Epidemiology of childhood cancer

Benedetto Terracini, Benedetto Terracini

Abstract

At least in economically developed countries, in the last decades, the incidence of childhood cancer has increased and the increase is unlikely to be an artefact. Causes of the increase have not been identified: a role of preventable environmental exposures is possible. Changes have also occurred in the age distribution of acute lymphoblastic leukaemia.Currently, children with cancer can be successfully treated and cured. However, access to the best therapy differs widely among countries because of the unequal distribution of resources for cancer care. Any double standard in the fate of children with cancer is ethically unacceptable.

© 2011 Terracini; licensee BioMed Central Ltd.

References

    1. Tomatis L, Narod S, Yamasaki H. Transgeneration trasmission of carcinogenic risk. Carcinogenesis. 1992;13:145–151. doi: 10.1093/carcin/13.2.145.
    1. Davidoff AM. Pediatric oncology. Semin Pediatr Surg. 2010;19:225–233. doi: 10.1053/j.sempedsurg.2010.03.007.
    1. Yamasaki H, Lokttionov A, Tomatis L. Perinatal and multigenerational effect of carcinogens: possible contribution to determination of cancer susceptibility. Environ Health Perspect. 1992;98:39–43. doi: 10.2307/3431245.
    1. Tomatis L. Overview of perinatal and multigeneration carcinogenesis. IARC Sci Publ. 1992;96:1–15.
    1. Tomatis L. Overview of perinatal and multigeneration carcinogenesis. IARC Sci Publ. 1992;96:1–15.
    1. Steliarova-Foucher E, Stiller C, Kaatsch P, Berrino F, Coebergh JW, Lacour B, Parkin M. Geographical patterns and time trends of cancer incidence and survival among children and adolescents in Europe since the 1970s (the ACCIS project): an epidemiological study. Lancet. 2004;364:2097–2105. doi: 10.1016/S0140-6736(04)17550-8.
    1. Kroll ME, Draper GJ, Stiller CA, Murphy MF. Childhood leukaemia incidence in Britain, 1974-2000: time trends and possible relation to influenza epidemics. J Natl Cancer Inst. 2008;98:417–420.
    1. Greaves M, Buffler PA. Infections in early life and risk of childhood ALL. Br J Cancer. 2009;100:863. doi: 10.1038/sj.bjc.6604950.
    1. Court Brown WM, Doll R. Leukaemia in childhood and young adult life. Br Med J. 1961;5231:981–988. doi: 10.1136/bmj.1.5231.981.
    1. Howard SC, Metzger ML, Willmas JA, Quintana Y, Pui CH, Robison LL, Ribeiro RC. Childhood cancer epidemiology in low-income countries. Cancer. 2008;112:461–472. doi: 10.1002/cncr.23205.
    1. Tomatis L. Poverty and cancer. IARC Sci Publ. 1997;138:25–39.
    1. Haupt R, Spinetta JJ, Ban I, Barr RD, Beck JD, Byrne J, Calaminui G, Coenen E, Chesler M,, D’Angio GJ, Eiser C, Feldges A, Gibson F, Lackner H, Masera G, Massimo L, Magyarosy E, Otten J, Reaman G, Valsecchi MG, Veerman AJP, Penn A, Thjorvildsen A, van den Bos C, Jankovic M. International Berlin-.Frankfurt-Muenster Study Group Early and Late Toxicity Educational Commnittee. Long term survivors of childhood cancer. Cure and care. The Erice statement. Eur J Cancer. 2007;43:1778–1780. doi: 10.1016/j.ejca.2007.04.015.

Source: PubMed

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