FIGO recommendations on the management of postpartum hemorrhage 2022

Maria Fernanda Escobar, Anwar H Nassar, Gerhard Theron, Eythan R Barnea, Wanda Nicholson, Diana Ramasauskaite, Isabel Lloyd, Edwin Chandraharan, Suellen Miller, Thomas Burke, Gabriel Ossanan, Javier Andres Carvajal, Isabella Ramos, Maria Antonia Hincapie, Sara Loaiza, Daniela Nasner, FIGO Safe Motherhood and Newborn Health Committee, Anwar H Nassar, Gerard H Visser, Eytan R Barnea, Maria Fernanda Escobar, Yoon Ha Kim, Wanda Kay Nicholson, Rodolfo Pacagnella, Diana Ramasauskaite, Gerhard Theron, Alison Wright, Maria Fernanda Escobar, Anwar H Nassar, Gerhard Theron, Eythan R Barnea, Wanda Nicholson, Diana Ramasauskaite, Isabel Lloyd, Edwin Chandraharan, Suellen Miller, Thomas Burke, Gabriel Ossanan, Javier Andres Carvajal, Isabella Ramos, Maria Antonia Hincapie, Sara Loaiza, Daniela Nasner, FIGO Safe Motherhood and Newborn Health Committee, Anwar H Nassar, Gerard H Visser, Eytan R Barnea, Maria Fernanda Escobar, Yoon Ha Kim, Wanda Kay Nicholson, Rodolfo Pacagnella, Diana Ramasauskaite, Gerhard Theron, Alison Wright

No abstract available

Keywords: FIGO recommendations; PPH; PPH prevention; PPH treatment; management; postpartum hemorrhage.

Conflict of interest statement

GT reports a research grant from the South African Medical Research Council to fund Sinapi Biomedical to develop the Ellavi UBT and conduct associated research. EB reports part ownership of BioIncept. EC was a member of the Guideline Development Group for the RCOG’s PPH Greentop Guideline (2016), and the FIGO Guideline on Placenta Acreta Spectrum (2018). SM reports that Regents, University of California receives a royalty fee from LifeWrap‐NASG for the use of the trademark name (“LifeWrap”) for a Non‐pneumatic Anti‐Shock Garment (NASG). TB reports PPH research funded by the Gates Foundation; PPH Implementation efforts funded by RzHC; PPH Implementation efforts funded by UK AID; PPH Implementation efforts funded by Grand Challenges Canada; PPH efforts and research funded by USAID; PPH efforts by Norway Government. Other authors report no conflicts of interest.

References

    1. World Health Organization . WHO Model List of Essential Medicines. Accessed December 16, 2021.
    1. Begley CM, Gyte GM, Devane D, McGuire W, Weeks A. Active versus expectant management for women in the third stage of labour. Cochrane Database Syst Rev. 2011(11):CD007412.
    1. Lalonde A; International Federation of Gynecology and Obstetrics . Prevention and treatment of postpartum hemorrhage in low‐resource settings. Int J Gynecol Obstet. 2012;117:108–118.
    1. World Health Organization . WHO recommendations for the prevention and treatment of postpartum haemorrhage. Accessed August 11, 2021.
    1. World Health Organization . WHO recommendations: Uterotonics for the prevention of postpartum haemorrhage. Accessed August 11, 2021.
    1. Oliver VL, Lambert PA, Than KK, et al Knowledge, perception and practice towards oxytocin stability and quality: a qualitative study of stakeholders in three resource limited countries. PLoS One. 2018;13:e0203810.
    1. Gallos I, Williams H, Price M, et al. Uterotonic drugs to prevent postpartum haemorrhage: a network meta‐analysis. Health Technol Assess. 2019;23:1–356.
    1. Hofmeyr GJ, Abdel‐Aleem H, Abdel‐Aleem MA. Uterine massage for preventing postpartum haemorrhage. Cochrane Database Syst Rev. 2013;(7):CD006431.
    1. International Federation of Gynecology and Obstetrics . Be an advocate for better PPH management. Accessed January 7, 2021.
    1. Morris JL, Winikoff B, Dabash R, et al FIGO's updated recommendations for misoprostol used alone in gynecology and obstetrics. Int J Gynecol Obstet. 2017;138:363–366.
    1. Perel P, Roberts I, Ker K. Colloids versus crystalloids for fluid resuscitation in critically ill patients. Cochrane Database Syst Rev. 2013;(2):CD000567.
    1. WOMAN Trial Collaborators . Effect of early tranexamic acid administration on mortality, hysterectomy, and other morbidities in women with post‐partum haemorrhage (WOMAN): an international, randomised, double‐blind, placebo‐controlled trial. Lancet. 2017;389:2105–2116.
    1. World Health Organization . WHO recommendation on tranexamic acid for the treatment of postpartum haemorrhage. Accessed August 11, 2021.
    1. Shakur H, Beaumont D, Pavord S, Gayet‐Ageron A, Ker K, Mousa H. Antifibrinolytic drugs for treating primary postpartum haemorrhage. Cochrane Database Syst Rev. 2018;(2):CD012964.
    1. World Health Organization . State of Inequality: Reproductive Maternal Newborn and Child Health: Interactive Visualization of Health Data. Accessed August 11, 2021.
    1. Tindell K, Garfinkel R, Abu‐Haydar E, et al Uterine balloon tamponade for the treatment of postpartum haemorrhage in resource‐poor settings: a systematic review. BJOG. 2013;120:5–14.
    1. Mahankali SS. Interventional radiology: a disruptive innovation which is transforming management of post‐partum haemorrhage. J Obstet Anaesth Crit Care. 2017;7:65–68.
    1. Mousa HA, Blum J, Abou El Senoun G, Shakur H, Alfirevic Z. Treatment for primary postpartum haemorrhage. Cochrane Database Syst Rev. 2014;(2):CD003249.
    1. Borovac‐Pinheiro A, Pacagnella RC, Cecatti JG, et al Postpartum hemorrhage: new insights for definition and diagnosis. Am J Obstet Gynecol. 2018;219:162–168.
    1. Calvert C, Thomas SL, Ronsmans C, Wagner KS, Adler AJ, Filippi V. Identifying regional variation in the prevalence of postpartum haemorrhage: a systematic review and meta‐analysis. PLoS One. 2012;7:e41114.
    1. Mehrabadi A, Liu S, Bartholomew S, et al Temporal trends in postpartum hemorrhage and severe postpartum hemorrhage in Canada from 2003 to 2010. J Obstet Gynaecol Can. 2014;36:21–33.
    1. Reale SC, Easter SR, Xu X, Bateman BT, Farber MK. Trends in Postpartum Hemorrhage in the United States From 2010 to 2014. Anesth Analg. 2020;130:e119–e122.
    1. Carroli G, Cuesta C, Abalos E, Gulmezoglu AM. Epidemiology of postpartum haemorrhage: a systematic review. Best Pract Res Clin Obstet Gynaecol. 2008;22:999–1012.
    1. Committee on Practice Bulletins‐Obstetrics . Practice bulletin no. 183: postpartum hemorrhage. Obstet Gynecol. 2017;130:e168–e186.
    1. Prevention and management of postpartum haemorrhage: green‐top guideline no. 52. BJOG. 2017;124:e106–e149.
    1. Dahlke JD, Mendez‐Figueroa H, Maggio L, et al Prevention and management of postpartum hemorrhage: a comparison of 4 national guidelines. Am J Obstet Gynecol. 2015;213:76.e1–76.e10.
    1. Pan American Health Organization . Guidelines for the prevention, diagnosis and treatment of obstetric hemorrhage [in Portuguese]. PAHO; 2018.
    1. Leduc D, Senikas V, Lalonde AB. No. 235‐active management of the third stage of labour: prevention and treatment of postpartum hemorrhage. J Obstet Gynaecol Can. 2018;40:e841–e855.
    1. Mavrides E, Allard S, Chandraharan E, et al.; on behalf of the Royal College of Obstetricians and Gynaecologists . Prevention and management of postpartum haemorrhage. BJOG. 2016;124:e106–e149.
    1. Sentilhes L, Vayssière C, Deneux‐Tharaux C, et al Postpartum hemorrhage: guidelines for clinical practice from the French College of Gynaecologists and Obstetricians (CNGOF): in collaboration with the French Society of Anesthesiology and Intensive Care (SFAR). Eur J Obstet Gynecol Reprod Biol. 2016;198:12–21.
    1. Royal Australian and New Zealand College of Obstetricians and Gynaecologists . RANZCOG statement. Management of postpartum hemorrhage. Accessed August 11, 2021.
    1. Sri Lanka College of Obstetrician and Gynecologists . SLCOG Guideline on Management of Primary PostPartum Haemorrhage. Accessed August 11, 2021.
    1. Shields LE, Goffman D, Caughey A; Committee on Practice Bulletins—Obstetrics . ACOG practice bulletin: Clinical management guidelines for obstetrician‐gynecologists. Obstet Gynecol. 2017;130(4):e168–e186.
    1. Schlembach D, Helmer H, Henrich W, et al. Peripartum haemorrhage, diagnosis and therapy. Guideline of the DGGG, OEGGG and SGGG (S2k Level, AWMF Registry No. 015/063, March 2016). Geburtshilfe Frauenheilkd. 2018;78:382–399.
    1. Fawcus S. Alerts for managing postpartum haemorrhage. S Afr Med J. 2018;108:1013–1017.
    1. Newsome J, Martin JG, Bercu Z, Shah J, Shekhani H, Peters G. Postpartum hemorrhage. Tech Vasc Interv Radiol. 2017;20:266–273.
    1. Anderson J, Etches D. Prevention and management of postpartum hemorrhage. Am Fam Physician. 2007;75:875–882.
    1. Oyelese Y, Anant CV. Postpartum hemorrhage: epidemiology, risk factors, and causes. Clin Obstet Gynecol. 2010;53:147–156.
    1. Sentilhes L, Merlot B, Madar H, Sztark F, Brun S, Deneux‐Tharaux C. Postpartum haemorrhage: prevention and treatment. Expert Rev Hematol. 2016;9:1043–1061.
    1. Sheiner E, Sarid L, Levy A, Seidman DS, Hallak M. Obstetric risk factors and outcome of pregnancies complicated with early postpartum hemorrhage: a population‐based study. J Matern Fetal Neonatal Med. 2005;18:149–154.
    1. Evensen A, Anderson JM, Fontaine P. Postpartum hemorrhage: prevention and treatment. Am Fam Physician. 2017;95:442–449.
    1. Einerson BD, Miller ES, Grobman WA. Does a postpartum hemorrhage patient safety program result in sustained changes in management and outcomes? Am J Obstet Gynecol. 2015;212:140–144.
    1. Shields LE, Wiesner S, Fulton J, Pelletreau B. Comprehensive maternal hemorrhage protocols reduce the use of blood products and improve patient safety. Am J Obstet Gynecol. 2015;212:272–280.
    1. Council on Patient Safety in Women's Health Care . Maternal safety. Accessed August 25, 2021.
    1. Institute for Healthcare Improvement . Evidence‐based care bundles. Accessed November 15, 2020.
    1. Main EK, Goffman D, Scavone BM, et al National partnership for maternal safety: consensus bundle on obstetric hemorrhage. Obstet Gynecol. 2015;126:155–162.
    1. California Maternal Quality Care Collaborative Improving Health Care Response to Obstetric Hemorrhage. Accessed November 8, 2021.
    1. Council on Patient Safety in Women's Health Care . Patient safety bundle: Obstetric hemorrhage. Accessed January 7, 2022.
    1. Althabe F, Therrien MNS, Pingray V, et al. Postpartum hemorrhage care bundles to improve adherence to guidelines: a WHO technical consultation. Int J Gynecol Obstet. 2020;148:290–299.
    1. Schorn MN. Measurement of blood loss: review of the literature. J Midwifery Womens Health. 2010;55:20–27.
    1. Borovac‐Pinheiro A, Pacagnella RC, Cecatti JG, et al Postpartum hemorrhage: new insights for definition and diagnosis. Am J Obstet Gynecol. 2018;219:162–168.
    1. Arulkumaran S, Karoshi M, Keith LG, Lalonde AB, B‐Lynch C. A comprehensive textbook of postpartum hemorrhage: an essential clinical reference for effective management. Sapiens Publishing; 2012.
    1. Rady MY, Nightingale P, Little RA, Edwards JD. Shock index: a re‐evaluation in acute circulatory failure. Resuscitation. 1992;23:227–234.
    1. Pacagnella RC, Souza JP, Durocher J, et al A systematic review of the relationship between blood loss and clinical signs. PLoS One. 2013;8:e57594.
    1. El Ayadi AM, Nathan HL, Seed PT, et al Vital sign prediction of adverse maternal outcomes in women with hypovolemic shock: the role of shock index. PLoS One. 2016;11:e0148729.
    1. Le Bas A, Chandraharan E, Addei A, Arulkumaran S. Use of the “obstetric shock index” as an adjunct in identifying significant blood loss in patients with massive postpartum hemorrhage. Int J Gynecol Obstet. 2014;124:253–255.
    1. Rady MY, Smithline HA, Blake H, Nowak R, Rivers E. A comparison of the shock index and conventional vital signs to identify acute, critical illness in the emergency department. Ann Emerg Med. 1994;24:685–690.
    1. Troiano NH, Witcher PM, Baird SM. High‐Risk & Critical Care Obstetrics. Lippincott Williams & Wilkins; 2018.
    1. Chandraharan E, Arulkumaran S. Obstetric and Intrapartum Emergencies: A Practical Guide to Management. Cambridge University Press; 2012.
    1. Vandromme MJ, Griffin RL, Kerby JD, McGwin G Jr, Rue LW 3rd, Weinberg JA. Identifying risk for massive transfusion in the relatively normotensive patient: utility of the prehospital shock index. J Trauma. 2011;70(2):384–390; discussion 388–90.
    1. Cannon CM, Braxton CC, Kling‐Smith M, Mahnken JD, Carlton E, Moncure M. Utility of the shock index in predicting mortality in traumatically injured patients. J Trauma. 2009;67:1426–1430.
    1. Nathan HL, El Ayadi A, Hezelgrave NL, et al Shock index: an effective predictor of outcome in postpartum haemorrhage? BJOG. 2015;122:268–275.
    1. Woolf SH, Grol R, Hutchinson A, Eccles M, Grimshaw J. Clinical guidelines: potential benefits, limitations, and harms of clinical guidelines. BMJ. 1999;318:527–530.
    1. Sentilhes L, Goffinet F, Vayssière C, Deneux‐Tharaux C. Comparison of postpartum haemorrhage guidelines: discrepancies underline our lack of knowledge. BJOG. 2017;124:718–722.
    1. Bohlmann MK, Rath W. Medical prevention and treatment of postpartum hemorrhage: a comparison of different guidelines. Arch Gynecol Obstet. 2014;289:555–567.
    1. Dahlke JD, Mendez‐Figueroa H, Maggio L, et al Prevention and management of postpartum hemorrhage: a comparison of 4 national guidelines. Am J Obstet Gynecol. 2015;213(1):76.e1–76.e10.
    1. Prevention and management of postpartum haemorrhage: green‐top guideline no. 52. BJOG. 2017;124:e106–e149.
    1. Sentilhes L, Vayssière C, Deneux‐Tharaux C, et al Postpartum hemorrhage: guidelines for clinical practice from the French College of Gynaecologists and Obstetricians (CNGOF): in collaboration with the French Society of Anesthesiology and Intensive Care (SFAR). Eur J Obstet Gynecol Reprod Biol. 2016;198:12–21.
    1. World Health Organization . WHO Recommendations for the Prevention and Treatment of Postpartum Haemorrhage. Accessed August 11, 2021.
    1. Committee on Practice Bulletins‐Obstetrics . Practice bulletin no. 183: postpartum hemorrhage. Obstet Gynecol. 2017;130:e168–e186.
    1. Schlembach D, Helmer H, Henrich W, et al. Peripartum haemorrhage, diagnosis and therapy. Guideline of the DGGG, OEGGG and SGGG (S2k Level, AWMF Registry No. 015/063, March 2016). Geburtshilfe Frauenheilkd. 2018;78:382–399.
    1. Leduc D, Senikas V, Lalonde AB. No 235‐active management of the third stage of labour: prevention and treatment of postpartum hemorrhage. J Obstet Gynaecol Can. 2018;40:e841–e855.
    1. Organization PAH. Guidelines for the prevention, diagnosis and treatment of obstetric hemorrhage [in Portuguese]. PAHO; 2018.
    1. Fawcus S. Alerts for managing postpartum haemorrhage. S Afr Med J. 2018;108:1013–1017.
    1. Sri Lanka College of Obstetrician and Gynecologists . SLCOG Guideline on Management of Primary PostPartum Haemorrhage. Accessed August 11, 2021.
    1. Fuchther C, Ortiz EI, Escobar MF, Lizaola H. Hemorragia Postparto: en donde estamos y hacia donde vamos. Federación Latinoamericna de Sociedades de Ginecologia y Obstetricia. Accessed August 11, 2021.
    1. Lalonde A; International Federation of Gynecology and Obstetrics . Prevention and treatment of postpartum hemorrhage in low‐resource settings. Int J Gynaecol Obstet. 2012;117(2):108–118.
    1. World Health Organization . WHO recommendations: Uterotonics for the prevention of postpartum haemorrhage. Accessed August 25, 2021.
    1. Althabe F, Therrien MNS, Pingray V, et al. Postpartum hemorrhage care bundles to improve adherence to guidelines: A WHO technical consultation. Int J Gynecol Obstet. 2020;148:290–299.
    1. Prevention and management of postpartum haemorrhage: green‐top guideline no. 52. BJOG. 2017;124:e106–e149.
    1. Sentilhes L, Vayssière C, Deneux‐Tharaux C, et al Postpartum hemorrhage: guidelines for clinical practice from the French College of Gynaecologists and Obstetricians (CNGOF): in collaboration with the French Society of Anesthesiology and Intensive Care (SFAR). Eur J Obstet Gynecol Reprod Biol. 2016;198:12–21.
    1. World Health Organization . WHO Recommendations for the Prevention and Treatment of Postpartum Haemorrhage. Accessed August 18, 2021.
    1. Schlembach D, Helmer H, Henrich W, et al. Peripartum haemorrhage, diagnosis and therapy. Guideline of the DGGG, OEGGG and SGGG (S2k Level, AWMF Registry No. 015/063, March 2016). Geburtshilfe Frauenheilkd. 2018;78:382–399.
    1. Leduc D, Senikas V, Lalonde AB. No. 235‐active management of the third stage of labour: prevention and treatment of postpartum hemorrhage. J Obstet Gynaecol Can. 2018;40:e841–e855.
    1. Committee on Practice Bulletins‐Obstetrics . Practice bulletin no. 183: postpartum hemorrhage. Obstet Gynecol. 2017;130:e168–e186.
    1. Organization PAH. Guidelines for the prevention, diagnosis and treatment of obstetric hemorrhage [in Portuguese]. PAHO; 2018.
    1. Fawcus S. Alerts for managing postpartum haemorrhage. S Afr Med J. 2018;108:1013–1017.
    1. Sri Lanka College of Obstetrician and Gynecologists . SLCOG Guideline on Management of Primary PostPartum Haemorrhage. Accessed August 25, 2021.
    1. Royal Australian and New Zealand College of Obstetricians and Gynaecologists . RANZCOG statement. Management of postpartum hemorrhage. Accessed August 25, 2021.
    1. WOMAN Trial Collaborators . Effect of early tranexamic acid administration on mortality, hysterectomy, and other morbidities in women with post‐partum haemorrhage (WOMAN): an international, randomised, double‐blind, placebo‐controlled trial. Lancet. 2017;389:2105–2116.
    1. World Health Organization . WHO Recommendation on Tranexamic Acid for the Treatment of Postpartum Haemorrhage. Accessed August 21: 2021.
    1. Vogel JP, Oladapo OT, Dowswell T, Gülmezoglu AM. Updated WHO recommendation on intravenous tranexamic acid for the treatment of post‐partum haemorrhage. Lancet Glob Health. 2018;6:e18–e19.
    1. Althabe F, Therrien MNS, Pingray V, et al. Postpartum hemorrhage care bundles to improve adherence to guidelines: a WHO technical consultation. Int J Gynecol Obstet. 2020;148:290–299.
    1. FIGO Safe Motherhood and Newborn Health Committee, International Federation of Gynecology and Obstetrics . Practice Guideline. Non‐pneumatic anti‐shock garment to stabilize women with hypovolemic shock secondary to obstetric hemorrhage. Int J Gynecol Obstet. 2015;128:194–195.
    1. Jauniaux E, Ayres‐de‐Campos D; FIGO Placenta Accreta Diagnosis and Management Expert Consensus Panel . FIGO consensus guidelines on placenta accreta spectrum disorders: Introduction. Int J Gynecol Obstet. 2018;140:261–264.
    1. Jauniaux E, Alfirevic Z, Bhide AG, et al. Placenta praevia and placenta accreta: diagnosis and management. BJOG. 2019;126(1):e1–e48.
    1. American College of Obstetricians and Gynecologists; Society for Maternal‐Fetal Medicine . Obstetric care consensus no. 7: placenta accreta spectrum. Obstet Gynecol. 2018;132:e259–e275.
    1. Fuchtner C, Ortiz EI, Escobar MF, Lizaola H. Hemorragia Postparto: en donde estamos y hacia donde vamos. Federación Latinoamericana de Sociedades de Ginecologia y Obstetricia. Accessed August 11, 2021.
    1. Hunter DJ, Schulz P, Wassenaar W. Effect of carbetocin, a long‐acting oxytocin analog on the postpartum uterus. Clin Pharmacol Ther. 1992;52:60–67.
    1. Arrowsmith S, Wray S. Oxytocin: its mechanism of action and receptor signalling in the myometrium. J Neuroendocrinol. 2014;26:356–369.
    1. Gallos ID, Coomarasamy A. Carbetocin: worth the extra expense? Best Pract Res Clin Obstet Gynaecol. 2019;61:55–65.
    1. Widmer M, Piaggio G, Nguyen TMH, et al Heat‐stable carbetocin versus oxytocin to prevent hemorrhage after vaginal birth. N Engl J Med. 2018;379:743–752.
    1. Gallos ID, Williams HM, Price MJ, et al. Uterotonic agents for preventing postpartum haemorrhage: a network meta‐analysis. Cochrane Database Syst Rev. 2018;(4):CD011689.
    1. Maged AM, Waly M, Fahmy RM, et al Carbetocin versus rectal misoprostol for management of third stage of labor among women with low risk of postpartum hemorrhage. Int J Gynecol Obstet. 2020;148:238–242.
    1. Reyes OA, Gonzalez GM. Carbetocin versus oxytocin for prevention of postpartum hemorrhage in patients with severe preeclampsia: a double‐blind randomized controlled trial. J Obstet Gynaecol Can. 2011;33:1099–1104.
    1. Su LL, Chong YS, Samuel M. Carbetocin for preventing postpartum haemorrhage. Cochrane Database Syst Rev. 2012;(2):CD005457.
    1. Voon HY, Suharjono HN, Shafie AA, Bujang MA. Carbetocin versus oxytocin for the prevention of postpartum hemorrhage: A meta‐analysis of randomized controlled trials in cesarean deliveries. Taiwan J Obstet Gynecol. 2018;57:332–339.
    1. Onwochei DN, Owolabi A, Singh PM, Monks DT. Carbetocin compared with oxytocin in non‐elective Cesarean delivery: a systematic review, meta‐analysis, and trial sequential analysis of randomized‐controlled trials. Can J Anaesth. 2020;67(11):1524–1534.
    1. Voon HY, Shafie AA, Bujang MA, Suharjono HN. Cost effectiveness analysis of carbetocin during cesarean section in a high volume maternity unit. J Obstet Gynaecol Res. 2018;44:109–116.
    1. Van der Nelson HA, Draycott T, Siassakos D, Yau CWH, Hatswell AJ. Carbetocin versus oxytocin for prevention of post‐partum haemorrhage at caesarean section in the United Kingdom: an economic impact analysis. Eur J Obstet Gynecol Reprod Biol. 2017;210:286–291.
    1. Luni Y, Borakati A, Matah A, Skeats K, Eedarapalli P. A prospective cohort study evaluating the cost‐effectiveness of carbetocin for prevention of postpartum haemorrhage in caesarean sections. J Obstet Gynaecol. 2017;37:601–604.
    1. Lawrie TA, Rogozińska E, Sobiesuo P, Vogel JP, Ternent L, Oladapo OT. A systematic review of the cost‐effectiveness of uterotonic agents for the prevention of postpartum hemorrhage. Int J Gynaecol Obstet. 2019;146(1):56–64.
    1. Mannaerts D, Van der Veeken L, Coppejans H, Jacquemyn Y. Adverse effects of carbetocin versus oxytocin in the prevention of postpartum haemorrhage after caesarean section: a randomized controlled trial. J Pregnancy. 2018;2018:1374150.
    1. Muggleton E. Oxytocin study raises concerns about carbetocin use. Anesth Analg. 2018;126:1423.
    1. Nguyen‐Lu N, Carvalho JC, Farine D, Seaward G, Ye XY, Balki M. Carbetocin at cesarean delivery for labour arrest: a sequential allocation trial to determine the effective dose. Can J Anaesth. 2015;62(8):866–874.
    1. Pérez‐Nieto OR, Castañón‐González JA, Lima‐Lucero IM, Delsol LAG. Near fatal bronchospasm and bradycardia after carbetocin administration. Med Intensiva. 2018;42:319–321.
    1. Ker K, Edwards P, Perel P, Shakur H, Roberts I. Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta‐analysis. BMJ. 2012;344:e3054.
    1. WOMAN Trial Collaborators . Effect of early tranexamic acid administration on mortality, hysterectomy, and other morbidities in women with post‐partum haemorrhage (WOMAN): an international, randomised, double‐blind, placebo‐controlled trial. Lancet. 2017;389:2105–2116.
    1. Gayet‐Ageron A, Prieto‐Merino D, Ker K, et al. Effect of treatment delay on the effectiveness and safety of antifibrinolytics in acute severe haemorrhage: a meta‐analysis of individual patient‐level data from 40 138 bleeding patients. Lancet. 2018;391:125–132.
    1. Shakur H, Beaumont D, Pavord S, Gayet‐Ageron A, Ker K, Mousa HA. Antifibrinolytic drugs for treating primary postpartum haemorrhage. Cochrane Database Syst Rev. 2018;(2):CD012964.
    1. Saccone G, Della Corte L, D’Alessandro P, et al Prophylactic use of tranexamic acid after vaginal delivery reduces the risk of primary postpartum hemorrhage. J Matern Fetal Neonatal Med. 2020;33:3368–3376.
    1. Ducloy‐Bouthors A‐S, Jude B, Duhamel A, et al High‐dose tranexamic acid reduces blood loss in postpartum haemorrhage. Crit Care. 2011;15:R117.
    1. Alam A, Choi S. Prophylactic use of tranexamic acid for postpartum bleeding outcomes: a systematic review and meta‐analysis of randomized controlled trials. Transfus Med Rev. 2015;29:231–241.
    1. Sentilhes L, Lasocki S, Ducloy‐Bouthors AS, et al Tranexamic acid for the prevention and treatment of postpartum haemorrhage. Br J Anaesth. 2015;114:576–587.
    1. Sentilhes L, Sénat MV, Le Lous M, et al Tranexamic acid for the prevention of blood loss after cesarean delivery. N Engl J Med. 2021;384:1623–1634.
    1. Mousa HA, Blum J, Abou El Senoun G, Shakur H, Alfirevic Z. Treatment for primary postpartum haemorrhage. Cochrane Database Syst Rev. 2014;(2):CD003249.
    1. Novikova N, Hofmeyr GJ, Cluver C. Tranexamic acid for preventing postpartum haemorrhage. Cochrane Database Syst Rev. 2015;(6):CD007872.
    1. Kramer MS, Berg C, Abenhaim H, et al Incidence, risk factors, and temporal trends in severe postpartum hemorrhage. Am J Obstet Gynecol. 2013;209(449):e1–7.
    1. Escobar MF, Füchtner CE, Carvajal JA, et al Experience in the use of non‐pneumatic anti‐ shock garment (NASG) in the management of postpartum haemorrhage with hypovolemic shock in the Fundación Valle Del Lili, Cali, Colombia. Reprod Health. 2017;14:58.
    1. Pileggi‐Castro C, Nogueira‐Pileggi V, Tunçalp Ö, Oladapo OT, Vogel JP, Souza JP. Non‐pneumatic anti‐shock garment for improving maternal survival following severe postpartum haemorrhage: a systematic review. Reprod Health. 2015;12:28.
    1. FIGO Safe Motherhood and Newborn Health Committee, International Federation of Gynecology and Obstetrics . Non‐pneumatic anti‐shock garment to stabilize women with hypovolemic shock secondary to obstetric hemorrhage. Int J Gynecol Obstet. 2015;128:194–195.
    1. Althabe F, Therrien MNS, Pingray V, et al. Postpartum hemorrhage care bundles to improve adherence to guidelines: a WHO technical consultation. Int J Gynecol Obstet. 2020;148:290–299.
    1. Miller S, Martin HB, Morris JL. Anti‐shock garment in postpartum haemorrhage. Best Pract Res Clin Obstet Gynaecol. 2008;22:1057–1074.
    1. Kerr NL, Hauswald M, Tamrakar SR, Wachter DA, Baty GM. An inexpensive device to treat postpartum hemorrhage: a preliminary proof of concept study of health provider opinion and training in Nepal. BMC Pregnancy Childbirth. 2014;14:81.
    1. Lester F, Stenson A, Meyer C, Morris J, Vargas J, Miller S. Impact of the Non‐pneumatic Antishock Garment on pelvic blood flow in healthy postpartum women. Am J Obstet Gynecol. 2011;204(409):e1–5.
    1. Hauswald M, Greene ER. Regional blood flow after pneumatic anti‐shock garment inflation. Prehosp Emerg Care. 2003;7:225–228.
    1. Mourad‐Youssif M, Ojengbede OA, Meyer CD, et al Can the Non‐pneumatic Anti‐Shock Garment (NASG) reduce adverse maternal outcomes from postpartum hemorrhage? Evidence from Egypt and Nigeria. Reprod Health. 2010;7:24.
    1. Miller S, Bergel EF, El Ayadi AM, et al Non‐pneumatic anti‐shock garment (NASG), a first‐ aid device to decrease maternal mortality from obstetric hemorrhage: a cluster randomized trial. PLoS One. 2013;8:e76477.
    1. Mbaruku G, Therrien MS, Tillya R, et al Implementation project of the non‐pneumatic anti‐ shock garment and m‐communication to enhance maternal health care in rural Tanzania. Reprod Health. 2018;15:177.
    1. World Health Organization . Managing complications in pregnancy and childbirth: a guide for midwives and doctors. Accessed August 11, 2021.
    1. Weeks A. The prevention and treatment of postpartum haemorrhage: what do we know, and where do we go to next? BJOG. 2015;122:202–210.
    1. Hofmeyr GJ, Qureshi Z. Preventing deaths due to haemorrhage. Best Pract Res Clin Obstet Gynaecol. 2016;36:68–82.
    1. Tunçalp O, Souza JP, Gülmezoglu M. World Health Organization. New WHO recommendations on prevention and treatment of postpartum hemorrhage. Int J Gynecol Obstet. 2013;123:254–256.
    1. Lalonde A; International Federation of Gynecology and Obstetrics . Prevention and treatment of postpartum hemorrhage in low‐resource settings. Int J Gynecol Obstet. 2012;117:108–118.
    1. Jordan K, Butrick E, Yamey G, Miller S. Barriers and facilitators to scaling up the non‐pneumatic anti‐shock garment for treating obstetric hemorrhage: a qualitative study. PLoS One. 2016;11:e0150739.
    1. Onyewuenyi A, Tilla R, Kinyonge I, et al. A qualitative approach to understanding the impact of misuse and misdiagnosis: Monitoring use of the non‐ pneumatic antishock garment in Tanzania. Annals of Global Health. 2016;82:489–490.
    1. Berdichevsky K, Tucker C, Martínez A, Miller S. Acceptance of a new technology for management of obstetric hemorrhage: a qualitative study from rural Mexico. Health Care Women Int. 2010;31:444–457.
    1. Begley CM, Gyte GM, Devane D, McGuire W, Weeks A. Active versus expectant management for women in the third stage of labour. Cochrane Database Syst Rev. 2011;(11):CD007412.
    1. Escobar MF, Füchtner CE, Carvajal JA, et al Experience in the use of non‐pneumatic anti‐ shock garment (NASG) in the management of postpartum haemorrhage with hypovolemic shock in the Fundación Valle Del Lili, Cali, Colombia. Reprod Health. 2017;14:58.
    1. Althabe F, Therrien MNS, Pingray V, et al. Postpartum hemorrhage care bundles to improve adherence to guidelines: a WHO technical consultation. Int J Gynecol Obstet. 2020;148:290–299.
    1. Laas E, Bui C, Popowski T, Mbaku OM, Rozenberg P. Trends in the rate of invasive procedures after the addition of the intrauterine tamponade test to a protocol for management of severe postpartum hemorrhage. Am J Obstet Gynecol. 2012;207(281):e1–7.
    1. Revert M, Cottenet J, Raynal P, Cibot E, Quantin C, Rozenberg P. Intrauterine balloon tamponade for management of severe postpartum haemorrhage in a perinatal network: a prospective cohort study. BJOG. 2017;124:1255–1262.
    1. Burke TF, Danso‐Bamfo S, Guha M, Oguttu M, Tarimo V, Nelson BD. Shock progression and survival after use of a condom uterine balloon tamponade package in women with uncontrolled postpartum hemorrhage. Int J Gynecol Obstet. 2017;139:34–38.
    1. Gauchotte E, De La Torre M, Perdriolle‐Galet E, Lamy C, Gauchotte G, Morel O. Impact of uterine balloon tamponade on the use of invasive procedures in severe postpartum hemorrhage. Acta Obstet Gynecol Scand. 2017;96(7):877–882.
    1. Revert M, Rozenberg P, Cottenet J, Quantin C. Intrauterine balloon tamponade for severe postpartum hemorrhage. Obstet Gynecol. 2018;131:143–149.
    1. Pendleton AA, Natarajan A, Ahn R, Nelson BD, Eckardt MJ, Burke TF. Emergency hysterectomy for uncontrolled postpartum hemorrhage may be averted through uterine balloon tamponade in Kenya and Senegal. Int J Gynecol Obstet. 2016;133:124.
    1. Pendleton AA, Natarajan A, Ahn R, Nelson BD, Eckardt MJ, Burke TF. A qualitative assessment of the impact of a uterine balloon tamponade package on decisions regarding the role of emergency hysterectomy in women with uncontrolled postpartum haemorrhage in Kenya and Senegal. BMJ Open. 2016;6:e010083.
    1. Suarez S, Conde‐Agudelo A, Borovac‐Pinheiro A, et al Uterine balloon tamponade for the treatment of postpartum hemorrhage: a systematic review and meta‐analysis. Am J Obstet Gynecol. 2020;222:293.e1–293.e52.
    1. Ramanathan A, Eckardt MJ, Nelson BD, et al Safety of a condom uterine balloon tamponade (ESM‐UBT) device for uncontrolled primary postpartum hemorrhage among facilities in Kenya and Sierra Leone. BMC Pregnancy Childbirth. 2018;18:168.
    1. Mishra N, Agrawal S, Gulabani K, Shrivastava C. Use of an innovative condom balloon tamponade in postpartum haemorrhage: a report. J Obstet Gynaecol India. 2016;66:63–67.
    1. Tolosa JE, Bakri YN, Arulkumaran S. Intrauterine balloon tamponade for control of postpartum hemorrhage. This topic last updated: March 12, 2018. Accessed August 25, 2021.
    1. Georgiou C. Balloon tamponade in the management of postpartum haemorrhage: a review. BJOG. 2009;116:748–757.
    1. Dildy GA, Belfort MA, Adair CD, et al Initial experience with a dual‐balloon catheter for the management of postpartum hemorrhage. Am J Obstet Gynecol. 2014;210(136):e1–6.
    1. Fawcus S, Moodley J. A Monograph of the Management of Postpartum Haemorrhage. National Committee for the Confidential Enquiries into Maternal Deaths in South Africa. National Department of Health South Africa. 2010.
    1. Theron GB. Management of postpartum hemorrhage with free‐flow pressure controlled uterine balloon. Int J Gynecol Obstet. 2018;142:371–373.
    1. Usage of the Zhukovsky Balloon Tamponade for PPH Free Flow balloon tamponade . 2014. Accessed August 25, 2021.
    1. Georgiou C. Intraluminal pressure readings during the establishment of a positive ‘tamponade test’ in the management of postpartum haemorrhage. BJOG. 2010;117:295–303.
    1. Cronjé HS, Cilliers JBF, du Toit MA. Clinical Obstetrics – a Southern African perspective, 4th edn. Van Schaik Publishers; 2016.
    1. Dumont A, Bodin C, Hounkpatin B, et al Uterine balloon tamponade as an adjunct to misoprostol for the treatment of uncontrolled postpartum haemorrhage: a randomised controlled trial in Benin and Mali. BMJ Open. 2017;7:e016590.
    1. Natarajan A, Alaska Pendleton A, Nelson BD, et al Provider experiences with improvised uterine balloon tamponade for the management of uncontrolled postpartum hemorrhage in Kenya. Int J Gynecol Obstet. 2016;135:210–213.
    1. Cho HY, Park YW, Kim YH, Jung I, Kwon JY. Efficacy of intrauterine Bakri balloon tamponade in cesarean section for placenta previa patients. PLoS One. 2015;10:e0134282.
    1. Soyama H, Miyamoto M, Sasa H, et al. Effect of routine rapid insertion of Bakri balloon tamponade on reducing hemorrhage from placenta previa during and after cesarean section. Arch Gynecol Obstet. 2017;296:469–474.
    1. Maher MA, Abdelaziz A. Comparison between two management protocols for postpartum hemorrhage during cesarean section in placenta previa: Balloon protocol versus non‐balloon protocol. J Obstet Gynaecol Res. 2017;43:447–455.
    1. Treloar EJ, Anderson RS, Andrews HS, Bailey JL. Uterine necrosis following B‐Lynch suture for primary postpartum haemorrhage. BJOG. 2006;113:486–488.
    1. Lodhi W, Golara M, Karangaokar V, Yoong W. Uterine necrosis following application of combined uterine compression suture with intrauterine balloon tamponade. J Obstet Gynaecol. 2012;32:30–31.
    1. Makin J, Suarez‐Rebling DI, Varma Shivkumar P, Tarimo V, Burke TF. Innovative uses of condom uterine balloon tamponade for postpartum hemorrhage in India and Tanzania. Case Rep Obstet Gynecol. 2018;2018:4952048.
    1. World Health Organization . WHO recommendation on uterine balloon tamponade for the treatment of postpartum haemorrhage. WHO; 2021. Accessed August 25, 2021.
    1. Kim TH, Lee HH, Kim JM, Ryu AL, Chung SH, Seok LW. Uterine artery embolization for primary postpartum hemorrhage. Iran J Reprod Med. 2013;11:511–518.
    1. Ganguli S, Stecker MS, Pyne D, Baum RA, Fan CM. Uterine artery embolization in the treatment of postpartum uterine hemorrhage. J Vasc Interv Radiol. 2011;22:169–176.
    1. Bros S, Chabrot P, Kastler A, et al Recurrent bleeding within 24 hours after uterine artery embolization for severe postpartum hemorrhage: are there predictive factors? Cardiovasc Intervent Radiol. 2012;35:508–514.
    1. Hong TM, Tseng HS, Lee RC, Wang JH, Chang CY. Uterine artery embolization: an effective treatment for intractable obstetric haemorrhage. Clin Radiol. 2004;59:96–101.
    1. Jung HN, Shin SW, Choi S‐J, et al Uterine artery embolization for emergent management of postpartum hemorrhage associated with placenta accreta. Acta Radiol. 2011;52:638–642.
    1. Soyer P, Morel O, Fargeaudou Y, et al Value of pelvic embolization in the management of severe postpartum hemorrhage due to placenta accreta, increta or percreta. Eur J Radiol. 2011;80:729–735.
    1. Diop AN, Chabrot P, Bertrand A, et al Placenta accreta: management with uterine artery embolization in 17 cases. J Vasc Interv Radiol. 2010;21:644–648.
    1. Wee L, Barron J, Toye R. Management of severe postpartum haemorrhage by uterine artery embolization. Br J Anaesth. 2004;93:591–594.
    1. Mahankali SS. Interventional radiology: a disruptive innovation which is transforming management of post‐partum haemorrhage. Journal of Obstetric Anaesthesia and Critical Care. 2017;7:65–68.
    1. Angstmann T, Gard G, Harrington T, Ward E, Thomson A, Giles W. Surgical management of placenta accreta: a cohort series and suggested approach. Am J Obstet Gynecol. 2010;202(38):e1–9.
    1. Mushtaq S, Kurdi W, Al‐Shammari M. Prophylactic catheters placement and intraoperative internal iliac artery embolisation in a patient with placenta accreta. J Obstet Gynaecol. 2007;27:853–855.
    1. Thon S, McLintic A, Wagner Y. Prophylactic endovascular placement of internal iliac occlusion balloon catheters in parturients with placenta accreta: a retrospective case series. Int J Obstet Anesth. 2011;20:64–70.
    1. Ojala K, Perälä J, Kariniemi J, Ranta P, Raudaskoski T, Tekay A. Arterial embolization and prophylactic catheterization for the treatment for severe obstetric hemorrhage. Acta Obstet Gynecol Scand. 2005;84:1075–1080.
    1. Badawy SZ, Etman A, Singh M, Murphy K, Mayelli T, Philadelphia M. Uterine artery embolization: the role in obstetrics and gynecology. Clin Imaging. 2001;25:288–295.
    1. Gizzo S, Saccardi C, Patrelli TS, et al. Fertility rate and subsequent pregnancy outcomes after conservative surgical techniques in postpartum hemorrhage: 15 years of literature. Fertil Steril. 2013;99(7):2097–2107.
    1. Lee HY, Shin JH, Kim J, et al Primary postpartum hemorrhage: outcome of pelvic arterial embolization in 251 patients at a single institution. Radiology. 2012;264:903–909.
    1. Gibbins KJ, Einerson BD, Varner MW, Silver RM. Placenta previa and maternal hemorrhagic morbidity. J Matern Fetal Neonatal Med. 2018;31(4):494–499.
    1. Huijgen QCA, Gijsen AF, Hink E, Van Kesteren PJM. Cervical tourniquet in case of uncontrollable haemorrhage during caesarean section owing to a placenta accreta. Case Reports. 2013;2013(apr22 1):bcr2013009237.
    1. Kato S, Tanabe A, Kanki K, et al Local injection of vasopressin reduces the blood loss during cesarean section in placenta previa. J Obstet Gynaecol Res. 2014;40:1249–1256.
    1. Arduini M, Epicoco G, Clerici G, Bottaccioli E, Arena S, Affronti G. B‐Lynch suture, intrauterine balloon, and endouterine hemostatic suture for the management of postpartum hemorrhage due to placenta previa accreta. Int J Gynecol Obstet. 2010;108(3):191–193.
    1. Kayem G, Kurinczuk JJ, Alfirevic Z, Spark P, Brocklehurst P, Knight M. Specific second‐line therapies for postpartum haemorrhage: a national cohort study. BJOG. 2011;118:856–864.
    1. Joshi VM, Shrivastava M. Partial ischemic necrosis of the uterus following a uterine brace compression suture. BJOG. 2004;111:279–280.
    1. Ochoa M, Allaire AD, Stitely ML. Pyometria after hemostatic square suture technique. Obstet Gynecol. 2002;99:506–509.
    1. Wu HH, Yeh GP. Uterine cavity synechiae after hemostatic square suturing technique. Obstet Gynecol. 2005;105(5 Pt 2):1176–1178.
    1. Mousa HA, Blum J, Abou El Senoun G, Shakur H, Alfirevic Z. Treatment for primary postpartum haemorrhage. Cochrane Database Syst Rev. 2014;(2):CD003249.
    1. Cunningham FG, Leveno KJ, Bloom SL, et al. Williams Obstetrics, 23rd edn. McGrawHill; 2010.
    1. B‐Lynch C, Coker A, Lawal AH, Abu J, Cowen MJ. The B‐Lynch surgical technique for the control of massive postpartum haemorrhage: an alternative to hysterectomy? Five cases reported. Br J Obstet Gynaecol. 1997;104:372–375.
    1. Hayman RG, Arulkumaran S, Steer PJ. Uterine compression sutures: surgical management of postpartum hemorrhage. Obstet Gynecol. 2002;99:502–506.
    1. Pereira A, Nunes F, Pedroso S, Saraiva J, Retto H, Meirinho M. Compressive uterine sutures to treat postpartum bleeding secondary to uterine atony. Obstet Gynecol. 2005;106:569–572.
    1. Price N, B‐Lynch C. Technical description of the B‐Lynch brace suture for treatment of massive postpartum hemorrhage and review of published cases. Int J Fertil Womens Med. 2005;50:148–163.
    1. Doumouchtsis SK, Papageorghiou AT, Arulkumaran S. Systematic review of conservative management of postpartum hemorrhage: what to do when medical treatment fails. Obstet Gynecol Surv. 2007;62:540–547.
    1. O'Leary JL, O'Leary JA. Uterine artery ligation in the control of intractable postpartum hemorrhage. Am J Obstet Gynecol. 1966;94(7):920–924.
    1. Verit FF, Çetin O, Keskin S, Akyol H, Zebitay AG. Does bilateral uterine artery ligation have negative effects on ovarian reserve markers and ovarian artery blood flow in women with postpartum hemorrhage? Clin Exp Reprod Med. 2019;46(1):30–35.
    1. Joshi VM, Otiv SR, Majumder R, Nikam YA, Shrivastava M. Internal iliac artery ligation for arresting postpartum haemorrhage. BJOG. 2007;114:356–361.
    1. Papp Z, Tóth‐Pál E, Papp C, et al. Hypogastric artery ligation for intractable pelvic hemorrhage. Int J Gynecol Obstet. 2006;92(1):27–31.
    1. Ledee N, Ville Y, Musset D, Mercier F, Frydman R, Fernandez H. Management in intractable obstetric haemorrhage: an audit study on 61 cases. Eur J Obstet Gynecol Reprod Biol. 2001;94:189–196.
    1. Unal O, Kars B, Buyukbayrak EE, Karsidag AY, Turan C. The effectiveness of bilateral hypogastric artery ligation for obstetric hemorrhage in three different underlying conditions and its impact on future fertility. J Matern Fetal Neonatal Med. 2011;24:1273–1276.
    1. Abbas AM, Shady NW, Sallam HF. Bilateral uterine artery ligation plus intravenous tranexamic acid during cesarean delivery for placenta previa: a randomized double‐blind controlled trial. J Gynecol Obstet Hum Reprod. 2019;48(2):115–119.
    1. Kaya B, Tuten A, Daglar K, et al B‐Lynch uterine compression sutures in the conservative surgical management of uterine atony. Arch Gynecol Obstet. 2015;291(5):1005–1014.
    1. Kaya B, Tuten A, Daglar K, et al Balloon tamponade for the management of postpartum uterine hemorrhage. J Perinat Med. 2014;42(6):745–753.
    1. Danisman N, Kahyaoglu S, Celen S, et al. The outcomes of surgical treatment modalities to decrease "near miss" maternal morbidity caused by peripartum hemorrhage. Eur Rev Med Pharmacol Sci. 2014;18(7):1092–1097.
    1. Kaya B, Damarer Z, Daglar K, Unal O, Soliman A, Guralp O. Is there yet a role for internal iliac artery ligation in obstetric hemorrhage with the current gain in popularity of other uterus sparing techniques? J Matern Fetal Neonatal Med. 2017;30(11):1325–1332.
    1. American College of Obstetricians and Gynecologists . ACOG Practice Bulletin: Clinical Management Guidelines for Obstetrician‐Gynecologists Number 76, October 2006: postpartum hemorrhage. Obstet Gynecol. 2006;108(4):1039–1047.
    1. Vanwinkel S, Claes L, Van den Bosch T. Obstetrical outcome after B‐Lynch sutures and ligation of uterine arteries: a case report. Case Rep Womens Health. 2021;30:e00303.
    1. Kellie FJ, Wandabwa JN, Mousa HA, Weeks AD. Mechanical and surgical interventions for treating primary postpartum haemorrhage. Cochrane Database Syst Rev. 2020;(7):CD013663.
    1. Burchell RC. Physiology of internal iliac artery ligation. J Obstet Gynaecol Br Commonw. 1968;75:642–651.
    1. Joshi VM, Otiv SR, Majumder R, Nikam YA, Shrivastava M. Internal iliac artery ligation for arresting postpartum haemorrhage. BJOG. 2007;114:356–361.
    1. Wang CY, Pan HH, Chang CC, Lin CK. Outcomes of hypogastric artery ligation and transcatheter uterine artery embolization in women with postpartum hemorrhage. Taiwan J Obstet Gynecol. 2019;58:72–76.
    1. Selçuk İ, Uzuner B, Boduç E, Baykuş Y, Akar B, Güngör T. Step‐by‐step ligation of the internal iliac artery. J Turk Ger Gynecol Assoc. 2019;20:123–128.
    1. B‐Lynch C, Keith LG, Campbell WB. Internal iliac (hypogastric) artery ligation. In: Arulkumaran S, Karoshi M, Keith LG, Lalonde AB, B‐Lynch C. eds. A Comprehensive Textbook of Postpartum Hemorrhage, 2nd edn. Sapiens Publishing; 2012:441–447.
    1. Demirci O, Tuğrul AS, Yilmaz E, Tosun Ö, Demirci E, Eren YS. Emergency peripartum hysterectomy in a tertiary obstetric center: nine years evaluation. J Obstet Gynaecol Res. 2011;37:1054–1060.
    1. Van den Akker T, Brobbel C, Dekkers OM, Bloemenkamp KW. Prevalence, indications, risk indicators, and outcomes of emergency peripartum hysterectomy worldwide: a systematic review and meta‐analysis. Obstet Gynecol. 2016;128:1281–1294.
    1. Bateman BT, Mhyre JM, Callaghan WM, Kuklina EV. Peripartum hysterectomy in the United States: nationwide 14 year experience. Am J Obstet Gynecol. 2012;206(63):e1–8.
    1. Temizkan O, Angın D, Karakuş R, Şanverdi İ, Polat M, Karateke A. Changing trends in emergency peripartum hysterectomy in a tertiary obstetric center in Turkey during 2000–2013. J Turk Ger Gynecol Assoc. 2016;17:26–34.
    1. Chawla J, Arora D, Paul M, Ajmani SN. Emergency obstetric hysterectomy: a retrospective study from a Teaching Hospital in North India over eight years. Oman Med J. 2015;30:181–186.
    1. Danisman N, Baser E, Togrul C, Kaymak O, Tandogan M, Gungor T. Emergency peripartum hysterectomy: experience of a major referral hospital in Ankara. Turkey. J Obstet Gynaecol. 2015;35:19–21.
    1. Jones B, Zhang E, Alzouebi A, et al Maternal and perinatal outcomes following peripartum hysterectomy from a single tertiary centre. Aust N Z J Obstet Gynaecol. 2013;53:561–565.
    1. Wong TY. Emergency peripartum hysterectomy: a 10‐year review in a tertiary obstetric hospital. N Z Med J. 2011;124:34–39.
    1. Awan N, Bennett MJ, Walters WA. Emergency peripartum hysterectomy: a 10‐year review at the Royal Hospital for Women, Sydney. Aust N Z J Obstet Gynaecol. 2011;51:210–215.
    1. Akintayo AA, Olagbuji BN, Aderoba AK, Akadiri O, Olofinbiyi BA, Bakare B. Emergency peripartum hysterectomy: a multicenter study of incidence, indications and outcomes in Southwestern Nigeria. Matern Child Health J. 2016;20:1230–1236.
    1. Pacheco LD, Saade GR, Gei AF, Hankins GD. Cutting‐edge advances in the medical management of obstetrical hemorrhage. Am J Obstet Gynecol. 2011;205:526–532.
    1. Ordóñez CA, Nieto AJ, Carvajal JA, et al Damage control surgery for the management of major obstetric hemorrhage: experience from the Fundación Valle del Lili, Cali, Colombia. Panamerican Journal of Trauma, Critical Care and Emergency Surgery. 2017;6:1–7.
    1. Clark SL, Hankins GD. Preventing maternal death: 10 clinical diamonds. Obstet Gynecol. 2012;119(2 Pt 1):360–364.
    1. Carvajal JA, Ramos I, Kusanovic JP, Escobar MF. Damage‐control resuscitation in obstetrics. J Matern Fetal Neonatal Med. 2022;35:785–798.
    1. Bogert JN, Harvin JA, Cotton BA. Damage control resuscitation. J Intensive Care Med. 2016;31:177–186.
    1. West N, Dawes R. Trauma resuscitation and the damage control approach. Surgery. 2018;36:409–416.
    1. Pacheco LD, Lozada MJ, Saade GR, Hankins GDV. Damage‐control surgery for obstetric hemorrhage. Obstet Gynecol. 2018;132:423–427.
    1. Ordoñez CA, Badiel M, Pino LF, et al Damage control resuscitation: Early decision strategies in abdominal gunshot wounds using an easy “ABCD” mnemonic. J Trauma Acute Care Surg. 2012;73:1074–1078.
    1. Gungor T, Simsek A, Ozdemir AO, Pektas M, Danisman N, Mollamahmutoglu L. Surgical treatment of intractable postpartum hemorrhage and changing trends in modern obstetric perspective. Arch Gynecol Obstet. 2009;280:351–355.
    1. Mukherjee S, Arulkumaran S. Post‐partum haemorrhage. Obstet Gynaecol Reprod Med. 2009;19:121–126.
    1. Zhang Y, Yan J, Han Q, et al Emergency obstetric hysterectomy for life‐threatening postpartum hemorrhage: a 12‐year review. Medicine. 2017;96:e8443.
    1. Escobar MF, García A, Fonseca J, Herrera E, Guerrero JE. Cirugía de control de daños: un concepto aplicable en ginecología y obstetricia. Colombia Médica. 2005;36:110–114.
    1. Goldberg SR, Anand RJ, Como JJ, et al Prophylactic antibiotic use in penetrating abdominal trauma: an Eastern Association for the Surgery of Trauma practice management guideline. J Trauma Acute Care Surg. 2012;73(5 Suppl 4):S321–S325.
    1. Godat L, Kobayashi L, Costantini T, Coimbra R. Abdominal damage control surgery and reconstruction: world society of emergency surgery position paper. World J Emerg Surg. 2013;8:53.
    1. Griggs C, Butler K. Damage control and the open abdomen: challenges for the nonsurgical intensivist. J Intensive Care Med. 2016;31:567–576.
    1. Kirkpatrick AW, Roberts DJ, De Waele J, et al Intra‐abdominal hypertension and the abdominal compartment syndrome: updated consensus definitions and clinical practice guidelines from the World Society of the Abdominal Compartment Syndrome. Intensive Care Med. 2013;39:1190–1206.
    1. Burlew CC. The open abdomen: practical implications for the practicing surgeon. Am J Surg. 2012;204:826–835.
    1. American College of Obstetricians and Gynecologists . ACOG Practice Bulletin: Clinical Management Guidelines for Obstetrician‐Gynecologists Number 76, October 2006: postpartum hemorrhage. Obstet Gynecol. 2006;108:1039–1047.
    1. Owattanapanich N, Chittawatanarat K, Benyakorn T, Sirikun J. Risks and benefits of hypotensive resuscitation in patients with traumatic hemorrhagic shock: a meta‐analysis. Scand J Trauma Resusc Emerg Med. 2018;26:107.
    1. Cannon JW. Hemorrhagic shock. N Engl J Med. 2018;378:370–379.
    1. Wang H, Chen MB, Zheng XW, Zheng QH. Effectiveness and safety of hypotensive resuscitation in traumatic hemorrhagic shock: a protocol for meta‐analysis. Medicine. 2019;98:e18145.
    1. Carrick MM, Leonard J, Slone DS, Mains CW, Bar‐Or D. Hypotensive resuscitation among trauma patients. Biomed Res Int. 2016;2016:8901938.
    1. Johansson PI, Oliveri RS, Ostrowski SR. Hemostatic resuscitation with plasma and platelets in trauma. J Emerg Trauma Shock. 2012;5:120–125.
    1. Pacheco LD, Saade GR, Costantine MM, Clark SL, Hankins GD. An update on the use of massive transfusion protocols in obstetrics. Am J Obstet Gynecol. 2016;214:340–344.
    1. Zwinkels RLJ, Endeman H, Hoeks SE, de Maat MPM, den Hartog D, Stolker RJ. The clinical effect of hemostatic resuscitation in traumatic hemorrhage; a before‐after study. J Crit Care. 2020;56:288–293.
    1. Spinella PC, Pidcoke HF, Strandenes G, et al. Whole blood for hemostatic resuscitation of major bleeding. Transfusion. 2016;56(Suppl 2):S190–202.
    1. Carvajal JA, Ramos I, Kusanovic JP, Escobar MF. Damage‐control resuscitation in obstetrics. J Matern Fetal Neonatal Med. 2022;35:785–798.
    1. Bouglé A, Harrois A, Duranteau J. Resuscitative strategies in traumatic hemorrhagic shock. Ann Intensive Care. 2013;3:1.
    1. Spahn DR, Bouillon B, Cerny V, et al. The European guideline on management of major bleeding and coagulopathy following trauma. Crit Care. 2019;23:98.
    1. Gillissen A, van den Akker T, Caram‐Deelder C, et al. Association between fluid management and dilutional coagulopathy in severe postpartum haemorrhage: a nationwide retrospective cohort study. BMC Pregnancy Childbirth. 2018;18:398.
    1. Henriquez DDCA, Bloemenkamp KWM, Loeff RM, et al. Fluid resuscitation during persistent postpartum haemorrhage and maternal outcome: a nationwide cohort study. Eur J Obstet Gynecol Reprod Biol. 2019;235:49–56.
    1. Pham HP, Shaz BH. Update on massive transfusion. Br J Anaesth. 2013;111(Suppl 1):i71–82.
    1. Holcomb JB, del Junco DJ, Fox EE, et al. The prospective, observational, multicenter, major trauma transfusion (PROMMTT) study: comparative effectiveness of a time‐varying treatment with competing risks. JAMA Surg. 2013;148:127–136.
    1. del Junco DJ, Holcomb JB, Fox EE, et al. Resuscitate early with plasma and platelets or balance blood products gradually: findings from the PROMMTT study. J Trauma Acute Care Surg. 2013;75(1 Suppl 1):S24–30.
    1. Holcomb JB, Tilley BC, Baraniuk S, et al. Transfusion of plasma, platelets, and red blood cells in a 1:1:1 vs a 1:1:2 ratio and mortality in patients with severe trauma: the PROPPR randomized clinical trial. JAMA. 2015;313:471–482.
    1. Tanaka H, Matsunaga S, Yamashita T, et al. A systematic review of massive transfusion protocol in obstetrics. Taiwan J Obstet Gynecol. 2017;56:715–718.
    1. Clark SL, Hankins GD. Preventing maternal death: 10 clinical diamonds. Obstet Gynecol. 2012;119(2 Pt 1):360–364.
    1. Bingham D, Melsop K, Main E. CMQCC Obstetric Hemorrhage Toolkit Hospital Level Implementation Guide. The California Maternal Quality Care Collaborative (CMQCC). Stanford University School of Medicine; 2010.
    1. Committee on Practice Bulletins‐Obstetrics . Practice bulletin no. 183: postpartum hemorrhage. Obstet Gynecol. 2017;130:e168–e186.
    1. Pacheco LD, Saade GR, Costantine MM, Clark SL, Hankins GD. The role of massive transfusion protocols in obstetrics. Am J Perinatol. 2013;30:1–4.
    1. Kogutt BK, Vaught AJ. Postpartum hemorrhage: Blood product management and massive transfusion. Semin Perinatol. 2019;43:44–50.
    1. Vasudev R, Sawhney V, Dogra M, Raina TR. Transfusion‐related adverse reactions: from institutional hemovigilance effort to National Hemovigilance program. Asian J Transfus Sci. 2016;10:31–36.
    1. Lalonde A. International Federation of Gynecology and Obstetrics . Prevention and treatment of postpartum hemorrhage in low‐resource settings. Int J Gynecol Obstet. 2012;117:108‐118.

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