Use of ultrasound guided single shot costotransverse block (intertransverse process) in breast cancer surgery: a prospective, randomized, assessor blinded, controlled clinical trial

Hakan Aygun, Ilker Kiziloglu, Nilgun Kavrut Ozturk, Haydar Ocal, Abdullah Inal, Leyla Kutlucan, Edip Gonullu, Serkan Tulgar, Hakan Aygun, Ilker Kiziloglu, Nilgun Kavrut Ozturk, Haydar Ocal, Abdullah Inal, Leyla Kutlucan, Edip Gonullu, Serkan Tulgar

Abstract

Background: Ultrasound guided costotransverse block (CTB) is a relatively new "peri-paravertebral" block that has been described recently. It has been previously reported that CTB, administered with a single high-volume injection, provides effective analgesia in breast conserving surgery. In this study we evaluated the effect of CTB when used in breast cancer surgery.

Methods: Seventy patients due to undergo breast cancer surgery were included in this blinded, prospective, randomized, efficiency study. Patients were randomized into two equal groups (CTB group and control group) using the closed envelope technique. All patients underwent general anesthesia. In addition to standard analgesia methods, patients in group CTB also received CTB block while the remaining (control group) did not. Numeric rating (pain) scores and opioid consumption was compared between the two groups.

Results: Opioid consumption in all time frames and pain scores at 1st and 3rd hours only were found to be significantly lower in Group CTB when compared to the control group.

Conclusions: Ultrasound guided CTB improves analgesia quality in breast cancer surgery.

Trial registration: Clinicaltrials Registration ID: NCT04197206 , Registration Date: 13/12/2019.

Keywords: Breast cancer; Nerve Block; Postoperative Pain.

Conflict of interest statement

None.

© 2022. The Author(s).

Figures

Fig. 1
Fig. 1
CONSORT flow diagram of study
Fig. 2
Fig. 2
Ultrasound anatomy of costotransverse block
Fig. 3
Fig. 3
Kaplan-Meier analysis of the first opioid requirement of patients

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