and stabilization of the human gut microbiome during the first year of life. Cell Host Microbe 17, 690–703. 10.1016/j.chom.2015.04.004
    1. Benítez-Páez A., Belda-Ferre P., Simón-Soro A., Mira A. (2014). Microbiota diversity and gene expression dynamics in human oral biofilms. BMC Genomics 15:311. 10.1186/1471-2164-15-311
    1. Boix-Amorós A., Collado M. C., Mira A. (2016). relationship between milk microbiota, bacterial load, macronutrients, and human cells during lactation. Front. Microbiol. 7:492. 10.3389/fmicb.2016.00492
    1. Chan A. A., Bashir M., Rivas M. N., Duvall K., Sieling P. A., Pieber T. R., et al. . (2016). Characterization of the microbiome of nipple aspirate fluid of breast cancer survivors. Sci. Rep. 6:28061. 10.1038/srep28061
    1. Chow J., Panasevich M. R., Alexander D., Vester Boler B. M., Rossoni Serao M. C., Faber T. A., et al. . (2014). Fecal metabolomics of healthy breast-fed versus formula-fed infants before and during in vitro batch culture fermentation. J. Proteome Res. 13, 2534–2542. 10.1021/pr500011w
    1. Delgado S., Arroyo R., Martín R., Rodríguez J. M. (2008). PCR-DGGE assessment of the bacterial diversity of breast milk in women with lactational infectious mastitis. BMC Infect. Dis. 8:51. 10.1186/1471-2334-8-51
    1. Dogra S., Sakwinska O., Soh S.-E., Ngom-Bru C., Brück W. M., Berger B., et al. . (2015). Rate of establishing the gut microbiota in infancy has consequences for future health. Gut Microbes 6, 321–325. 10.1080/19490976.2015.1078051
    1. Hassiotou F., Hepworth A. R., Metzger P., Tat Lai C., Trengove N., Hartmann P. E., et al. . (2013). Maternal and infant infections stimulate a rapid leukocyte response in breastmilk. Clin. Transl. Immunol. 2:e3. 10.1038/cti.2013.1
    1. Hunt K. M., Preuss J., Nissan C., Davlin C. A., Williams J. E., Shafii B., et al. . (2012). Human milk oligosaccharides promote the growth of staphylococci. Appl. Environ. Microbiol. 78, 4763–4770. 10.1128/AEM.00477-12
    1. Hunt K. M., Williams J. E., Shafii B., Hunt M. K., Behre R., Ting R., et al. . (2013). Mastitis is associated with increased free fatty acids, somatic cell count, and interleukin-8 concentrations in human milk. Breastfeed. Med. Off. J. Acad. Breastfeed. Med. 8, 105–110. 10.1089/bfm.2011.0141
    1. Jiménez E., de Andrés J., Manrique M., Pareja-Tobes P., Tobes R., Martínez-Blanch J. F., et al. . (2015). Metagenomic analysis of milk of healthy and mastitis-suffering women. J. Hum. Lact. 31, 406–415. 10.1177/0890334415585078
    1. Lewis Z. T., Totten S. M., Smilowitz J. T., Popovic M., Parker E., Lemay D. G., et al. . (2015). Maternal fucosyltransferase 2 status affects the gut bifidobacterial communities of breastfed infants. Microbiome 3:13. 10.1186/s40168-015-0071-z
    1. Loozen G., Ozcelik O., Boon N., De Mol A., Schoen C., Quirynen M., et al. . (2014). Inter-bacterial correlations in subgingival biofilms: a large-scale survey. J. Clin. Periodontol. 41, 1–10. 10.1111/jcpe.12167
    1. Ma Z. S., Guan Q., Ye C., Zhang C., Foster J. A., Forney L. J. (2015). Network analysis suggests a potentially “evil” alliance of opportunistic pathogens inhibited by a cooperative network in human milk bacterial communities. Sci. Rep. 5:8275. 10.1038/srep08275
    1. Ma Z. S., Li L., Li W., Li J., Chen H. (2016). Integrated network-diversity analyses suggest suppressive effect of Hodgkin's lymphoma and slightly relieving effect of chemotherapy on human milk microbiome. Sci. Rep. 6:28048. 10.1038/srep28048
    1. Moya A., Ferrer M. (2016). Functional redundancy-induced stability of gut microbiota subjected to disturbance. Trends Microbiol. 24, 402–413. 10.1016/j.tim.2016.02.002
    1. Obermajer T., Lipoglavšek L., Tompa G., Treven P., Lorbeg P. M., Matijašić B. B., et al. . (2015). Colostrum of healthy slovenian mothers: microbiota composition and bacteriocin gene prevalence. PLoS ONE 10:e0123324. 10.1371/journal.pone.0123324
    1. Peterson C. T., Sharma V., Elmén L., Peterson S. N. (2015). Immune homeostasis, dysbiosis and therapeutic modulation of the gut microbiota. Clin. Exp. Immunol. 179, 363–377. 10.1111/cei.12474
    1. Scano P., Murgia A., Demuru M., Consonni R., Caboni P. (2016). Metabolite profiles of formula milk compared to breast milk. Food Res. Int. 87, 76–82. 10.1016/j.foodres.2016.06.024
    1. Urbaniak C., Gloor G. B., Brackstone M., Scott L., Tangney M., Reid G. (2016). The microbiota of breast tissue and its association with breast cancer. Appl. Environ. Microbiol. 82, 5039–5048. 10.1128/AEM.01235-16
    1. Ward T. L., Hosid S., Ioshikhes I., Altosaar I. (2013). Human milk metagenome: a functional capacity analysis. BMC Microbiol. 13:116. 10.1186/1471-2180-13-116

Source: PubMed

3
Subscribe